epitope

简明释义

英[ˈepɪˌtəʊp]美[ˈepɪˌtoʊp]

n. [免疫] 表位；抗原决定部位；抗原决定基

英英释义

单词用法

同义词

反义词

例句

1.Objective to explore the relationship between the immune response induced by 6b11 anti-idiotypic antibody and its epitope peptides.

目的探讨卵巢癌抗独特型抗体6b11表位多肽与诱导免疫应答之间的关系。

2.The method based on expressed peptide for mapping epitope on viral prot…

实验表明，用基因工程表达的多肽筛选抗原表位的方法是可行的。

3.Objective to construct an eukaryotic expression vector of compound multi-epitope gene of HCV and express the gene in COS7 cells.

目的建立丙型肝炎病毒(HCV)复合多表位基因的真核表达载体，并在COS7细胞中瞬时表达。

4.However, in the HLA A2 - individual, the epitope had neither variation nor amber mutation in 5 years after infection.

在无HLAA2表型的感染者中，其感染后5年病毒抗原表位肽段既无共有序列的变异，也无琥珀突变。

5.The results of superposable test suggest that 5A5, 5C12 and 6F5 were against different antigen epitope.

叠加实验表明，5A5、5C12和6F5三株单抗抗原识别位点均不相同。

6.The result demonstrated that Rhesus monkey immunized by multi-epitope PCX could elicit high-level immune responses.

结果表明，免疫多表位的PCX蛋白可以诱导机体产生高水平的免疫应答。

7.The vaccine was designed to target a specific epitope (表位) on the virus's surface.

该疫苗旨在针对病毒表面特定的epitope (表位)。

8.Researchers are studying how different epitopes (表位) can trigger immune responses.

研究人员正在研究不同的epitopes (表位) 如何引发免疫反应。

9.Identifying the epitope (表位) is crucial for developing effective antibodies.

识别epitope (表位) 对于开发有效抗体至关重要。

10.The epitope (表位) mapping technique helps scientists understand protein interactions.

epitope (表位) 映射技术帮助科学家理解蛋白质相互作用。

11.Some vaccines use synthetic epitopes (表位) to elicit a stronger immune response.

一些疫苗使用合成的epitopes (表位) 来引发更强的免疫反应。

作文

The immune system is a complex network that protects the body from harmful pathogens. One of the key components of this system is the recognition of foreign substances, which is primarily mediated by antibodies. A crucial aspect of this recognition process involves a specific part of the pathogen known as an epitope (表位). An epitope is defined as the precise region on the surface of an antigen that is recognized by the immune system, particularly by antibodies, T cells, or B cells. Understanding epitopes is vital for vaccine development and immunotherapy, as they play a significant role in determining how effectively the immune system can respond to infections and diseases. To grasp the importance of epitopes, we first need to understand antigens. Antigens are molecules or molecular structures that are recognized by the immune system as foreign. They can be proteins, polysaccharides, or even nucleic acids. When a pathogen enters the body, the immune system identifies it by detecting these antigens. However, not all parts of an antigen are equally effective in eliciting an immune response. This is where epitopes come into play. There are two main types of epitopes: linear and conformational. Linear epitopes consist of a continuous sequence of amino acids within a protein, while conformational epitopes are formed by the three-dimensional shape of the protein, which brings together amino acids that are not sequentially adjacent. The distinction between these types is crucial because it influences how antibodies bind to antigens. For instance, many vaccines aim to present epitopes in a way that mimics the natural structure of the pathogen, thereby enhancing the immune response. The study of epitopes has significant implications in the field of medicine. In vaccine development, identifying the most effective epitopes allows researchers to create targeted vaccines that can elicit strong and lasting immune responses. For example, the success of mRNA vaccines against COVID-19 relies heavily on the incorporation of specific viral epitopes that trigger an immune response without causing disease. In addition, understanding epitopes is essential for designing therapies for autoimmune diseases, where the immune system mistakenly targets the body’s own tissues. By identifying self-epitopes, researchers can develop treatments that modulate the immune response, potentially leading to better management of these conditions. Moreover, the concept of epitopes extends beyond infectious diseases. In cancer therapy, tumor-associated epitopes can be targeted to stimulate the immune system to recognize and destroy cancer cells. This approach, known as cancer immunotherapy, has shown promising results in various clinical trials, highlighting the versatility and significance of epitopes in modern medicine. In conclusion, epitopes (表位) are fundamental to the immune response and play a pivotal role in the development of vaccines and therapeutic strategies. As our understanding of these critical components of the immune system continues to evolve, we can expect advancements in disease prevention and treatment that leverage the power of epitopes. The ongoing research in this area not only enhances our knowledge of immunology but also opens new avenues for innovative medical solutions.