fibrinoid

简明释义

英[ˈfaɪbrɪnɔɪd]美[ˈfaɪbrəˌnɔɪd]

adj. 纤维蛋白样的

n. 类纤维蛋白

英英释义

单词用法

同义词

反义词

例句

1.Malignant hypertension leads to fibrinoid necrosis of small arteries as shown here. The damage to the arteries leads to formation of pink fibrin — hence the term "fibrinoid".

恶性高血压导致小动脉纤维素样坏死。动脉损伤引起粉红色纤维素坏死物形成，因此称为纤维素样坏死。

2.Malignant hypertension leads to fibrinoid necrosis of small arteries as shown here. The damage to the arteries leads to formation of pink fibrin — hence the term "fibrinoid".

恶性高血压导致小动脉纤维素样坏死。动脉损伤引起粉红色纤维素坏死物形成，因此称为纤维素样坏死。

3.They can occasionally appear in visceral organs. There is a central area of fibrinoid necrosis surrounded by pallisading epithelioid macrophages and other mononuclear cells.

结节中央为纤维素样坏死物，四周围绕着上皮样细胞与其它单核细胞。

4.Malignant hypertension leads to fibrinoid necrosis of small arteries as shown here.

恶性高血压导致小动脉纤维素样坏死。

5.The biopsy revealed the presence of fibrinoid deposits in the affected tissue.

活检显示受影响组织中存在纤维样沉积物。

6.In autoimmune diseases, fibrinoid necrosis can often be observed.

在自身免疫性疾病中，常常可以观察到纤维样坏死。

7.The pathologist noted that the fibrinoid change was indicative of a chronic inflammatory response.

病理学家指出，纤维样变化表明慢性炎症反应。

8.Samples showed extensive areas of fibrinoid material in the skin lesions.

样本显示皮肤损伤中有广泛的纤维样物质区域。

9.The study focused on the role of fibrinoid in vascular diseases.

该研究集中于纤维样在血管疾病中的作用。

作文

In the realm of medical science, the term fibrinoid refers to a substance that resembles fibrin, which is a protein involved in blood clotting. This term is often used in the context of pathological conditions where there is an abnormal deposition of fibrin-like material in tissues. Understanding fibrinoid changes can provide valuable insights into various diseases, particularly autoimmune disorders and vascular diseases. For instance, in conditions such as systemic lupus erythematosus, one may observe the presence of fibrinoid necrosis, where the tissue appears eosinophilic and amorphous due to the accumulation of this protein-like material. This phenomenon is indicative of underlying inflammation and tissue damage, which are hallmark features of many chronic diseases. The significance of fibrinoid deposits extends beyond mere observation; they serve as critical markers for diagnosing certain pathological states. In histological examinations, pathologists often look for these deposits to help differentiate between various types of vasculitis and other inflammatory processes. The identification of fibrinoid necrosis in blood vessels can point towards a specific type of immune-mediated injury, thereby guiding treatment options. Moreover, the study of fibrinoid changes has implications for understanding the mechanisms of disease progression. For example, in the context of atherosclerosis, the presence of fibrinoid materials in arterial walls can contribute to plaque formation and instability. This highlights the role of inflammation in cardiovascular diseases, where the accumulation of such proteins can lead to significant clinical outcomes, including heart attacks and strokes. In addition to its role in disease, fibrinoid also plays a part in normal physiological processes. During wound healing, the deposition of fibrin is crucial for forming a scaffold that allows tissue regeneration. However, when this process goes awry, excessive fibrinoid deposition can lead to complications such as fibrosis, where normal tissue is replaced with scar tissue, impairing function. Research continues to explore the various aspects of fibrinoid substances in both health and disease. Advances in immunohistochemistry and molecular biology allow for a deeper understanding of how these proteins interact with the immune system and contribute to pathology. As we uncover more about the role of fibrinoid in different contexts, it becomes increasingly evident that this term encapsulates a complex interplay between normal biological processes and pathological conditions. In conclusion, the term fibrinoid encompasses a wide range of meanings within the medical field, from its role in coagulation to its implications in various diseases. Recognizing the significance of fibrinoid changes not only aids in diagnosis but also enhances our understanding of disease mechanisms, paving the way for potential therapeutic interventions. As research progresses, the study of fibrinoid will undoubtedly continue to illuminate the intricate relationships between proteins, inflammation, and disease outcomes, ultimately contributing to better healthcare solutions for patients worldwide.

在医学科学领域，术语fibrinoid指的是一种类似于纤维蛋白的物质，纤维蛋白是一种参与血液凝固的蛋白质。这个术语通常用于病理条件下，在组织中出现异常的纤维蛋白样物质沉积。理解fibrinoid变化可以为各种疾病提供有价值的见解，特别是自身免疫疾病和血管疾病。例如，在系统性红斑狼疮等疾病中，可能会观察到fibrinoid坏死的存在，其组织由于这种蛋白质样物质的积累而呈现嗜酸性和无定形状。这种现象表明潜在的炎症和组织损伤，而这些是许多慢性疾病的标志特征。 fibrinoid沉积的重要性不仅仅在于观察；它们作为某些病理状态诊断的关键标志。在组织学检查中，病理学家常常寻找这些沉积物，以帮助区分各种类型的血管炎和其他炎症过程。在血管中识别fibrinoid坏死可能指向特定类型的免疫介导损伤，从而指导治疗选择。 此外，研究fibrinoid变化对理解疾病进展机制具有重要意义。例如，在动脉粥样硬化的背景下，动脉壁中fibrinoid物质的存在可能导致斑块形成和不稳定。这突显了炎症在心血管疾病中的作用，其中此类蛋白质的积聚可能导致显著的临床结果，包括心脏病发作和中风。 除了在疾病中的作用外，fibrinoid在正常生理过程中也发挥着作用。在伤口愈合过程中，纤维蛋白的沉积对于形成允许组织再生的支架至关重要。然而，当这一过程出现问题时，过度的fibrinoid沉积可能导致纤维化等并发症，即正常组织被瘢痕组织取代，从而影响功能。 研究继续探索fibrinoid物质在健康和疾病中的各个方面。免疫组化和分子生物学的进步使我们能够更深入地理解这些蛋白质如何与免疫系统相互作用以及如何导致病理变化。随着我们对fibrinoid在不同背景下作用的揭示，越来越明显的是，这个术语概括了正常生物过程与病理条件之间复杂的相互作用。 总之，术语fibrinoid在医学领域涵盖了广泛的含义，从其在凝血中的作用到其在各种疾病中的影响。认识到fibrinoid变化的重要性不仅有助于诊断，还增强了我们对疾病机制的理解，为潜在的治疗干预铺平了道路。随着研究的进展，对fibrinoid的研究无疑将继续阐明蛋白质、炎症和疾病结果之间错综复杂的关系，最终为全球患者提供更好的医疗解决方案。