digitoxin

简明释义

英[ˌdɪdʒɪˈtɒksɪn]美[ˌdɪdʒɪˈtɑːksɪn]

n. [药] 洋地黄毒苷

英英释义

单词用法

同义词

反义词

例句

1.The mechanism of vomiting by the dichroines and digitoxin is discussed.

本文又探讨了常山碱及洋地黄毒苷鸽催吐作用的机制问题。

2.The mechanism of vomiting by the dichroines and digitoxin is discussed.

本文又探讨了常山碱及洋地黄毒苷鸽催吐作用的机制问题。

3.The emetic mechanism by the digitoxin is discussed.

讨论了洋地黄毒物的催吐原理。

4.The doctor prescribed digitoxin for the patient's heart condition.

医生为患者的心脏病开了地高辛。

5.After taking digitoxin, the patient's symptoms improved significantly.

在服用地高辛后，患者的症状明显改善。

6.It is important to monitor the dosage of digitoxin to avoid toxicity.

监测地高辛的剂量以避免毒性是很重要的。

7.Some patients may experience side effects from digitoxin treatment.

一些患者可能会经历地高辛治疗的副作用。

8.Healthcare providers should educate patients about the use of digitoxin.

医疗提供者应教育患者关于地高辛的使用。

作文

In the world of medicine, there are many compounds that have been discovered and utilized for their therapeutic effects. One such compound is digitoxin, a cardiac glycoside that has been used for centuries to treat heart conditions. Derived from the leaves of the Digitalis plant, digitoxin works by increasing the force of heart contractions, making it particularly useful for patients suffering from heart failure or atrial fibrillation. This essay will explore the history, mechanism of action, therapeutic uses, and potential side effects of digitoxin, providing a comprehensive understanding of this important drug. Historically, the use of plants for medicinal purposes dates back thousands of years. The Digitalis plant, also known as foxglove, was first documented by herbalists in Europe. It wasn't until the 18th century that the active compounds within the plant, including digitoxin, were isolated and studied for their effects on the heart. The work of scientists like William Withering paved the way for the medical community to recognize the potential of digitoxin in treating various cardiac ailments. The mechanism of action of digitoxin is quite fascinating. It inhibits the sodium-potassium ATPase pump in cardiac cells, leading to an increase in intracellular sodium. This, in turn, causes an increase in calcium levels within the cell, enhancing the contractility of the heart muscle. As a result, digitoxin not only improves the efficiency of the heart but also helps regulate heart rhythm. This makes it an essential medication for individuals with congestive heart failure and other related conditions. Therapeutically, digitoxin is primarily prescribed to manage symptoms of heart failure and to control the heart rate in patients with atrial fibrillation. By improving the heart's pumping ability, it can alleviate symptoms such as shortness of breath and fatigue, allowing patients to lead more active lives. Additionally, digitoxin can be beneficial in certain cases of supraventricular tachycardia, where rapid heart rates need to be controlled. However, like any medication, digitoxin is not without its risks. The narrow therapeutic window of this drug means that the difference between an effective dose and a toxic dose is minimal. Patients taking digitoxin must be monitored closely for signs of toxicity, which can include nausea, vomiting, confusion, and even life-threatening arrhythmias. Factors such as kidney function and interactions with other medications can significantly affect the levels of digitoxin in the body, necessitating careful management by healthcare providers. In conclusion, digitoxin is a powerful cardiac glycoside with a rich history and a significant role in modern medicine. Its ability to enhance heart function makes it a valuable tool in managing heart failure and other cardiac conditions. However, due to its potential for toxicity, it is crucial for patients to be closely monitored while on this medication. Understanding the complexities of digitoxin not only highlights the importance of research in pharmacology but also emphasizes the need for responsible prescribing practices to ensure patient safety.

在医学世界中，有许多化合物被发现并用于其治疗效果。其中一种化合物是数字苷，一种心脏糖苷，已经被用于治疗心脏病数百年。它源自毛地黄植物的叶子，数字苷通过增强心脏收缩的力量来发挥作用，使其特别适用于患有心力衰竭或心房颤动的患者。本文将探讨数字苷的历史、作用机制、治疗用途和潜在副作用，从而全面了解这一重要药物。 从历史上看，植物用于药用的历史可以追溯到几千年前。毛地黄植物，也称为狐狸花，最早在欧洲的草药师文献中有所记载。直到18世纪，植物中的活性化合物，包括数字苷，才被分离并研究其对心脏的影响。威廉·威瑟林等科学家的工作为医学界认识到数字苷在治疗各种心脏疾病方面的潜力铺平了道路。 数字苷的作用机制非常吸引人。它抑制心脏细胞中的钠-钾ATP酶泵，导致细胞内钠离子增加。这反过来又导致细胞内钙离子水平的增加，从而增强心肌的收缩性。因此，数字苷不仅提高了心脏的效率，还帮助调节心率。这使其成为充血性心力衰竭和其他相关病症患者的重要药物。 在治疗上，数字苷主要用于管理心力衰竭的症状，以及控制心房颤动患者的心率。通过改善心脏的泵血能力，它可以缓解呼吸急促和疲劳等症状，使患者能够过上更积极的生活。此外，在某些室上性心动过速的情况下，数字苷也可能是有益的，因为快速的心率需要得到控制。 然而，像任何药物一样，数字苷也有其风险。这种药物的治疗窗口很窄，这意味着有效剂量与毒性剂量之间的差异很小。服用数字苷的患者必须密切监测毒性迹象，包括恶心、呕吐、混乱，甚至危及生命的心律失常。肾功能和与其他药物的相互作用等因素会显著影响体内数字苷的水平，因此需要医疗提供者的仔细管理。 总之，数字苷是一种强效的心脏糖苷，具有丰富的历史和在现代医学中的重要作用。它增强心脏功能的能力使其成为管理心力衰竭和其他心脏病症的宝贵工具。然而，由于其潜在的毒性，患者在服用这种药物时必须密切监测。理解数字苷的复杂性不仅突显了药理学研究的重要性，还强调了负责任的处方实践的必要性，以确保患者安全。