avidin

简明释义

英[ˈævɪdɪn]美[ævədɪn]

n. [生化] 抗生物素蛋白；[生化] 卵白素；亲和素

英英释义

单词用法

同义词

反义词

例句

1.Methods Immunohistochemistry was performed by using avidin-biotin peroxidase complex procedure.

方法采用链霉素抗生物素蛋白生物素过氧化物酶免疫组织化学染色。

2.Bycomparing different chemical methods for the immobilization of aptamer, biotin-avidin method was finally chosen.

通过对比不同化学固定方式，选择亲和素-生物素法作为适配子探针的固定方法。

3.Objective: To determine the activity of avidin in hens egg white power after heat treatment.

目的：了解经过一定温度处理的蛋清粉中抗生物素蛋白的活性。

4.The receptive group can be an antibody, a fragment of an antibody, an avidin, a streptavidin, or a biotin moiety.

该接受基团可以是抗体、抗体片段、抗生物素蛋白、链霉抗生物素蛋白、或生物素基序。

5.Methods: Immunohistochemical staining was performed in various types of stomach cancer by a standard avidin-biotin-peroxidase (ABC) technique.

方法：用免疫组化abc法，对不同类型胃癌进行对比检查。

6.Objective To explore the diagnostic efficiency of circulating antigen using the TM5. 28 mAB-biotin-avidin system for the detection of schistosomiasis japonica.

目的探讨TM5．28单克隆抗体-生物素-亲和素系统检测日本血吸虫循环抗原及其诊断效果。

7.Labelled avidin-biotin-ELISA (LAB-ELISA) was established to detect pre-S proteins in serum, and it is verified that specificity of this technique is fairly high as compared with control experiments.

采用本室建立的标记抗生物素-生物素酶联免疫试验及间接酶免疫试验进行血清与肝组织前S蛋白检测。

8.The research team used avidin to purify the biotinylated proteins from the cell lysate.

研究小组使用avidin从细胞裂解液中纯化生物素化蛋白。

9.In the lab, avidin is often employed in assays to detect biotinylated molecules.

在实验室中，avidin常用于检测生物素化分子的检测中。

10.The binding affinity of avidin for biotin is one of the strongest known in nature.

avidin与生物素的结合亲和力是自然界中已知最强的结合之一。

11.Researchers labeled the antibodies with avidin to enhance their visibility in imaging studies.

研究人员用avidin标记抗体，以增强其在成像研究中的可见性。

12.The use of avidin in the experiment allowed for a more accurate measurement of the target protein.

在实验中使用avidin使目标蛋白的测量更加准确。

作文

In the realm of biochemistry, there are numerous proteins that play significant roles in various biological processes. One such protein is avidin, a glycoprotein that is primarily found in egg whites. It has garnered much attention due to its unique ability to bind biotin, a crucial vitamin that is essential for many metabolic processes in living organisms. The binding affinity between avidin and biotin is extraordinarily high, making it one of the strongest non-covalent interactions known in nature. This characteristic has led to the utilization of avidin in various scientific applications, particularly in molecular biology and biotechnology. The discovery of avidin dates back to the early 20th century when scientists began to explore the properties of egg white proteins. Research has shown that avidin can bind up to four molecules of biotin, forming a stable complex that is resistant to changes in temperature and pH. This stability is a significant advantage in laboratory settings where conditions may vary. Moreover, the avidin-biotin interaction is used extensively in techniques such as immunohistochemistry, where it helps in detecting specific proteins within cells or tissues. One of the fascinating aspects of avidin is its role in the development of diagnostic tools. By attaching biotinylated antibodies to avidin, researchers can create highly sensitive assays that detect minute quantities of antigens. This application is particularly valuable in clinical diagnostics, where early detection of diseases can significantly improve treatment outcomes. Furthermore, the avidin-biotin system is also employed in gene expression studies, allowing scientists to visualize and quantify the presence of specific RNA molecules. Despite its many benefits, the use of avidin is not without challenges. For example, while it is a powerful tool in research, the presence of avidin in certain foods, particularly raw egg whites, can lead to biotin deficiency if consumed in large amounts over time. This is because avidin binds biotin in the intestine, preventing its absorption. However, cooking egg whites denatures avidin, rendering it unable to bind biotin and thus making it safe to consume. In conclusion, avidin is a remarkable protein with a wide array of applications in science and medicine. Its ability to bind biotin with high affinity has made it an indispensable tool in various research fields, including molecular biology and diagnostics. Understanding the properties and functions of avidin not only enhances our knowledge of biochemistry but also opens up new avenues for innovative research and therapeutic strategies. As we continue to explore the complexities of proteins like avidin, we unlock the potential for advancements in health and technology that can benefit society as a whole.

在生物化学领域，有许多蛋白质在各种生物过程中发挥着重要作用。其中一种蛋白质是avidin，这是一种主要存在于蛋清中的糖蛋白。由于其独特的结合生物素的能力，它引起了广泛的关注，生物素是一种对许多代谢过程至关重要的维生素。avidin与生物素之间的结合亲和力极高，使其成为自然界中已知的最强非共价相互作用之一。这一特性使得avidin在分子生物学和生物技术等科学应用中得到了广泛的利用。 avidin的发现可以追溯到20世纪初，当时科学家们开始探索蛋白质的性质。研究表明，avidin可以结合多达四个生物素分子，形成一个稳定的复合物，该复合物对温度和pH变化具有抵抗力。这种稳定性在实验室环境中是一个显著的优势，因为条件可能会有所变化。此外，avidin-生物素相互作用在免疫组织化学等技术中被广泛应用，有助于检测细胞或组织内特定蛋白质。 avidin的一个迷人之处在于它在诊断工具开发中的作用。通过将生物素化抗体附加到avidin上，研究人员可以创建高度敏感的检测方法，检测微量抗原。这一应用在临床诊断中尤为宝贵，因为早期发现疾病可以显著改善治疗结果。此外，avidin-生物素系统还用于基因表达研究，使科学家能够可视化和量化特定RNA分子的存在。 尽管有许多好处，但使用avidin也并非没有挑战。例如，虽然它在研究中是一种强大的工具，但某些食物（特别是生蛋白）中avidin的存在，如果大量食用，可能导致生物素缺乏。这是因为avidin在肠道中结合生物素，阻止其吸收。然而，烹饪蛋白会使avidin变性，从而使其无法结合生物素，因此安全可食用。 总之，avidin是一种具有广泛应用的卓越蛋白质，尤其是在科学和医学领域。其与生物素的高亲和力使其成为各种研究领域（包括分子生物学和诊断）中不可或缺的工具。理解avidin的性质和功能不仅增强了我们对生物化学的知识，也为创新研究和治疗策略开辟了新的途径。随着我们继续探索像avidin这样的蛋白质的复杂性，我们将解锁健康和技术进步的潜力，从而使整个社会受益。