digitonin

简明释义

英[ˌdɪdʒɪˈtəʊnɪn]美[dɪdʒɪˈtoʊnɪn]

n. [药] 洋地黄皂苷

英英释义

单词用法

同义词

反义词

例句

1.Hepatocytes were isolated by the digitonin-collagenase perfusion technique.

肝细胞通过毛地黄皂苷-胶原酶灌流技术分离。

2.Hepatocytes were isolated by the digitonin-collagenase perfusion technique.

肝细胞通过毛地黄皂苷-胶原酶灌流技术分离。

3.The researchers used digitonin to permeabilize the cell membranes for their experiments.

研究人员使用digitonin来使细胞膜通透，以便进行实验。

4.In the study of membrane proteins, digitonin is often employed as a detergent.

在膜蛋白的研究中，digitonin常被用作洗涤剂。

5.To isolate mitochondria, the scientists added digitonin to the cell lysate.

为了分离线粒体，科学家们向细胞裂解液中添加了digitonin。

6.The effect of digitonin on cholesterol extraction was analyzed in the laboratory.

实验室分析了digitonin对胆固醇提取的影响。

7.Using digitonin, the team successfully extracted the membrane proteins from the cells.

利用digitonin，团队成功从细胞中提取了膜蛋白。

作文

Digitonin is a fascinating compound that has garnered attention in the field of biochemistry and pharmacology. It is a glycoside derived from the plant Digitalis, commonly known for its use in heart medication. The significance of digitonin lies in its ability to selectively permeabilize cell membranes, allowing researchers to study various cellular processes more effectively. This property makes digitonin an invaluable tool in laboratories worldwide. The mechanism of action of digitonin involves the interaction with cholesterol in cell membranes. By binding to cholesterol, digitonin forms complexes that disrupt the integrity of the lipid bilayer. This disruption leads to the formation of pores in the membrane, which facilitates the entry of substances that would typically be unable to penetrate the cell barrier. This unique characteristic has made digitonin a popular choice for scientists studying membrane dynamics and cellular transport mechanisms. One of the primary applications of digitonin is in the isolation of membrane proteins. Membrane proteins play crucial roles in various biological functions, including signal transduction, transport, and enzymatic activity. By using digitonin, researchers can selectively solubilize these proteins, enabling them to investigate their structure and function in detail. This process is essential for understanding how cells communicate and respond to their environment. Moreover, digitonin has been used in studies related to drug delivery systems. Its ability to enhance membrane permeability allows for the development of new therapeutic strategies that can improve the efficacy of drugs. For instance, when combined with certain pharmaceuticals, digitonin can facilitate the transport of these drugs into target cells, thereby increasing their therapeutic potential. In addition to its laboratory applications, digitonin has also been explored for its potential health benefits. Some studies suggest that it may exhibit antimicrobial properties, making it a candidate for developing new antibiotics. The ability of digitonin to disrupt bacterial membranes could lead to innovative treatments for bacterial infections that are resistant to conventional antibiotics. However, it is essential to approach the use of digitonin with caution. While it offers numerous advantages in research and potential therapeutic applications, its effects on human cells and tissues need thorough investigation. Safety assessments and regulatory approvals are critical before considering digitonin for clinical use. In conclusion, digitonin is a remarkable compound with significant implications in biochemistry and medicine. Its ability to permeabilize cell membranes opens up new avenues for research and therapeutic development. As scientists continue to explore the potential of digitonin, it is crucial to balance its benefits with safety considerations. The future of digitonin in both laboratory settings and clinical applications holds great promise, making it a compound worth watching in the coming years.

数字宁是一种引人注目的化合物，在生物化学和药理学领域引起了广泛关注。它是一种来自植物洋地黄的糖苷，通常用于心脏药物。数字宁的重要性在于其选择性渗透细胞膜的能力，使研究人员能够更有效地研究各种细胞过程。这一特性使得数字宁成为全球实验室中不可或缺的工具。 数字宁的作用机制涉及与细胞膜中的胆固醇相互作用。通过与胆固醇结合，数字宁形成复合物，破坏脂质双层的完整性。这种破坏导致膜中形成孔洞，从而促进通常无法穿透细胞屏障的物质进入细胞。这一独特特性使得数字宁成为科学家研究膜动态和细胞运输机制的热门选择。 数字宁的主要应用之一是在膜蛋白的分离中。膜蛋白在信号转导、运输和酶活性等各种生物功能中发挥着至关重要的作用。通过使用数字宁，研究人员可以选择性地溶解这些蛋白质，使他们能够详细调查其结构和功能。这个过程对于理解细胞如何与环境进行交流和响应至关重要。 此外，数字宁还被用于与药物输送系统相关的研究。其增强膜通透性的能力为开发新疗法提供了新的策略，可以提高药物的疗效。例如，当与某些药物结合时，数字宁可以促进这些药物进入靶细胞，从而增加其治疗潜力。 除了在实验室中的应用外，数字宁也因其潜在的健康益处而受到关注。一些研究表明，它可能具有抗微生物特性，使其成为开发新抗生素的候选者。数字宁破坏细菌膜的能力可能导致对抗耐药性细菌感染的新治疗方法的创新。 然而，在使用数字宁时必须谨慎。尽管它在研究和潜在治疗应用中提供了众多优势，但对其在人类细胞和组织上的影响需要彻底调查。在考虑将数字宁用于临床之前，安全评估和监管批准至关重要。 总之，数字宁是一种具有重大意义的化合物，在生物化学和医学领域具有重要的影响。其渗透细胞膜的能力为研究和治疗开发开辟了新的途径。随着科学家继续探索数字宁的潜力，平衡其益处与安全性考虑至关重要。数字宁在实验室环境和临床应用中的未来充满希望，使其成为未来几年值得关注的化合物。