dynein
简明释义
n. [生化] 动力蛋白
英英释义
A motor protein that moves along microtubules in cells, playing a key role in intracellular transport and the movement of cilia and flagella. | 一种在细胞内沿微管移动的马达蛋白,发挥着细胞内运输以及纤毛和鞭毛运动的关键作用。 |
单词用法
细胞质dynein | |
轴突dynein | |
dynein马达活性 | |
dynein介导的运输 | |
依赖dynein的运动 | |
dynein复合体 |
同义词
反义词
动力蛋白 | Kinesin transports cargo along microtubules toward the plus end. | 动力蛋白沿微管向正端运输货物。 | |
肌球蛋白 | Myosin interacts with actin filaments to facilitate muscle contraction. | 肌球蛋白与肌动蛋白相互作用以促进肌肉收缩。 |
例句
1.AIM: to detect the expression difference of axonemal dynein gene DNAI in bronchial tissues between the smoker and the non smoker, and to explore the effect of smoking on axonemal dynein gene.
目的:检测纤毛轴动力蛋白基因DNAI在吸烟者和非吸烟者支气管组织的表达差异,了解吸烟对纤毛轴动力蛋白基因的影响。
2.AIM: to detect the expression difference of axonemal dynein gene DNAI in bronchial tissues between the smoker and the non smoker, and to explore the effect of smoking on axonemal dynein gene.
目的:检测纤毛轴动力蛋白基因DNAI在吸烟者和非吸烟者支气管组织的表达差异,了解吸烟对纤毛轴动力蛋白基因的影响。
3.The expression of axonemal dynein gene DNAI in bronchial tissues of smoker significantly decreased, which may be one of the reasons for the decrease of cilium movement caused by smoking.
纤毛轴动力蛋白基因DNAI在吸烟者支气管组织中的表达明显降低,可能是吸烟造成纤毛运动功能下降的原因之一。
4.Recent studies have indicated the existence of dynein heavy chain and light chain in higher plants, but no data about dynein intermediate chain in higher plants have been reported.
近来的研究表明在高等植物细胞中存在细胞质力蛋白的重链和轻链,但力蛋白中间链在高等植物细胞中还未见报道。
5.The early axoneme of a basal body-axoneme complex consists nine doublets with only inner and outer dynein arms, no central microtubules.
一个早期基体—轴丝复合体的轴丝是由具有内、外动力蛋白臂的9个双微管组成,缺少中央微管。
6.Movement is based on the activities of tiny dynein side arms that extend from one of the microtubules of each doublet.
纤毛或鞭毛从 细胞表面的基体出生长,双微管的动力蛋白臂从一侧延伸到另一侧而引起运动。
7.Dynein Heavy Chain, Clone: 440.4, Mab anti.
动力蛋白重链,克隆:440.4,单克隆抗体抗。
8.The motor protein dynein 动力蛋白 is essential for transporting cellular components along microtubules.
动力蛋白dynein 动力蛋白 对于沿微管运输细胞成分至关重要。
9.In cilia and flagella, dynein 动力蛋白 generates the bending motion necessary for movement.
在纤毛和鞭毛中,dynein 动力蛋白 产生运动所需的弯曲运动。
10.Researchers are studying how dynein 动力蛋白 interacts with other proteins to facilitate intracellular transport.
研究人员正在研究dynein 动力蛋白 如何与其他蛋白质相互作用以促进细胞内运输。
11.Deficiencies in dynein 动力蛋白 function can lead to various neurological disorders.
缺乏dynein 动力蛋白 功能可能导致各种神经系统疾病。
12.The study of dynein 动力蛋白 has implications for understanding cancer cell metastasis.
