benzodiazepine

简明释义

英[ˌbɛnzoʊˈdaɪəˌzɛpiːn]美[ˌbɛnzoʊˈdaɪəˌzɛpiːn]

n. 苯二氮（用于制造各种镇静药）

英英释义

单词用法

同义词

反义词

例句

1.OBJECTIVE:To summarize the aspect of the research work and clinical application of non-benzodiazepine sedative hypnotic drugs, and reflect the progress of this kind of drugs.

目的：评价非苯二氮类催眠药作用研究和临床应用，反映催眠药进展的侧面。

2.Clorazepate is a benzodiazepine.

氯氮是一种苯二氮卓类药物。

3.A screening analytical method for 11 benzodiazepine medicines and 9 their main metabolites in plasma and urine using electron capture detection gas chromatography was developed.

建立了血浆和尿中11种苯并二氮杂类药物及其9种代谢物的电子捕获检测气相色谱分析方法。

4.Part II: 1h-1, 5-benzodiazepine are interesting compounds because of their pharmacological properties and biological activity.

第二部分：1,5 -苯二嗪类化合物具有独特的药理及生理活性。

5.Another change is the rise of tranquillisers such as benzodiazepine and diazepam.

另一变化是苯二氮和安定一类的镇静剂的使用也在增加。

6.The most well-known sleeping pills are the non-benzodiazepine hypnotics like Ambien, Lunesta or Sonata. These drugs affect structures in the brain called GABA receptors.

最有名的安眠药是像安必恩，卢内思塔，或松那塔这类的非苯二氮类催眠药，作用在人脑中称为GABA受体的组织上。

7.Objective To determine the efficacy and safety of trazodone in the treatment of benzodiazepine withdrawal symptoms.

目的验证曲唑酮对苯二氮类药物戒断症状的疗效及安全性。

8.In 1956 Mr Sternbach, fiddling with yet another benzodiazepine, treated it with methylamine, made a white crystalline powder, labelled it Ro 5-0690 and put it away on a shelf.

1956年，施特恩巴赫在胡乱处理一种苯二氮卓类化合物的时候，用甲胺化合制成了一种白色晶状粉末，标上"Ro5"06卯"放在了架子上。

9.The doctor prescribed a low dose of benzodiazepine for my anxiety.

医生开了一剂低剂量的苯二氮平来缓解我的焦虑。

10.Many people use benzodiazepine to help them sleep better at night.

许多人使用苯二氮平来帮助他们晚上更好地入睡。

11.Long-term use of benzodiazepine can lead to dependence.

长期使用苯二氮平可能会导致依赖。

12.It's important to follow the prescribed dosage of benzodiazepine to avoid side effects.

遵循处方剂量使用苯二氮平以避免副作用是很重要的。

13.Some patients experience withdrawal symptoms when stopping benzodiazepine suddenly.

