cytochalasin

简明释义

英[ˌsaɪtəˈkæləsɪn]美[saɪtəˈkaɪləsɪn]

n. [生化] 细胞松弛素；松胞素

英英释义

单词用法

同义词

反义词

例句

1.Cytochalasin D experiments confirm that the movement of statoliths is actin-dependent and the actin filaments exert basipetal forces on statoliths in gravity field.

细胞松弛素D的实验证实平衡石的这种运动是和肌动蛋白丝相关，而且在重力场中作用于平衡石的向基力也是肌动蛋白丝产生的。

2.Cytochalasin D experiments confirm that the movement of statoliths is actin-dependent and the actin filaments exert basipetal forces on statoliths in gravity field.

细胞松弛素D的实验证实平衡石的这种运动是和肌动蛋白丝相关，而且在重力场中作用于平衡石的向基力也是肌动蛋白丝产生的。

3.Effects of cytochalasin B and thawing program on glass micropipette (GMP) vitrification of mouse mature oocytes were investigated.

探讨细胞松弛素b和解冻程序对玻璃微细管法(GMP)玻璃化冷冻小鼠卵母细胞的影响。

4.Enucleated cells are prepared by removing cell nuclei in the presence of the drug, cytochalasin b.

无核细胞是通过药物、细胞松驰素b把细胞核去掉制备的。

5.Researchers used cytochalasin to study its effects on cell division in their experiment.

研究人员使用细胞毒素来研究其对细胞分裂的影响。

6.The addition of cytochalasin inhibited the formation of actin filaments in the cultured cells.

添加细胞毒素抑制了培养细胞中肌动蛋白丝的形成。

7.In the presence of cytochalasin, the cells exhibited abnormal shapes and sizes.

在细胞毒素的存在下，细胞表现出异常的形状和大小。

8.The study demonstrated that cytochalasin can be used to manipulate cellular processes.

研究表明，细胞毒素可以用于操控细胞过程。

9.Scientists are investigating how cytochalasin affects cellular motility.

科学家们正在研究细胞毒素如何影响细胞运动性。

作文

In the realm of cell biology, many compounds play crucial roles in understanding cellular functions and processes. One such compound is cytochalasin, which is a class of mycotoxins produced by various species of fungi. These mycotoxins have garnered significant attention due to their ability to disrupt the cytoskeleton of cells, leading to profound effects on cellular behavior. The study of cytochalasin has not only provided insights into cellular mechanisms but has also paved the way for potential therapeutic applications. The primary function of cytochalasin is its interference with actin polymerization. Actin is a vital component of the cytoskeleton, which provides structural support to the cell and plays a pivotal role in various cellular processes, including division, motility, and intracellular transport. When cytochalasin is introduced into a cell, it binds to the barbed ends of actin filaments, preventing their elongation. This action leads to the disassembly of the cytoskeletal network, resulting in significant changes in cell shape and function. Researchers have utilized cytochalasin in various experimental settings to explore the dynamics of cell movement and division. For instance, studies involving fibroblast cells have shown that treatment with cytochalasin can inhibit cell migration, providing valuable insights into wound healing and cancer metastasis. By understanding how cytochalasin affects cell motility, scientists can better comprehend the underlying mechanisms of these critical biological processes. Moreover, cytochalasin has been instrumental in the field of immunology. It has been used to investigate the functioning of immune cells, particularly lymphocytes. By disrupting the cytoskeletal structure of these cells, researchers can study the impact on immune responses, including cell signaling and activation. This research is essential for developing new immunotherapies and understanding autoimmune diseases, where the immune system mistakenly targets the body’s own cells. Despite its usefulness in research, the application of cytochalasin is not without challenges. Its potent effects on the cytoskeleton can lead to unintended consequences in living organisms. Therefore, careful consideration is required when using cytochalasin in experimental designs. Researchers must balance the benefits of using this compound against the potential risks it poses to cellular integrity. In conclusion, cytochalasin stands out as a significant tool in cell biology, offering profound insights into the complexities of cellular function. Its ability to disrupt the cytoskeleton has made it a valuable asset in various fields of research, from cancer biology to immunology. As scientists continue to explore the multifaceted roles of cytochalasin, we can expect to uncover new therapeutic strategies and deepen our understanding of cellular dynamics. The ongoing study of this compound will undoubtedly contribute to advancements in medical science, ultimately improving our ability to treat diseases and understand life at the cellular level.

在细胞生物学领域，许多化合物在理解细胞功能和过程方面发挥着至关重要的作用。其中一种化合物是cytochalasin，它是一类由多种真菌产生的真菌毒素。这些真菌毒素因其能够干扰细胞的细胞骨架而受到广泛关注，从而对细胞行为产生深远影响。对cytochalasin的研究不仅提供了对细胞机制的深入理解，而且为潜在的治疗应用铺平了道路。 cytochalasin的主要功能是干扰肌动蛋白聚合。肌动蛋白是细胞骨架的重要组成部分，它为细胞提供结构支持，并在细胞分裂、运动和细胞内运输等各种细胞过程中发挥关键作用。当cytochalasin被引入细胞时，它会与肌动蛋白丝的光滑端结合，阻止其延长。这种作用导致细胞骨架网络的解体，从而导致细胞形状和功能发生显著变化。 研究人员在各种实验环境中利用cytochalasin探索细胞运动和分裂的动态。例如，涉及成纤维细胞的研究表明，用cytochalasin处理可以抑制细胞迁移，为伤口愈合和癌症转移提供了宝贵的见解。通过了解cytochalasin如何影响细胞运动，科学家们可以更好地理解这些关键生物过程的基本机制。 此外，cytochalasin在免疫学领域也发挥了重要作用。它被用于研究免疫细胞，特别是淋巴细胞的功能。通过破坏这些细胞的细胞骨架结构，研究人员可以研究对免疫反应的影响，包括细胞信号传导和激活。这项研究对开发新的免疫疗法和理解自身免疫疾病至关重要，在这些疾病中，免疫系统错误地攻击身体自身的细胞。 尽管在研究中具有实用性，但使用cytochalasin的应用并非没有挑战。它对细胞骨架的强大影响可能会导致对生物体的意外后果。因此，在实验设计中使用cytochalasin时需要谨慎考虑。研究人员必须在使用该化合物的好处与其对细胞完整性可能造成的风险之间取得平衡。 总之，cytochalasin作为细胞生物学中的重要工具，提供了对细胞功能复杂性的深刻见解。它对细胞骨架的干扰能力使其成为各个研究领域的宝贵资产，从癌症生物学到免疫学。随着科学家们继续探索cytochalasin的多方面作用，我们可以期待发现新的治疗策略，并加深对细胞动态的理解。这种化合物的持续研究无疑将促进医学科学的进步，最终改善我们治疗疾病和理解生命在细胞水平上的能力。