azidothymidine

简明释义

英[/ˌeɪ.zaɪ.doʊˈθaɪ.mɪ.din/]美[/ˌeɪ.zaɪ.doʊˈθaɪ.mɪ.din/]

n. 叠氮胸苷

英英释义

单词用法

同义词

反义词

例句

1.Objective To investigate the degradation pharmacokinetics of azidothymidine palmitate and azidothymidine palmitate liposomes in different homogenate of mice.

目的考察齐多夫定棕榈酸酯及其脂质体在小鼠各组织中的降解动力学。

2.Objective To investigate the degradation pharmacokinetics of azidothymidine palmitate and azidothymidine palmitate liposomes in different homogenate of mice.

目的考察齐多夫定棕榈酸酯及其脂质体在小鼠各组织中的降解动力学。

3.The drug azidothymidine is often used in the treatment of HIV infections.

药物azidothymidine通常用于治疗HIV感染。

4.Researchers are studying the effectiveness of azidothymidine in combination therapies.

研究人员正在研究azidothymidine在联合疗法中的有效性。

5.Patients taking azidothymidine need to be monitored for side effects.

服用azidothymidine的患者需要监测副作用。

6.The development of azidothymidine marked a significant milestone in antiviral therapy.

azidothymidine的开发标志着抗病毒治疗的重要里程碑。

7.Healthcare providers often prescribe azidothymidine as part of an antiretroviral regimen.

医疗提供者通常将azidothymidine作为抗逆转录病毒方案的一部分开处方。

作文

In the field of medicine, particularly in the treatment of HIV/AIDS, the drug azidothymidine plays a crucial role. Azidothymidine, also known as AZT, was one of the first antiretroviral drugs approved for use in HIV-infected patients. It belongs to a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs), which work by inhibiting the action of reverse transcriptase, an enzyme critical for the replication of HIV. This mechanism prevents the virus from multiplying and helps to manage the infection more effectively. The discovery of azidothymidine marked a significant breakthrough in the fight against HIV/AIDS. Before its introduction in the mid-1980s, there were limited options available to treat this devastating disease. Patients diagnosed with HIV faced a grim prognosis, and the lack of effective treatments led to high mortality rates. The development of azidothymidine provided hope to many individuals and families affected by the virus. However, the use of azidothymidine is not without its challenges. While it can effectively reduce the viral load in patients, long-term use of the drug can lead to side effects, including nausea, fatigue, and, in some cases, more severe complications such as bone marrow suppression. These side effects necessitate careful monitoring and management by healthcare providers. Moreover, the emergence of drug-resistant strains of HIV has posed additional challenges in the treatment landscape. Some patients may develop resistance to azidothymidine, making it less effective over time. As a result, researchers have been working tirelessly to develop new antiretroviral therapies that can be used in combination with azidothymidine or as alternatives to it. This ongoing research is crucial in the effort to provide effective treatment options for all patients living with HIV/AIDS. In addition to its medical significance, azidothymidine also represents a symbol of hope and resilience for the millions of people affected by HIV/AIDS worldwide. The drug's development reflects the dedication of scientists, healthcare professionals, and advocates who have worked tirelessly to improve the lives of those living with the virus. It underscores the importance of continued research and investment in the fight against infectious diseases. In conclusion, azidothymidine is more than just a pharmaceutical compound; it is a lifeline for many individuals battling HIV/AIDS. Its introduction revolutionized the treatment landscape and opened the door for further advancements in antiretroviral therapy. While challenges remain, the legacy of azidothymidine serves as a reminder of the progress made in medicine and the ongoing commitment to improving health outcomes for all patients. As we move forward, it is vital to continue supporting research and access to treatment for those affected by HIV/AIDS, ensuring that the lessons learned from the past inform our efforts for a healthier future.

在医学领域，特别是在HIV/AIDS的治疗中，药物azidothymidine发挥着至关重要的作用。azidothymidine，也被称为AZT，是第一个获得批准用于HIV感染患者的抗逆转录病毒药物之一。它属于核苷类逆转录酶抑制剂（NRTIs）的一类药物，通过抑制逆转录酶的作用来发挥作用，而逆转录酶是HIV复制过程中关键的酶。这种机制可以阻止病毒的繁殖，并帮助更有效地控制感染。 azidothymidine的发现标志着对抗HIV/AIDS斗争中的重大突破。在20世纪80年代中期，它的引入之前，治疗这种毁灭性疾病的选择非常有限。被诊断为HIV的患者面临着严峻的预后，缺乏有效的治疗导致了高死亡率。azidothymidine的开发为许多受病毒影响的个人和家庭带来了希望。 然而，使用azidothymidine并非没有挑战。虽然它可以有效降低患者的病毒载量，但长期使用该药物可能会导致副作用，包括恶心、疲劳，以及在某些情况下，骨髓抑制等更严重的并发症。这些副作用需要医疗提供者进行仔细监测和管理。 此外，HIV耐药株的出现给治疗领域带来了额外的挑战。一些患者可能对azidothymidine产生耐药性，从而使其随着时间的推移变得不那么有效。因此，研究人员一直在不懈努力开发新的抗逆转录病毒疗法，可以与azidothymidine联合使用或作为替代方案。这项持续的研究对于为所有HIV/AIDS患者提供有效的治疗选择至关重要。 除了其医学意义外，azidothymidine还代表着全球数百万受HIV/AIDS影响的人的希望和韧性。这种药物的开发反映了科学家、医疗专业人员和倡导者的不懈努力，他们一直在努力改善生活在这种病毒中的人们的生活。它强调了继续研究和投资于抗传染病斗争的重要性。 总之，azidothymidine不仅仅是一种药物化合物；它是许多与HIV/AIDS作斗争的个体的生命线。它的引入彻底改变了治疗领域，并为抗逆转录病毒疗法的进一步进展打开了大门。尽管挑战仍然存在，但azidothymidine的遗产提醒我们在医学上取得的进展以及对改善所有患者健康结果的持续承诺。在未来，我们必须继续支持研究和治疗的可及性，以确保从过去学到的教训为我们努力实现更健康的未来提供指导。