isoimmunization

简明释义

英[ˌaɪsəʊˌɪmjunaɪˈzeɪʃən]美[aɪsoʊɪmjʊnaɪˈzeɪʃn]

n. 同种免疫接种；[免疫] 同族免疫作用

英英释义

单词用法

同义词

反义词

例句

1.D immunoglobulin (RhoGAM) is administered to Rh-negative, unsensitized patients to prevent isoimmunization.

为避免同种免疫，给未致敏的Rh血型阴性患者注射D免疫球蛋白（RhoGAM）。

2.D immunoglobulin (RhoGAM) is administered to Rh-negative, unsensitized patients to prevent isoimmunization.

为避免同种免疫，给未致敏的Rh血型阴性患者注射D免疫球蛋白（RhoGAM）。

3.The doctor explained that isoimmunization could lead to complications during pregnancy.

医生解释说，免疫不相容可能会导致怀孕期间的并发症。

4.In cases of Rh incompatibility, isoimmunization is a significant concern for expectant mothers.

在Rh不相容的情况下，免疫不相容是准妈妈们一个重要的关注点。

5.Routine blood tests can help detect isoimmunization early in pregnancy.

常规血液检测可以帮助在怀孕早期发现免疫不相容。

6.Healthcare providers often monitor for signs of isoimmunization after birth.

医疗服务提供者通常在出生后监测免疫不相容的迹象。

7.A history of isoimmunization in previous pregnancies can affect future pregnancies.

之前怀孕有过免疫不相容的历史可能会影响未来的怀孕。

作文

Isoimmunization is a medical term that refers to the immune response of an individual to foreign antigens that are present on the red blood cells of another individual of the same species. This phenomenon is particularly significant in the context of pregnancy, where it can lead to serious complications for the fetus. In this essay, we will explore the concept of isoimmunization and its implications in maternal-fetal medicine, as well as its prevention and management strategies. During pregnancy, a mother’s body may be exposed to the blood type of her fetus, especially if the fetus has a different Rh factor than the mother. If the mother is Rh-negative and the fetus is Rh-positive, the mother’s immune system may recognize the Rh-positive blood cells as foreign and produce antibodies against them. This process is known as isoimmunization or Rh alloimmunization. The antibodies can cross the placenta and attack the fetal red blood cells, leading to hemolytic disease of the newborn (HDN). The consequences of isoimmunization can be severe. HDN can result in anemia, jaundice, and in severe cases, heart failure or even stillbirth. Therefore, understanding isoimmunization is crucial for healthcare providers in order to monitor and manage pregnancies at risk. Routine screening for blood types and Rh factor is performed early in pregnancy to identify mothers who may be at risk for isoimmunization. If a mother is found to be Rh-negative, she is typically given an injection of Rh immunoglobulin (RhIg) during pregnancy and after delivery to prevent the development of antibodies against Rh-positive blood cells. In addition to Rh factor incompatibility, isoimmunization can also occur due to other blood group antigens, such as the ABO blood group system. Although ABO incompatibility is generally less severe than Rh incompatibility, it can still lead to jaundice and other complications in the newborn. Understanding the various factors that contribute to isoimmunization allows healthcare professionals to take proactive measures to protect both the mother and the child. Moreover, education plays a vital role in preventing isoimmunization. Expectant mothers should be informed about the importance of prenatal care, blood typing, and the potential risks associated with isoimmunization. By fostering awareness, healthcare providers can empower women to seek timely medical intervention and adhere to recommended guidelines. This proactive approach not only enhances maternal health but also improves outcomes for newborns. In conclusion, isoimmunization is a critical concept in obstetrics that highlights the complex interactions between a mother’s immune system and her fetus. With proper screening, preventive measures, and education, the risks associated with isoimmunization can be significantly reduced. As we continue to advance our understanding of immunology and maternal-fetal medicine, it is essential to prioritize research and clinical practices that enhance the health and well-being of both mothers and their children. The implications of isoimmunization extend beyond individual cases, influencing public health policies and practices aimed at improving maternal and neonatal outcomes across populations.

“Isoimmunization”是一个医学术语，指的是个体对另一同种生物的红细胞上存在的外来抗原的免疫反应。这一现象在妊娠过程中尤为重要，因为它可能导致胎儿严重并发症。在本文中，我们将探讨isoimmunization的概念及其在母胎医学中的影响，以及预防和管理策略。 在妊娠期间，母体可能会接触到胎儿的血型，尤其是在胎儿与母亲的Rh因子不同的情况下。如果母亲是Rh阴性而胎儿是Rh阳性，母亲的免疫系统可能会将Rh阳性红细胞视为外来物质，从而产生抗体。这个过程被称为isoimmunization或Rh免疫。这些抗体可以穿过胎盘，攻击胎儿的红细胞，导致新生儿溶血病（HDN）。 isoimmunization的后果可能是严重的。HDN可能导致贫血、黄疸，在严重的情况下甚至心力衰竭或死胎。因此，理解isoimmunization对于医疗提供者监测和管理高风险妊娠至关重要。常规筛查血型和Rh因子是在妊娠早期进行，以识别可能面临isoimmunization风险的母亲。如果发现母亲是Rh阴性，通常会在妊娠期间和分娩后给予Rh免疫球蛋白（RhIg）注射，以防止产生针对Rh阳性红细胞的抗体。 除了Rh因子不兼容外，isoimmunization还可能由于其他血型抗原（如ABO血型系统）而发生。尽管ABO不兼容通常比Rh不兼容轻微，但仍然可能导致黄疸和新生儿其他并发症。了解导致isoimmunization的各种因素使医疗专业人员能够采取积极措施，以保护母亲和孩子。 此外，教育在预防isoimmunization中发挥着重要作用。期望母亲应了解产前护理、血型检测和与isoimmunization相关的潜在风险的重要性。通过增强意识，医疗提供者可以赋予女性寻求及时医疗干预和遵循推荐指南的能力。这种积极主动的方法不仅提高了母亲的健康状况，还改善了新生儿的结果。 总之，isoimmunization是产科中的一个关键概念，突显了母亲免疫系统与胎儿之间复杂的相互作用。通过适当的筛查、预防措施和教育，可以显著降低与isoimmunization相关的风险。随着我们继续深化对免疫学和母胎医学的理解，优先研究和临床实践以促进母亲和儿童的健康与福祉至关重要。isoimmunization的影响超越个案，影响公共卫生政策和旨在改善各人群母婴结果的实践。