enantiomer

简明释义

英[enˈæntɪəmə(r)]美[ɪˈnæntiəmər]

n. [有化] 对映体；[数][有化] 对映异构体

英英释义

单词用法

同义词

反义词

例句

1.Enantiomer separation is one of the most important research fields of chiral technology.

手性拆分是手性技术的重要研究方向。

2.The enantiomer of some chiral drugs has different pharmacology activity and different applying.

手性药物对映体具有不同的药理活性和不同的用途。

3.It was found that resolution of enantiomer of neutral compound was enhanced by adding certain amount of methanol.

同时发现，一定含量的甲醇可以提高中性化合物对映体分离度。

4.In response to the best conditions, the reaction rate achieved 98.5% and the enantiomer excess value achieved 100%.

在最佳反应条件下反应的产率达到98.5%，产物的对映体过量值达到100%。

5.From 1-phenyl-2-propylamine, selegiline hydrochloride, an anti-Parksins drug, was synthesized via N-methylation, enantiomer separation, N-alkylation and salt formation with an overall yield of 42.2%.

以1- 苯基- 2-丙胺为原料，经N- 甲基化、拆分、N-炔基化、成盐共4步反应合成盐酸司来吉兰，总收率为42。

6.Objective: to establish an HPLC method for the resolution of metoprolol enantiomer using chiral mobile phase additives.

目的：建立hplc手性流动相添加剂法拆分美托洛尔对映体的方法。

7.The configuration inversion can offer the desired enantiomer in high efficiency, but with certain limitation in application.

构型反转能够直接得到所需要的对映体，效率高，但其应用局限性较大；

8.The enantiomer that rotates the plane to the right is referred to as the dextrorotatory.

使平面向右旋转的对映体，称为右旋对映体。

9.Chemical synthesis course is simple which can be industrialized, the product is DL-enantiomer, it is difficult to separate and get rid of D-Theanine.

而化学合成法制备茶氨酸，操作相对简单，易于工业化生产，但产品多为D -、L -的混旋体，D -茶氨酸的分离与去除具有较高的技术难度。

10.The two compounds are mirror images of each other, making one an enantiomer (对映体) of the other.

这两种化合物是彼此的镜像，使得其中一种成为另一种的enantiomer（对映体）。

11.In pharmaceuticals, the efficacy of a drug can vary significantly between its enantiomer (对映体) and its counterpart.

在药物中，药物的疗效在其enantiomer（对映体）和其对应物之间可能有显著差异。

12.Chemists often use chiral catalysts to selectively produce one enantiomer (对映体) over another.

化学家通常使用手性催化剂来选择性地生产一种enantiomer（对映体）而不是另一种。

13.The enantiomer (对映体) of this molecule is known to have a completely different smell.

这个分子的enantiomer（对映体）已知具有完全不同的气味。

14.A racemic mixture contains equal amounts of both enantiomers (对映体) and is often less effective than a pure form.

一个外消旋混合物包含两种enantiomers（对映体）的等量，通常效果不如纯形式。

作文

In the fascinating world of chemistry, the concept of chirality plays a pivotal role in understanding the behavior of molecules. One of the key terms associated with chirality is enantiomer, which refers to one of two stereoisomers that are mirror images of each other but cannot be superimposed. This unique property makes enantiomers crucial in various fields, especially in pharmaceuticals, where the effectiveness and safety of drugs can depend on their chirality. For instance, consider the drug thalidomide, which was used in the late 1950s as a sedative. It exists as two enantiomers: one that was effective in alleviating morning sickness in pregnant women, and another that caused severe birth defects. This tragic outcome highlighted the importance of understanding enantiomers in drug design and development. The study of enantiomers is not limited to pharmaceuticals; it extends to the fields of agriculture and food science as well. Many natural products, such as amino acids and sugars, exist as enantiomers, and their biological activities can differ significantly. For example, while one enantiomer of an amino acid might be utilized by the body for protein synthesis, its mirror image could be ineffective or even harmful. This specificity underscores the need for chemists to carefully consider the enantiomers they are working with when synthesizing new compounds. Moreover, the concept of enantiomers is also essential in the field of sensory perception. The way we perceive taste and smell can be influenced by the chirality of molecules. For instance, the enantiomers of certain odorants can produce distinctly different smells. This phenomenon is evident in the case of carvone, a compound found in spearmint and caraway seeds. One enantiomer of carvone has a minty aroma, while the other smells like caraway. Such differences can have significant implications in flavoring and fragrance industries, where the desired sensory attributes are paramount. To better understand enantiomers, it is important to explore the methods used to differentiate them. One common technique is optical activity, which involves measuring the rotation of plane-polarized light as it passes through a solution containing enantiomers. Each enantiomer will rotate the light in opposite directions, allowing chemists to identify and quantify the specific enantiomers present in a mixture. This analytical method is vital for ensuring the purity and efficacy of pharmaceutical products. In conclusion, the term enantiomer encapsulates a fundamental concept in chemistry that has far-reaching implications across various scientific disciplines. From drug development to agriculture and sensory perception, understanding enantiomers is crucial for harnessing their unique properties and ensuring safety and effectiveness in practical applications. As research continues to advance, the significance of enantiomers will only grow, paving the way for innovative discoveries and improvements in numerous fields. Therefore, a solid grasp of enantiomers is essential for anyone aspiring to make meaningful contributions to the sciences.

在化学的迷人世界中，手性概念在理解分子行为方面起着关键作用。与手性相关的一个关键术语是对映体，指的是两个立体异构体之一，它们是彼此的镜像，但不能重叠。这种独特的特性使得对映体在各个领域中至关重要，尤其是在制药领域，药物的有效性和安全性可能依赖于其手性。例如，考虑药物沙利度胺，它在20世纪50年代末作为镇静剂使用。它存在两种对映体：一种有效缓解孕妇的晨吐，另一种则导致严重的出生缺陷。这一悲惨的结果突显了在药物设计和开发中理解对映体的重要性。 对对映体的研究不仅限于制药；它还扩展到农业和食品科学等领域。许多天然产物，如氨基酸和糖，存在为对映体，它们的生物活性可能有显著差异。例如，虽然一种对映体的氨基酸可能被身体用于蛋白质合成，但其镜像可能无效甚至有害。这种特异性强调了化学家在合成新化合物时仔细考虑他们所处理的对映体的必要性。 此外，对映体的概念在感官感知领域也至关重要。我们感知味道和气味的方式可能受到分子手性的影响。例如，某些气味分子的对映体可以产生截然不同的气味。这种现象在薄荷醇的案例中尤为明显，薄荷醇是一种存在于薄荷和香车前子的化合物。薄荷醇的一种对映体具有薄荷香，而另一种则闻起来像香车前子。这种差异在调味品和香水行业中可能具有重大意义，因为所需的感官特性至关重要。 为了更好地理解对映体，重要的是探索区分它们的方法。一种常见的技术是光学活性，这涉及测量平面偏振光通过含有对映体的溶液时的旋转。每种对映体将以相反的方向旋转光，从而允许化学家识别和量化混合物中存在的特定对映体。这种分析方法对于确保药物产品的纯度和有效性至关重要。 总之，术语对映体概括了化学中的一个基本概念，该概念在各个科学学科中具有深远的影响。从药物开发到农业和感官感知，理解对映体对于利用其独特属性并确保实际应用的安全性和有效性至关重要。随着研究不断推进，对映体的重要性只会增加，为各个领域的创新发现和改进铺平道路。因此，扎实掌握对映体对于任何希望对科学做出有意义贡献的人来说都是必不可少的。