thromboxane

简明释义

英[θrɒmˈbɒkseɪn]美[θrɑːmˈbɑːkseɪn]

n. 血栓素，凝血噁烷

英英释义

单词用法

同义词

反义词

例句

1.AIM: To observe the effect of extract of Ginkgo biloba leaves on plasminogen activator inhibitor 1(PAI-1)and thromboxane B2(TXB-2)in type 2 diabetes mellitus(DM).

目的：观察银杏叶提取物对2型糖尿病病人纤溶酶原激活物抑制物1（PAI 1）及凝血烷B2（TXB 2 ）的影响。

2.Objective: To investigate Tangshenbao Decoction's influence on the oxidation irritable reaction and plasma thromboxane level in kidneys of diabetic rats.

目的：研究糖肾保煎剂对糖尿病大鼠肾脏氧化应激反应和血浆血栓素水平的影响。

3.Objective: To study the change in plasma levels of thromboxane (TXA2) prostacycline (PGI2) and endothelin (ET) in patients of diabetes mellitus complicated with angiopathy.

目的：探讨糖尿病合并血管并发症患者血浆血栓素A2（TXA2）、前列环素（PGI2）和内皮素（ET）水平的变化。

4.Objective To study the metabolizational status of plasma thromboxane A2 and PGI2 in patients of deficiency of pulmonary Qi.

目的探讨中医肺气虚证患者血浆血栓素、前列环素代谢状况。

5.Objective To investigate the relationship between serum thromboxane A2 (TXA2) and cerebral infarction.

目的探讨血清中血栓素a2 (TXA2)含量与脑梗死的关系。

6.The TMV also induced the formation of Thromboxane A2 (TXA2) of platelets.

TMV还可以诱导血小板血栓恶烷A_2的形成。

7.Method Plasma 11-dehydrothromboxane B2(DH-TXB2) and thromboxane B2(TXB2) were detected using ELISA in 38 PIH patients and 20 normal non-pregnant women.

方法采用酶联免疫吸附法（ELISA）检测38例PIH患者血浆11-去氢-血栓烷B2（DH-TXB2），同时测定TXB2，并与正常未孕组比较。

8."Aspirin prevents platelets from making thromboxane, a substance that facilitates clotting," Weilbaecher says.

Weilbaecher说：“阿斯匹林可以阻止血小板生成凝血恶烷，即一种可以促进凝血的物质。”

9.The role of thromboxane in platelet aggregation is crucial for wound healing.

血栓素在血小板聚集中的作用对伤口愈合至关重要。

10.Inhibiting thromboxane production can help reduce the risk of heart attacks.

抑制血栓素的产生可以帮助降低心脏病发作的风险。

11.Research shows that high levels of thromboxane are associated with various cardiovascular diseases.

研究表明，高水平的血栓素与各种心血管疾病相关。

12.Aspirin works by blocking the formation of thromboxane in the body.

阿司匹林通过阻止体内血栓素的形成来发挥作用。

13.Patients with elevated thromboxane levels may require closer monitoring.

