atherogenesis

简明释义

英[ˌæθərəʊˈdʒenɪsɪs]美[ˌæθəroˈdʒenɪsɪs]

n. 动脉粥样化形成

复 数 a t h e r o g e n e s e s

英英释义

单词用法

同义词

反义词

例句

1.Conclusion BRF has dramatically reduced serum anti ox LDL antibody levels and this effect may be related to its anti atherogenesis.

这表明黑米皮的抗动脉粥样硬化作用可能与其降低抗氧化型低密度脂蛋白抗体水平有关。

2.Thus we now turn our attention to contemporary theories of atherogenesis.

因此，我们现在将注意力放在当代的动脉粥样化形成理论上。

3.We hypothesized that PARP may play an important role in atherogenesis and that its inhibition may attenuate atherosclerotic plaque development in an experimental model of atherosclerosis.

我们假设PARP可能在动脉粥样硬化形成中起重要作用，它的抑制可能会减弱动脉粥样硬化实验模型中动脉硬化斑块的进展。

4.There is increasing evidence that lipid peroxidation and oxidative modification of low density lipoprotein is important in atherogenesis.

脂质过氧化和低密度脂蛋白的氧化修饰在动脉硬化的发生中起着极其重要的作用。

5.Although some data from experimental models support a role of CRP in atherogenesis, its direct involvement remains in question.

尽管由实验模型得到的数据支持CRP在动脉粥样硬化形成中的作用，但它的直接关系仍在讨论中。

6.Does Infection Play a Role in Atherogenesis and Plaque Rupture?

动脉硬化与斑块破裂：感染是否在起作用？

7.During atherogenesis, vascular smooth muscle cells proliferate, migrate from tunica intima to media and uptake lipid then become foam cells.

我们推测动脉粥样硬化形成过程中血管平滑肌细胞能量代谢发生了改变。

8.The study focused on the mechanisms of atherogenesis 动脉粥样硬化形成 in patients with diabetes.

这项研究集中于糖尿病患者中动脉粥样硬化形成的机制。

9.Researchers are investigating how inflammation contributes to atherogenesis 动脉粥样硬化形成.

研究人员正在调查炎症如何促进动脉粥样硬化形成。

10.Dietary choices can significantly influence the rate of atherogenesis 动脉粥样硬化形成.

饮食选择可以显著影响动脉粥样硬化形成的速度。

11.High cholesterol levels are a known risk factor for atherogenesis 动脉粥样硬化形成.

高胆固醇水平是动脉粥样硬化形成的已知风险因素。

12.Exercise has been shown to reduce the risk of atherogenesis 动脉粥样硬化形成.

锻炼已被证明可以降低动脉粥样硬化形成的风险。

作文

Atherosclerosis is a condition that affects millions of people worldwide, leading to serious health issues such as heart attacks and strokes. At the heart of this condition is a process known as atherogenesis, which refers to the formation of fatty deposits in the arteries. Understanding atherogenesis is crucial for both prevention and treatment of cardiovascular diseases. The process of atherogenesis begins with damage to the endothelium, the thin layer of cells lining the blood vessels. Factors such as high blood pressure, smoking, and high cholesterol can contribute to this damage. Once the endothelium is compromised, it becomes more permeable, allowing lipoproteins, particularly low-density lipoprotein (LDL), to penetrate the arterial wall. As LDL cholesterol accumulates in the arterial wall, it undergoes oxidation, which triggers an inflammatory response. Immune cells, such as macrophages, are attracted to the site of injury and attempt to engulf the oxidized LDL. However, when these immune cells become overwhelmed, they transform into foam cells, which are a hallmark of atherogenesis. These foam cells accumulate and form fatty streaks within the arterial walls. Over time, the buildup of foam cells and other cellular debris leads to the development of plaques, which can narrow the arteries and reduce blood flow. This stage of atherogenesis is particularly dangerous, as plaques can rupture, causing blood clots that may block blood flow entirely. The consequences of such blockages can be dire, resulting in heart attacks or strokes. Preventing atherogenesis involves addressing the risk factors associated with the condition. Lifestyle changes such as adopting a heart-healthy diet, engaging in regular physical activity, and quitting smoking can significantly reduce the likelihood of developing atherosclerosis. Additionally, medical interventions, including medications to lower cholesterol levels and manage blood pressure, play a vital role in preventing the progression of atherogenesis. Research continues to explore the mechanisms underlying atherogenesis and potential therapeutic targets. Advances in our understanding of this process may lead to innovative treatments that can halt or even reverse the progression of atherosclerosis. For instance, studies are investigating the role of inflammation in atherogenesis and how anti-inflammatory drugs might mitigate its effects. In conclusion, atherogenesis is a critical factor in the development of cardiovascular diseases. By understanding its mechanisms and risk factors, individuals can take proactive steps to protect their heart health. Public health initiatives aimed at educating communities about the importance of lifestyle choices in preventing atherogenesis are essential. Ultimately, greater awareness and understanding of this process can lead to healthier lives and reduced rates of heart disease.

动脉粥样硬化是一种影响全球数百万人的疾病，导致严重的健康问题，如心脏病发作和中风。在这种疾病的核心是一个被称为动脉粥样硬化形成的过程，指的是脂肪沉积在动脉中的形成。理解动脉粥样硬化形成对预防和治疗心血管疾病至关重要。 动脉粥样硬化形成的过程始于内皮的损伤，即血管内壁的薄层细胞。这种损伤可能由高血压、吸烟和高胆固醇等因素引起。一旦内皮受损，它就变得更具通透性，允许脂蛋白，特别是低密度脂蛋白（LDL），渗透到动脉壁中。 随着LDL胆固醇在动脉壁中的积累，它会发生氧化，触发炎症反应。免疫细胞，如巨噬细胞，会被吸引到损伤部位，试图吞噬氧化的LDL。然而，当这些免疫细胞不堪重负时，它们会转变为泡沫细胞，这是动脉粥样硬化形成的一个标志。这些泡沫细胞会积聚并在动脉壁内形成脂肪条纹。 随着时间的推移，泡沫细胞和其他细胞碎片的积累导致斑块的形成，这会使动脉狭窄并减少血流。这一阶段的动脉粥样硬化形成尤其危险，因为斑块可能破裂，导致血栓完全阻塞血流。这种阻塞的后果可能是严重的，导致心脏病发作或中风。 预防动脉粥样硬化形成涉及解决与该病相关的风险因素。生活方式的改变，例如采用健康的饮食、定期锻炼和戒烟，可以显著降低发展动脉粥样硬化的可能性。此外，医疗干预，包括降低胆固醇水平和控制血压的药物，在预防动脉粥样硬化形成的进展中发挥着至关重要的作用。 研究继续探索动脉粥样硬化形成的机制和潜在治疗靶点。我们对这一过程的理解的进步可能会导致创新治疗方法，可以停止甚至逆转动脉粥样硬化的进展。例如，研究正在调查炎症在动脉粥样硬化形成中的作用，以及抗炎药物如何可能减轻其影响。 总之，动脉粥样硬化形成是心血管疾病发展的关键因素。通过理解其机制和风险因素，个人可以采取积极措施来保护他们的心脏健康。旨在教育社区关于生活方式选择在预防动脉粥样硬化形成中的重要性的公共卫生倡议是必不可少的。最终，对这一过程的更大意识和理解可以导致更健康的生活和降低心脏病的发生率。