disubstituted

简明释义

英[/ˌdɪsʌbstəˈtjuːtɪd/]美[/ˌdɪsʌbstəˈtjuːtɪd/]

adj. 双取代的；二基取代的

英英释义

单词用法

同义词

反义词

例句

1.The synthesis of 2,5-disubstituted-1,3,4-thiadiazoles and their applications in corrosion resistance, anti-friction, liquid crystals, pesticides, pharmaceuticals, and chemical analysis were reviewed.

本文主要论述2，5-二取代-1，3，4-噻二唑类化合物的合成及其在抗腐蚀、抗磨擦、液晶、农药、医药、分析化学等方面的应用。

2.The synthesis of 2,5-disubstituted-1,3,4-thiadiazoles and their applications in corrosion resistance, anti-friction, liquid crystals, pesticides, pharmaceuticals, and chemical analysis were reviewed.

本文主要论述2，5-二取代-1，3，4-噻二唑类化合物的合成及其在抗腐蚀、抗磨擦、液晶、农药、医药、分析化学等方面的应用。

3.The relationship between structure and rotatory direction of 1, 2-disubstituted ferrocene and its derivatives is analyzed based on the helix theory proposed by the authors.

根据笔者所提出的螺旋理论，对1,2 -二取代二茂铁及其衍生物的结构与旋光方向间的关系进行了分析。

4.FOR a disubstituted complex, MA4B2, the planar arrangement gives three isomers, the familiar ortho, meta, and para arrangements of organic chemistry.

对于双取代络合物ma4b2，其平面排列有三个异构体，常见的为有机化学中的邻位、间位和对位排列。

5.The cis - or trans-2, 5-disubstituted tetrahydrofurans were provided by the hot decomposition and then hydrogenation of tricycle compounds produced.

所得的三环化合物经热分解和加氢反应，制备顺式和反式- 2,5 -二取代四氢呋喃。

6.The enantioselectivity for trans 1,2 disubstituted olefins is better than that for mono substituted olefins.

对反式- 1，2 -二取代烯烃的立体选择性优于单取代烯烃。

7.The key problem is to synthesize high stereoselectively trans- 2,5- disubstituted tetrahydrofurans.

高立体选择性合成反式-2，5-二取代四氢呋喃是期待解决的关键问题。

8.5- and 2,6-disubstituted benzazole analogues useful as protein kinase inhibitors.

用作蛋白激酶抑制剂的2，5和2，6双取代的氮茚类似物。

9.2,5- and 2,6-disubstituted benzazole analogues are used as protein kinase inhibitors.

2，5和2，6双取代氮茚类似物被用作蛋白激酶抑制剂。

10.The compound was found to be a disubstituted derivative, indicating it has two different substituents attached.

该化合物被发现是一个二取代的衍生物，表明它有两个不同的取代基附着。

11.In organic chemistry, disubstituted alkenes can exhibit unique properties compared to monosubstituted ones.

在有机化学中，二取代的烯烃与单取代的烯烃相比可能表现出独特的性质。

12.The reaction produced a disubstituted benzene ring, which is often more stable than monosubstituted variants.

反应生成了一个二取代的苯环，通常比单取代的变体更稳定。

13.Researchers synthesized a new disubstituted cyclohexane for their study on stereochemistry.

研究人员合成了一种新的二取代的环己烷，用于他们对立体化学的研究。

14.The disubstituted product showed improved solubility in polar solvents.

该二取代的产物在极性溶剂中的溶解度有所提高。

作文

In the world of organic chemistry, the term disubstituted refers to a molecule that has two substituent groups attached to its main structure. This concept is crucial for understanding the behavior and properties of various organic compounds. For example, when we consider aromatic compounds, a disubstituted benzene ring can exhibit different chemical reactivities depending on the nature and position of the substituents. The arrangement of these groups can lead to significant variations in the compound's physical and chemical properties, which is why chemists pay close attention to the concept of disubstituted structures. To illustrate, let’s take the example of disubstituted toluene. When we have two methyl groups on the benzene ring, the positions of these groups can be ortho, meta, or para. Each configuration will result in a different compound, each with distinct properties. The ortho isomer may have steric hindrance due to the proximity of the two methyl groups, while the para isomer might be more stable due to less steric strain. Understanding these nuances helps chemists predict how these molecules will react in various chemical reactions. Moreover, disubstituted compounds play a significant role in the synthesis of pharmaceuticals and other important chemicals. Many drugs are designed with specific substituents to enhance their efficacy and reduce side effects. By modifying the substituents on a core structure, chemists can create a wide array of compounds that target specific biological pathways. This is particularly evident in the development of cancer treatments, where disubstituted molecules can be tailored to interact with certain receptors or enzymes involved in tumor growth. Furthermore, the study of disubstituted compounds extends beyond just their chemical properties. It also encompasses the exploration of their biological activities. Researchers often investigate how different substituents influence the interaction of a compound with biological macromolecules like proteins and nucleic acids. These interactions can determine the therapeutic potential of a drug, making the understanding of disubstituted structures vital in medicinal chemistry. In conclusion, the term disubstituted is more than just a descriptor in organic chemistry; it represents a fundamental concept that influences the design, synthesis, and application of countless organic compounds. As we continue to explore the intricacies of molecular architecture, the importance of understanding disubstituted compounds cannot be overstated. They serve as a bridge between theoretical chemistry and practical applications, allowing scientists to innovate and improve upon existing technologies and treatments. Thus, mastering the concept of disubstituted structures is essential for anyone aspiring to make significant contributions to the field of chemistry, particularly in the areas of drug discovery and development.

在有机化学的世界中，术语disubstituted指的是一个分子在其主要结构上有两个取代基附着。这个概念对于理解各种有机化合物的行为和性质至关重要。例如，当我们考虑芳香化合物时，一个disubstituted苯环可以根据取代基的性质和位置表现出不同的化学反应性。这些基团的排列会导致化合物的物理和化学性质显著变化，这就是为什么化学家非常关注disubstituted结构的概念。 为了说明这一点，我们以disubstituted甲苯为例。当我们在苯环上有两个甲基时，这两个基团的位置可以是邻位、间位或对位。每种构型将导致不同的化合物，每种化合物具有独特的性质。邻位异构体可能由于两个甲基的接近而产生立体阻碍，而对位异构体由于较少的立体应变可能更稳定。理解这些细微差别有助于化学家预测这些分子在各种化学反应中的反应。 此外，disubstituted化合物在药物和其他重要化学品的合成中发挥着重要作用。许多药物的设计都带有特定的取代基，以增强其功效并减少副作用。通过修改核心结构上的取代基，化学家可以创造出一系列针对特定生物途径的化合物。这在癌症治疗的开发中尤为明显，其中disubstituted分子可以被定制以与某些受体或参与肿瘤生长的酶相互作用。 此外，对disubstituted化合物的研究不仅限于它们的化学性质。它还包括探索它们的生物活性。研究人员常常调查不同的取代基如何影响化合物与生物大分子如蛋白质和核酸的相互作用。这些相互作用可以决定药物的治疗潜力，因此理解disubstituted结构在药物化学中至关重要。 总之，术语disubstituted不仅仅是有机化学中的一个描述词；它代表了一个基本概念，影响着无数有机化合物的设计、合成和应用。随着我们继续探索分子结构的复杂性，理解disubstituted化合物的重要性不容小觑。它们作为理论化学与实际应用之间的桥梁，使科学家能够创新和改进现有技术和治疗。因此，掌握disubstituted结构的概念对于任何希望在化学领域，特别是在药物发现和开发方面做出重大贡献的人来说都是必不可少的。