一些患者在突然停止使用苯二氮平时会经历戒断症状。

作文

Benzodiazepines are a class of medications that are widely used in the treatment of various conditions, primarily anxiety, insomnia, and seizures. They work by enhancing the effect of a neurotransmitter in the brain called gamma-aminobutyric acid (GABA). This action results in a calming effect on the nervous system, making them effective for individuals who struggle with anxiety disorders or sleep disturbances. One of the most notable characteristics of benzodiazepines is their ability to provide rapid relief from symptoms, which is why they are often prescribed for short-term use. However, despite their effectiveness, there are significant concerns regarding their long-term use and potential for dependence. The history of benzodiazepines dates back to the 1960s when they were first introduced as a safer alternative to barbiturates. Barbiturates were widely used at the time but had a high potential for overdose and addiction. In contrast, benzodiazepines offered a better safety profile, leading to their rapid adoption in clinical practice. Medications such as diazepam (Valium) and lorazepam (Ativan) became household names, synonymous with anxiety relief and sedation. However, as the years passed, healthcare professionals began to recognize the drawbacks associated with benzodiazepines. One of the primary concerns is the risk of developing tolerance, where patients require higher doses to achieve the same therapeutic effect. This can lead to a cycle of increasing dosage and potential dependency. Furthermore, abrupt discontinuation of benzodiazepines can result in withdrawal symptoms, which can be severe and uncomfortable. In addition to the risk of addiction, benzodiazepines can also have side effects that impact daily functioning. Common side effects include drowsiness, dizziness, and impaired coordination, which can increase the risk of falls, particularly in older adults. There is also evidence suggesting that long-term use of benzodiazepines may be associated with cognitive decline and memory impairment, raising concerns about their safety in the aging population. Given these risks, many healthcare providers are now more cautious when prescribing benzodiazepines. They often recommend non-pharmacological approaches to manage anxiety and insomnia, such as cognitive-behavioral therapy (CBT) or mindfulness practices. When benzodiazepines are deemed necessary, they are typically prescribed for the shortest duration possible and at the lowest effective dose. In conclusion, while benzodiazepines play a crucial role in the management of anxiety and related disorders, it is vital for both patients and healthcare providers to approach their use with caution. Understanding the benefits and risks associated with benzodiazepines can help ensure that they are used safely and effectively, minimizing the potential for dependence and adverse effects. As research continues, it is essential to stay informed about the best practices for using these medications, balancing the need for relief with the responsibility of safeguarding health and well-being.

苯二氮平类药物是一类广泛用于治疗各种疾病的药物，主要包括焦虑、失眠和癫痫发作。它们通过增强大脑中一种叫做γ-氨基丁酸（GABA）的神经递质的作用来发挥效果。这种作用导致神经系统的镇静效果，使其对那些挣扎于焦虑症或睡眠障碍的人有效。苯二氮平类药物最显著的特征之一是它们能够迅速缓解症状，这就是为什么它们通常被处方用于短期使用。然而，尽管它们有效，但长期使用和依赖的潜在问题引起了重大关注。 苯二氮平类药物的历史可以追溯到20世纪60年代，当时它们首次作为巴比妥类药物的安全替代品被引入。那时，巴比妥类药物被广泛使用，但有很高的过量和成瘾潜力。相比之下，苯二氮平类药物提供了更好的安全性，因此迅速被临床采用。像地西泮（Valium）和劳拉西泮（Ativan）这样的药物成为家喻户晓的名字，与焦虑缓解和镇静同义。 然而，随着时间的推移，医疗专业人士开始认识到与苯二氮平类药物相关的缺点。主要的担忧之一是耐药性的风险，即患者需要更高的剂量才能达到相同的治疗效果。这可能导致剂量增加和潜在依赖的循环。此外，突然停止使用苯二氮平类药物可能会导致戒断症状，这些症状可能是严重和不适的。 除了成瘾风险外，苯二氮平类药物还可能有影响日常功能的副作用。常见的副作用包括嗜睡、头晕和协调能力受损，这可能会增加跌倒的风险，特别是在老年人中。还有证据表明，长期使用苯二氮平类药物可能与认知衰退和记忆障碍相关，引发了对其在老年人群体中安全性的担忧。 鉴于这些风险，许多医疗提供者在开处方苯二氮平类药物时变得更加谨慎。他们通常建议采用非药物的方法来管理焦虑和失眠，例如认知行为疗法（CBT）或正念练习。当认为有必要使用苯二氮平类药物时，通常会以尽可能短的时间和最低有效剂量进行处方。 总之，虽然苯二氮平类药物在管理焦虑及相关疾病中发挥着至关重要的作用，但患者和医疗提供者都必须谨慎对待其使用。理解苯二氮平类药物的益处和风险可以帮助确保它们安全有效地使用，最大限度地减少依赖和不良反应的潜力。随着研究的继续，保持对使用这些药物最佳实践的了解至关重要，以平衡缓解需求与保护健康和福祉的责任。