butyrate

简明释义

英[ˈbjuːtɪˌreɪt]美[ˈbjʊtəˌreɪt]

n. [有化] 丁酸盐

英英释义

单词用法

同义词

反义词

例句

1.Glycidol butyrate is an important chiral material and synthetic intermediate.

缩水甘油丁酸酯是一种重要的手性原料和合成中间体。

2.A new method for the synthesis of benzyl n -butyrate with benzyl chloride and sodium n-butyrate by the catalyst of CTMAB is described.

以C TMAB为相转移催化剂， 氯化苄和丁酸钠为原料合成丁酸的新方法。

3.Objective: Synthesis of (r) -glycidyl butyrate was monitored by gas chromatography.

目的：建立气相色谱法监测(R)缩水甘油丁酸酯的合成。

4.Objective To investigate the effect of sodium butyrate on the appearance and bionomics of colon cancer line HT-29.

目的观察丁酸钠对结肠癌HT-29细胞形态和生物学特性的影响。

5.Objective To study the differentiation of human glioma cells BT-325 induced by sodium butyrate in vitro.

目的研究丁酸钠体外诱导人脑多型性胶质母细胞瘤细胞系BT- 325细胞的分化。

6.Differentiation was induced by sodium butyrate.

用丁酸钠诱导其分化。

7.The fermentation of dietary fibers in the gut produces short-chain fatty acids, including butyrate, which is essential for colon health.

膳食纤维在肠道中的发酵产生短链脂肪酸，包括丁酸盐，这对结肠健康至关重要。

8.Recent studies suggest that butyrate may have anti-inflammatory properties.

最近的研究表明，丁酸盐可能具有抗炎特性。

9.In animal models, butyrate has been shown to improve gut barrier function.

在动物模型中，丁酸盐已被证明可以改善肠道屏障功能。

10.Certain probiotics can increase the production of butyrate in the intestines.

某些益生菌可以增加肠道中丁酸盐的产生。

11.The presence of butyrate in the colon is linked to a lower risk of colorectal cancer.

结肠中丁酸盐的存在与结直肠癌风险降低有关。

作文

The human gut is home to trillions of microorganisms that play a crucial role in our overall health. Among these microorganisms, certain bacteria are known to produce short-chain fatty acids (SCFAs) through the fermentation of dietary fibers. One of the most important SCFAs is butyrate, which has garnered significant attention due to its numerous health benefits. In this essay, I will explore the role of butyrate in gut health, its sources, and its potential therapeutic effects on various diseases. Firstly, butyrate is primarily produced by the fermentation of dietary fibers by beneficial gut bacteria, particularly those from the Firmicutes phylum. Foods rich in fiber, such as fruits, vegetables, whole grains, and legumes, serve as substrates for these bacteria, promoting their growth and activity. As a result, a diet high in fiber not only supports the production of butyrate but also contributes to a diverse and balanced gut microbiome. The significance of butyrate lies in its role as a primary energy source for colonocytes, the cells lining the colon. These cells rely on butyrate for energy, which helps maintain the integrity of the intestinal barrier. A healthy intestinal barrier is crucial for preventing the translocation of harmful substances into the bloodstream, thus reducing the risk of inflammation and infection. Moreover, butyrate possesses anti-inflammatory properties that can benefit individuals suffering from various gastrointestinal disorders, such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). Research has shown that butyrate can help regulate immune responses in the gut, thereby reducing inflammation and promoting healing. This makes it a potential therapeutic agent for managing chronic inflammatory conditions. In addition to its effects on gut health, butyrate has been linked to several other health benefits. Studies have suggested that it may play a role in metabolic health by improving insulin sensitivity and regulating glucose metabolism. This is particularly relevant in the context of obesity and type 2 diabetes, where systemic inflammation and insulin resistance are prevalent. By enhancing the body’s ability to manage blood sugar levels, butyrate could potentially aid in the prevention and management of these metabolic disorders. Furthermore, emerging research indicates that butyrate may have protective effects against certain types of cancer. Specifically, it has been shown to inhibit the growth of colorectal cancer cells and induce apoptosis, or programmed cell death, in these cells. The mechanisms behind this effect are still being studied, but it highlights the importance of butyrate in cancer prevention and treatment strategies. To harness the benefits of butyrate, individuals can focus on incorporating more fiber-rich foods into their diets. Additionally, prebiotics and probiotics can support the growth of beneficial gut bacteria that produce butyrate. Fermented foods, such as yogurt, kefir, and sauerkraut, can also contribute to a healthy gut microbiome. In conclusion, butyrate is a vital short-chain fatty acid with profound implications for gut health and overall well-being. Its role in maintaining the intestinal barrier, regulating inflammation, and promoting metabolic health underscores the importance of a fiber-rich diet. As research continues to unfold, butyrate may emerge as a key player in the prevention and management of various diseases, making it essential for individuals to prioritize their gut health through dietary choices.

