disulphide

简明释义

英[daɪˈsʌlfaɪd]美[daɪˈsʌlfaɪd]

n. 二硫化物

英英释义

单词用法

同义词

反义词

例句

1.As a result, the recovery rate can get 73% in ice bath using carbon disulfide disulphide.

结论证明，在冰浴条件下，使用二硫化碳作为提取剂，其回收率可达73%。

2.The transition-metal sulphides are widely used as cathode in thermal batteries, especially iron disulphide and cobalt disulphide.

过渡族金属硫化物是一类很好的热电池正极材料。

3.Even in carbon disulphide in very dilute solution, the alcoholic spectrum shows some changes in the oh frequency due to solvent association.

即使在很稀的二硫化碳溶液中，醇类光谱还表现出由于与溶剂缔合而产生的OH频率的一些改变。

4.Results of a series of determinations of the content of disulphide bonds of a number of proteins by the above mentioned methods agreed satisfactorily with the values reported in the literature.

用上述二个方法对一些蛋白如胰岛素、木瓜蛋白酶、核糖核酸酶、胰疑乳蛋白酶、胰蛋白酶、人血清白蛋白等蛋白貭的硫硫键及巯基进行测定的结果与文献上报告符合。

5.This toxin consists of 33 amino acid residues with three disulphide bonds.

该毒素分子内含33个氨基酸残基，有三对二硫键。

6.The normal kind of bonds - disulphide bonds - can be broken by changes in heat and acidity, causing proteins to lose their 3d structure.

正常的链接是二硫键，可以被热度和酸度变化所破坏，导致蛋白质失去三维结构。

7.When carbon disulphide is producing by reacting carbon and sulphur, it brings about return sulphur in large quantities.

在木炭-硫磺法生产二硫化碳中，产生大量的回流硫磺。

8.The protein structure was stabilized by the formation of disulphide 二硫键 bonds between cysteine residues.

蛋白质结构通过半胱氨酸残基之间形成的disulphide 二硫键 键得以稳定。

9.In the laboratory, we used reducing agents to break disulphide 二硫键 bonds in the sample.

在实验室中，我们使用还原剂来破坏样品中的disulphide 二硫键 键。

10.Certain enzymes require disulphide 二硫键 bonds for their proper functioning.

某些酶需要disulphide 二硫键 键才能正常发挥作用。

11.The presence of disulphide 二硫键 bonds can influence the thermal stability of proteins.

存在的disulphide 二硫键 键会影响蛋白质的热稳定性。

12.In hair treatments, disulphide 二硫键 bonds are often broken and reformed to change texture.

在头发护理中，disulphide 二硫键 键通常被打断并重新形成以改变质地。

作文

The study of chemistry often leads us to fascinating compounds that play critical roles in various biological processes. One such compound is the disulphide (二硫化物), which is a chemical compound containing two sulfur atoms. Disulphides are particularly important in the field of biochemistry, where they contribute significantly to the structural stability of proteins. In this essay, I will explore the significance of disulphide bonds in protein structure and their implications in biological systems. Proteins are essential macromolecules that perform a myriad of functions in living organisms. They are composed of long chains of amino acids that fold into specific three-dimensional shapes. The stability of these shapes is crucial for the proteins to function correctly. One of the key factors that contribute to this stability is the formation of disulphide bonds between cysteine residues within the protein. These covalent bonds create cross-links that help maintain the protein's structure, especially under varying environmental conditions. The formation of disulphide bonds occurs during the process of protein folding. As a polypeptide chain folds, cysteine residues that are in proximity can undergo an oxidation reaction, leading to the creation of a disulphide bond. This reaction not only stabilizes the protein's conformation but also plays a role in the regulation of its activity. For instance, some enzymes require the presence of disulphide bonds to achieve their active form, thereby highlighting their functional importance. Moreover, disulphide bonds are not only limited to stabilizing individual proteins but also play a vital role in the assembly of multi-subunit protein complexes. In many cases, proteins must interact with other proteins to form functional units, and disulphide bonds can facilitate these interactions. For example, antibodies, which are crucial for the immune response, rely on disulphide bonds to maintain their Y-shaped structure, allowing them to effectively bind to antigens. The significance of disulphide bonds extends beyond structural integrity; they also have implications in disease. Misfolded proteins that fail to form the correct disulphide bonds can lead to various diseases, including neurodegenerative disorders like Alzheimer's and Parkinson's disease. In these conditions, the accumulation of misfolded proteins can disrupt cellular functions and lead to cell death. Therefore, understanding how disulphide bonds are formed and regulated is crucial for developing therapeutic strategies. In conclusion, disulphide bonds are fundamental to the structure and function of proteins. Their ability to stabilize protein conformation and facilitate protein interactions underscores their biological significance. As we continue to explore the intricate world of biochemistry, the role of disulphide bonds will undoubtedly remain a key area of research, particularly in understanding the molecular basis of diseases and developing novel treatments. By appreciating the importance of disulphide bonds, we can gain deeper insights into the complexities of life at the molecular level.

化学研究常常带领我们进入迷人的化合物世界，这些化合物在各种生物过程中起着关键作用。其中一种化合物是disulphide（二硫化物），它是一种含有两个硫原子的化学化合物。Disulphide在生物化学领域尤为重要，因为它们对蛋白质的结构稳定性贡献巨大。在这篇文章中，我将探讨disulphide键在蛋白质结构中的重要性及其在生物系统中的影响。 蛋白质是生命体内必不可少的高分子，它们在生物体内执行多种功能。蛋白质由长链氨基酸组成，这些氨基酸折叠成特定的三维形状。这些形状的稳定性对蛋白质的正常功能至关重要。形成disulphide键是影响这种稳定性的关键因素之一，disulphide键是在蛋白质内半胱氨酸残基之间形成的共价键。这些交联有助于维持蛋白质的结构，尤其是在不同环境条件下。 Disulphide键的形成发生在蛋白质折叠的过程中。当多肽链折叠时，靠近的半胱氨酸残基可以经历氧化反应，从而形成disulphide键。这一反应不仅稳定了蛋白质的构象，还在调节其活性方面发挥了作用。例如，一些酶需要存在disulphide键才能达到其活性形式，从而突显了其功能的重要性。 此外，disulphide键不仅限于稳定单个蛋白质，还在多亚基蛋白复合物的组装中发挥着重要作用。在许多情况下，蛋白质必须与其他蛋白质相互作用以形成功能单元，而disulphide键可以促进这些相互作用。例如，抗体在免疫反应中至关重要，依赖于disulphide键来维持其Y型结构，使其能够有效地结合抗原。 Disulphide键的重要性不仅体现在结构完整性上；它们在疾病中也有影响。未能形成正确的disulphide键的错误折叠蛋白可能导致各种疾病，包括阿尔茨海默病和帕金森病等神经退行性疾病。在这些情况下，错误折叠蛋白的积累会干扰细胞功能并导致细胞死亡。因此，理解disulphide键的形成和调节对于开发治疗策略至关重要。 总之，disulphide键是蛋白质结构和功能的基础。它们稳定蛋白质构象和促进蛋白质相互作用的能力凸显了它们的生物学重要性。随着我们继续探索生物化学的复杂世界，disulphide键的作用无疑将仍然是一个关键研究领域，特别是在理解疾病的分子基础和开发新疗法方面。通过欣赏disulphide键的重要性，我们可以更深入地洞察生命在分子水平上的复杂性。