对dynein 动力蛋白 的研究对理解癌细胞转移具有重要意义。
作文
In the intricate world of cellular biology, the role of motor proteins is paramount for maintaining the functionality and structure of cells. One such motor protein is dynein, which is essential for various cellular processes, particularly in the transport of cellular components. Dynein is a complex protein that moves along microtubules, which are part of the cytoskeleton, the structural framework of the cell. This movement is critical for the proper distribution of organelles, vesicles, and other cargo within the cell. The function of dynein is particularly highlighted during the process of mitosis, where it plays a vital role in the separation of chromosomes. During cell division, dynein helps to pull the chromosomes apart, ensuring that each daughter cell receives the correct number of chromosomes. This function is crucial because any errors in chromosome segregation can lead to conditions such as cancer or genetic disorders. Moreover, dynein is also involved in the transport of signaling molecules and other important proteins. For instance, it transports neurotrophic factors along axons in neurons, which is essential for the survival and growth of nerve cells. The proper functioning of dynein is therefore vital for neuronal health and communication, highlighting its importance in the nervous system. Interestingly, dynein operates in conjunction with another type of motor protein called kinesin. While dynein generally moves cargo toward the cell's interior (retrograde transport), kinesin typically transports materials toward the cell's periphery (anterograde transport). This coordinated movement ensures that cellular components are efficiently distributed throughout the cell, maintaining cellular homeostasis. Research into dynein has expanded significantly in recent years, revealing its complex structure and regulatory mechanisms. It is composed of multiple subunits, which assemble into a functional motor complex. Mutations in dynein or its associated proteins can lead to severe diseases, including neurodegenerative disorders and ciliopathies, which are diseases caused by defects in cilia function. Understanding dynein and its pathways is thus an active area of research, with scientists seeking to unravel the mysteries of its operation and its implications for human health. In conclusion, dynein is not just a simple motor protein; it is a critical player in the orchestration of cellular dynamics. Its ability to transport essential materials and facilitate cell division underscores its significance in biology. As we continue to explore the functions and mechanisms of dynein, we gain deeper insights into the complexities of life at the cellular level, paving the way for potential therapeutic interventions in diseases linked to its dysfunction.
在细胞生物学的复杂世界中,马达蛋白的角色对于维持细胞的功能和结构至关重要。其中一种马达蛋白是dynein,它对各种细胞过程至关重要,特别是在细胞成分的运输中。Dynein是一种复杂的蛋白质,沿着微管移动,微管是细胞骨架的一部分,构成了细胞的结构框架。这种运动对于细胞内细胞器、囊泡和其他货物的适当分配至关重要。 Dynein的功能在有丝分裂过程中尤为突出,它在染色体分离中发挥着重要作用。在细胞分裂期间,dynein帮助拉动染色体,确保每个子细胞获得正确数量的染色体。这一功能至关重要,因为染色体分配中的任何错误都可能导致癌症或遗传疾病等情况。 此外,dynein还参与信号分子和其他重要蛋白质的运输。例如,它沿着神经元的轴突运输神经营养因子,这对神经细胞的生存和生长至关重要。因此,dynein的正常功能对神经健康和通信至关重要,突显了它在神经系统中的重要性。 有趣的是,dynein与另一种类型的马达蛋白称为动力蛋白(kinesin)协同工作。虽然dynein通常将货物运输到细胞内部(逆向运输),但动力蛋白通常将材料运输到细胞的边缘(正向运输)。这种协调运动确保了细胞成分在整个细胞内的高效分布,维持细胞的动态平衡。 近年来,对dynein的研究显著增加,揭示了其复杂的结构和调控机制。它由多个亚单位组成,这些亚单位组装成一个功能性马达复合物。dynein或其相关蛋白的突变可能导致严重的疾病,包括神经退行性疾病和纤毛病,这些疾病是由纤毛功能缺陷引起的。因此,理解dynein及其通路是一个活跃的研究领域,科学家们正在努力揭开其操作的奥秘及其对人类健康的影响。 总之,dynein不仅仅是一种简单的马达蛋白;它是细胞动态协调中的关键参与者。它运输必需材料和促进细胞分裂的能力突显了其在生物学中的重要性。随着我们继续探索dynein的功能和机制,我们对细胞层面生命的复杂性有了更深刻的见解,为与其功能障碍相关疾病的潜在治疗干预铺平了道路。
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