人类肠道中寄居着数万亿微生物，这些微生物在我们的整体健康中发挥着关键作用。在这些微生物中，某些细菌通过发酵膳食纤维产生短链脂肪酸（SCFAs），而其中最重要的短链脂肪酸之一是丁酸盐，由于其众多健康益处而受到广泛关注。在这篇文章中，我将探讨丁酸盐在肠道健康中的作用、来源及其对各种疾病的潜在治疗效果。 首先，丁酸盐主要是由有益肠道细菌，特别是来自厚壁菌门的细菌，通过发酵膳食纤维产生的。富含纤维的食物，如水果、蔬菜、全谷物和豆类，为这些细菌提供了底物，促进它们的生长和活性。因此，高纤维饮食不仅支持丁酸盐的生成，还促进了多样化和平衡的肠道微生物群。 丁酸盐的重要性在于它作为结肠细胞的主要能量来源。这些细胞依赖于丁酸盐获取能量，从而帮助维持肠道屏障的完整性。健康的肠道屏障对于防止有害物质转移到血液中至关重要，从而降低炎症和感染的风险。 此外，丁酸盐具有抗炎特性，可以惠及患有各种胃肠疾病的人，如炎症性肠病（IBD）和肠易激综合症（IBS）。研究表明，丁酸盐可以帮助调节肠道中的免疫反应，从而减少炎症并促进愈合。这使它成为管理慢性炎症状况的潜在治疗剂。 除了对肠道健康的影响外，丁酸盐还与其他几种健康益处相关联。研究表明，它可能在代谢健康中发挥作用，通过改善胰岛素敏感性和调节葡萄糖代谢。这在肥胖和2型糖尿病的背景下尤为相关，因为这些疾病中普遍存在全身性炎症和胰岛素抵抗。通过增强身体管理血糖水平的能力，丁酸盐可能有助于预防和管理这些代谢疾病。 此外，最新研究表明，丁酸盐可能对某些类型的癌症具有保护作用。具体而言，它已被证明可以抑制结直肠癌细胞的生长，并诱导这些细胞的凋亡，即程序性细胞死亡。这种效应背后的机制仍在研究中，但这突显了丁酸盐在癌症预防和治疗策略中的重要性。 为了利用丁酸盐的好处，个人可以专注于在饮食中增加更多富含纤维的食物。此外，益生元和益生菌可以支持产生丁酸盐的有益肠道细菌的生长。发酵食品，如酸奶、开菲尔和酸菜，也可以促进健康的肠道微生物群。 总之，丁酸盐是一种重要的短链脂肪酸，对肠道健康和整体福祉具有深远的影响。它在维持肠道屏障、调节炎症和促进代谢健康方面的作用突显了高纤维饮食的重要性。随着研究的不断深入，丁酸盐可能会成为预防和管理各种疾病的关键角色，因此个人应通过饮食选择优先考虑肠道健康。