calmodulin

简明释义

英[kəlˈmɒdjʊlɪn]美[kælˈmɑːdʒəˌlɪn;kælˈmɑːdʒuˌlɪ

n. [生化] 钙调蛋白；携钙素

英英释义

单词用法

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反义词

例句

1.Objective To study if calmodulin antagonist has anticonvulsant activity, and to provide theoretical evidence for exploring new anticonvulsant drug to improve clinical epilepsy therapy.

目的了解钙调素拮抗剂有无抗痫作用，为临床上开发新型的抗痫药以进一步控制癫痫提供理论依据。

2.In the modified calmodulin, they led to a completely new protein structure.

在重组钙调素蛋白中，他们他们创造了一种从来没有过的新的结构。

3.Calmodulin-like CML proteins also exist in plants, but their functions at the physiological and molecular levels are largely unknown. In this report, we present data on OsMSR2 Oryza sativa l.

植物中也存在着类钙调素(cml)蛋白，但是它们的生理和分子功能还不是很清楚。

4.FPZ fluorescence showed that the cellular calmodulin distributions were less than that of control after treatment of calmodulin antagonists.

利用FPZ作为荧光染色剂发现，经过钙调素拮抗剂处理的藻体有较低的钙调素分布。

5.Calmodulin-like CML proteins also exist in plants, but their functions at the physiological and molecular levels are largely unknown. In this report, we present data on OsMSR2 Oryza sativa l.

植物中也存在着类钙调素(cml)蛋白，但是它们的生理和分子功能还不是很清楚。

6.CDPK(Ca2+-dependent, calmodulin independent protein kinase) is the crucial protein kinase in plant calcium signal transduction, and play important role in osmotic stresses.

是植物钙信号传导过程中关键的蛋白激酶，在逆境胁迫信号传导过程中起到重要作用。

7.The binding of calcium ions to calmodulin leads to a conformational change that activates various target proteins.

钙离子与钙调素结合会导致构象变化，从而激活多种靶蛋白。

8.In muscle contraction, calmodulin plays a crucial role by regulating the activity of myosin light-chain kinase.

在肌肉收缩中，钙调素通过调节肌球蛋白轻链激酶的活性发挥关键作用。

9.Researchers discovered that calmodulin is involved in signal transduction pathways in neurons.

研究人员发现，钙调素参与神经元中的信号转导通路。

10.The interaction between calmodulin and its target proteins is essential for calcium signaling.

与其靶蛋白的相互作用对于钙信号传导至关重要。

11.Calmodulin is known to regulate various enzymes, including those involved in metabolism.

钙调素已知调节多种酶，包括参与代谢的酶。

作文

Calmodulin is a crucial protein found in all eukaryotic cells, playing a significant role in various cellular processes. This small protein, which binds calcium ions, acts as a calcium sensor and mediator for many signaling pathways. Understanding calmodulin (钙调蛋白) is essential for comprehending how cells respond to changes in their environment, particularly in relation to calcium levels. Calcium ions are vital for numerous physiological functions, including muscle contraction, neurotransmitter release, and cell division. When calcium levels rise, calmodulin (钙调蛋白) binds to these ions, causing a conformational change that allows it to interact with various target proteins. This interaction can activate or inhibit the target proteins, thereby influencing several cellular functions. For instance, in muscle cells, the binding of calcium to calmodulin (钙调蛋白) leads to the activation of myosin light chain kinase, which is essential for muscle contraction. Moreover, calmodulin (钙调蛋白) is involved in regulating enzyme activities, gene expression, and other cellular responses. It interacts with kinases, phosphatases, and other enzymes, modulating their activities in response to calcium fluctuations. This ability to act as a mediator between calcium signaling and various cellular functions makes calmodulin (钙调蛋白) a critical component in the intricate network of cellular signaling. Research has shown that alterations in calmodulin (钙调蛋白) function can lead to various diseases. For example, mutations in the calmodulin (钙调蛋白) gene have been linked to cardiac arrhythmias and other cardiovascular diseases. These findings highlight the importance of calmodulin (钙调蛋白) not only in normal cellular function but also in the pathogenesis of certain medical conditions. In addition to its role in health, calmodulin (钙调蛋白) has been studied for its potential applications in biotechnology and medicine. By understanding how calmodulin (钙调蛋白) interacts with various proteins, researchers can develop targeted therapies for diseases linked to calcium signaling dysregulation. Furthermore, calmodulin (钙调蛋白) can be utilized in biosensors to detect calcium levels in biological samples, providing valuable information for both research and clinical diagnostics. In conclusion, calmodulin (钙调蛋白) is a vital protein that plays a key role in calcium signaling and cellular regulation. Its ability to mediate various physiological processes underscores its importance in maintaining cellular homeostasis. The study of calmodulin (钙调蛋白) not only enhances our understanding of fundamental biological mechanisms but also holds promise for advancing medical science and therapeutic interventions. As research continues to uncover the complexities of calmodulin (钙调蛋白) and its interactions, we move closer to unlocking new possibilities for treating diseases and improving human health.

钙调蛋白是所有真核细胞中一种重要的蛋白质，在各种细胞过程中发挥着重要作用。这种小型蛋白质结合钙离子，作为钙传感器和许多信号通路的介导者。理解calmodulin（钙调蛋白）对理解细胞如何响应环境变化至关重要，特别是在与钙水平相关的方面。 钙离子对许多生理功能至关重要，包括肌肉收缩、神经递质释放和细胞分裂。当钙水平升高时，calmodulin（钙调蛋白）会与这些离子结合，导致构象变化，使其能够与各种靶蛋白相互作用。这种相互作用可以激活或抑制靶蛋白，从而影响多个细胞功能。例如，在肌肉细胞中，钙与calmodulin（钙调蛋白）的结合导致肌球蛋白轻链激酶的激活，这是肌肉收缩所必需的。 此外，calmodulin（钙调蛋白）还参与调节酶活性、基因表达和其他细胞反应。它与激酶、磷酸酶和其他酶相互作用，根据钙的波动调节其活性。这种在钙信号和各种细胞功能之间充当介导者的能力使得calmodulin（钙调蛋白）成为细胞信号复杂网络中的关键组成部分。 研究表明，calmodulin（钙调蛋白）功能的改变可能导致各种疾病。例如，calmodulin（钙调蛋白）基因的突变与心脏心律失常和其他心血管疾病有关。这些发现突显了calmodulin（钙调蛋白）在正常细胞功能和某些医学条件发病机制中的重要性。 除了在健康方面的作用外，calmodulin（钙调蛋白）还被研究用于生物技术和医学的潜在应用。通过了解calmodulin（钙调蛋白）如何与各种蛋白质相互作用，研究人员可以开发针对与钙信号失调相关疾病的靶向疗法。此外，calmodulin（钙调蛋白）可用于生物传感器，以检测生物样本中的钙水平，为研究和临床诊断提供有价值的信息。 总之，calmodulin（钙调蛋白）是一种重要的蛋白质，在钙信号和细胞调节中发挥着关键作用。它作为介导者的能力强调了它在维持细胞稳态中的重要性。对calmodulin（钙调蛋白）的研究不仅增强了我们对基本生物机制的理解，而且为推进医学科学和治疗干预提供了希望。随着研究不断揭示calmodulin（钙调蛋白）及其相互作用的复杂性，我们更接近于解锁治疗疾病和改善人类健康的新可能性。