血清中血栓素水平升高的患者可能需要更密切的监测。

作文

Thromboxane is a compound that plays a crucial role in the body's hemostatic processes. It is classified as a type of eicosanoid, which are signaling molecules derived from fatty acids. Specifically, thromboxane (血栓素) is produced by platelets during the process of blood clotting. When a blood vessel is injured, platelets aggregate at the site to form a plug, and in this process, they release various substances, including thromboxane (血栓素). This compound serves multiple functions; it promotes further platelet aggregation and vasoconstriction, which helps to reduce blood flow to the affected area and facilitates the formation of a stable blood clot. The synthesis of thromboxane (血栓素) occurs through the enzyme cyclooxygenase, which converts arachidonic acid into prostaglandins and thromboxanes. Among these, thromboxane (血栓素) A2 is the most significant form, as it is primarily responsible for the activation of platelets. The balance between thromboxanes and other eicosanoids, such as prostacyclin, is critical for maintaining normal cardiovascular function. While thromboxane (血栓素) promotes clot formation, prostacyclin has the opposite effect, inhibiting platelet aggregation and causing vasodilation. An imbalance in the production of thromboxane (血栓素) can lead to pathological conditions. For instance, excessive production of thromboxane (血栓素) may contribute to thrombotic disorders, where blood clots form excessively, potentially leading to heart attacks or strokes. Conversely, insufficient levels of thromboxane (血栓素) can impair the body's ability to stop bleeding, resulting in hemorrhagic complications. Therefore, understanding the role of thromboxane (血栓素) in hemostasis is vital for developing therapeutic strategies for various cardiovascular diseases. In clinical settings, medications that target the action of thromboxane (血栓素) are often used to prevent thrombosis. Aspirin, for example, irreversibly inhibits cyclooxygenase, thereby reducing the production of thromboxane (血栓素) A2 in platelets. This antiplatelet effect is beneficial for individuals at risk of cardiovascular events. However, the use of such medications must be carefully managed, as they can also increase the risk of bleeding due to their effects on hemostasis. Research continues to explore the multifaceted roles of thromboxane (血栓素) in health and disease. New studies have indicated that thromboxane (血栓素) may also have implications beyond hemostasis, including effects on inflammation and tissue repair. Understanding these additional roles could pave the way for novel therapeutic approaches in managing not just cardiovascular diseases but also other inflammatory conditions. In conclusion, thromboxane (血栓素) is a vital molecule in the regulation of blood clotting and vascular health. Its dual role as both a promoter of platelet aggregation and a mediator of vasoconstriction underscores its importance in maintaining hemostatic balance. Ongoing research into thromboxane (血栓素) will undoubtedly enhance our understanding of its complex biological functions and its potential as a therapeutic target in various diseases.

血栓素是一个在体内止血过程中起着关键作用的化合物。它被归类为一种类花生酸，属于从脂肪酸衍生的信号分子。具体来说，thromboxane（血栓素）是在血小板在血液凝固过程中产生的。当血管受伤时，血小板会聚集在受损部位形成一个堵塞，并在此过程中释放多种物质，包括thromboxane（血栓素）。该化合物具有多重功能；它促进进一步的血小板聚集和血管收缩，这有助于减少受影响区域的血流并促进稳定血块的形成。 thromboxane（血栓素）的合成是通过环氧合酶这一酶进行的，该酶将花生四烯酸转化为前列腺素和血栓素。在这些中，thromboxane（血栓素）A2是最重要的形式，因为它主要负责激活血小板。血栓素与其他类花生酸（如前列环素）之间的平衡对于维持正常的心血管功能至关重要。虽然thromboxane（血栓素）促进血块形成，但前列环素则具有相反的效果，抑制血小板聚集并导致血管扩张。 thromboxane（血栓素）产生的失衡可能导致病理状况。例如，过量产生thromboxane（血栓素）可能导致血栓性疾病，即血块过度形成，可能导致心脏病发作或中风。相反，thromboxane（血栓素）水平不足可能会损害身体止血的能力，导致出血并发症。因此，理解thromboxane（血栓素）在止血中的作用对于开发各种心血管疾病的治疗策略至关重要。 在临床环境中，针对thromboxane（血栓素）作用的药物常用于预防血栓形成。例如，阿司匹林通过不可逆地抑制环氧合酶，从而减少血小板中thromboxane（血栓素）A2的产生。这种抗血小板效应对处于心血管事件风险中的个体是有益的。然而，这类药物的使用必须谨慎管理，因为它们也可能由于对止血的影响而增加出血风险。 研究仍在继续探索thromboxane（血栓素）在健康和疾病中的多方面作用。新的研究表明，thromboxane（血栓素）可能还与炎症和组织修复等方面有关。理解这些额外角色可能为管理不仅仅是心血管疾病的其他炎症状况开辟新的治疗方法。 总之，thromboxane（血栓素）是调节血液凝固和血管健康的重要分子。它作为血小板聚集的促进剂和血管收缩介质的双重角色强调了其在维持止血平衡中的重要性。对thromboxane（血栓素）的持续研究无疑将增强我们对其复杂生物功能和作为各种疾病治疗靶点潜力的理解。