esterases

简明释义

英[ˈestəˌreɪs]美[ˈestəˌreɪzɪz]

n. [生化]酯酶（esterase 的复数形式）

英英释义

单词用法

同义词

反义词

例句

1.Extensive study of some pectinase such as protopectinases, polygalacturonases, lyases and pectin esterases has been done up to the present.

在果胶酶中，原果胶酶、聚半乳糖醛酸酶、裂解酶和果胶酯酶得到了广泛深入的研究。

2.Extensive study of some pectinase such as protopectinases, polygalacturonases, lyases and pectin esterases has been done up to the present.

在果胶酶中，原果胶酶、聚半乳糖醛酸酶、裂解酶和果胶酯酶得到了广泛深入的研究。

3.The present invention relates to the use of insect esterases or lipases, or mutants thereof, as catalysts in biotransformation processes.

本发明涉及昆虫酯酶或脂肪酶，或其突变体在生物转化过程中作为催化剂的应用。

4.Spectrum of esterases in skin proved to be associated with the group differences of wool production characters.

谱酯酶皮肤被证明与该组织有关分歧的羊毛生产字符。

5.These compounds include an ester bond making them sensitive to deactivation by esterases.

这些化合物包括使其对由酯酶引起的失活敏感的酯键。

6.Lipases thus comprises a subclass of the esterases.

因此，脂肪酶的酯酶包括一个子类。

7.The study focused on the role of esterases in drug metabolism.

这项研究集中在酯酶在药物代谢中的作用。

8.Certain esterases can break down toxic compounds in the environment.

某些酯酶可以分解环境中的有毒化合物。

9.Researchers are investigating how esterases affect lipid metabolism.

研究人员正在调查酯酶如何影响脂质代谢。

10.Inhibition of esterases may lead to increased drug efficacy.

抑制酯酶可能会导致药物效力增加。

11.Genetic variations in esterases can influence individual responses to medications.

在酯酶中的遗传变异可以影响个体对药物的反应。

作文

Esterases are a group of enzymes that play a crucial role in the metabolism of esters, which are organic compounds formed from the reaction between an alcohol and an acid. These enzymes are found in various organisms, including humans, where they contribute to the breakdown of lipids and other ester-containing compounds. Understanding the function of esterases (酯酶) is essential for several reasons, particularly in the fields of biochemistry and pharmacology. Firstly, esterases (酯酶) are involved in detoxifying certain drugs and chemicals within the body. For instance, when a pharmaceutical drug is administered, it often exists in an ester form to enhance its bioavailability. Once inside the body, esterases (酯酶) can hydrolyze these esters, converting them into their active forms or facilitating their excretion. This process is vital for maintaining the appropriate therapeutic levels of drugs and minimizing potential toxicity. Moreover, esterases (酯酶) play a significant role in lipid metabolism. They help in the digestion and absorption of dietary fats by breaking down triglycerides into free fatty acids and glycerol. This action not only aids in nutrient absorption but also regulates energy homeostasis within the body. The activity of esterases (酯酶) can be influenced by various factors, including diet, hormonal changes, and the presence of certain diseases. In addition to their metabolic functions, esterases (酯酶) have been implicated in various physiological processes. For example, they are involved in the modulation of neurotransmitter signaling. Some esterases (酯酶) can hydrolyze neurotransmitters like acetylcholine, thereby regulating synaptic transmission and influencing muscle contraction and cognitive functions. This highlights the importance of esterases (酯酶) beyond mere metabolism, as they also participate in critical signaling pathways in the body. Furthermore, research on esterases (酯酶) has significant implications for drug development and disease treatment. Scientists are exploring the potential of inhibiting specific esterases (酯酶) to enhance the efficacy of certain drugs or to develop new therapeutic agents. For example, inhibitors of acetylcholinesterase, a type of esterase (酯酶), are used in the treatment of Alzheimer’s disease to increase levels of acetylcholine in the brain, thereby improving cognitive function. On the other hand, the overactivity of certain esterases (酯酶) can lead to adverse effects. For instance, excessive breakdown of esters can result in insufficient availability of essential fatty acids, which are crucial for various bodily functions, including cellular structure and hormone production. Therefore, a balanced regulation of esterases (酯酶) is vital for maintaining health. In conclusion, esterases (酯酶) are essential enzymes that facilitate the metabolism of esters and play diverse roles in drug metabolism, lipid digestion, and neurotransmitter regulation. Their significance extends beyond basic metabolic functions, influencing various physiological processes and offering potential avenues for therapeutic interventions. As research continues to uncover the complexities of esterases (酯酶) and their functions, we gain deeper insights into their importance in health and disease management.

酯酶是一类在酯的代谢中起重要作用的酶，这些酶是由醇和酸反应形成的有机化合物。这些酶存在于各种生物体中，包括人类，在其中它们对脂质和其他含酯化合物的分解作出贡献。理解酯酶（esterases）的功能对于生物化学和药理学等多个领域至关重要。 首先，酯酶（esterases）参与了体内某些药物和化学物质的解毒。例如，当药物被施用时，它通常以酯的形式存在，以增强其生物利用度。一旦进入体内，酯酶（esterases）可以水解这些酯，将其转化为活性形式或促进其排泄。这个过程对于维持药物的适当治疗水平和最小化潜在毒性至关重要。 此外，酯酶（esterases）在脂质代谢中也发挥着重要作用。它们通过将甘油三酯分解为游离脂肪酸和甘油，帮助消化和吸收膳食脂肪。这个作用不仅有助于营养物质的吸收，还调节了体内的能量稳态。酯酶（esterases）的活性可能受到多种因素的影响，包括饮食、激素变化和某些疾病的存在。 除了代谢功能外，酯酶（esterases）还与各种生理过程有关。例如，它们参与神经递质信号的调节。一些酯酶（esterases）可以水解神经递质如乙酰胆碱，从而调节突触传递并影响肌肉收缩和认知功能。这突显了酯酶（esterases）在代谢之外的重要性，因为它们也参与了体内关键的信号通路。 此外，关于酯酶（esterases）的研究对药物开发和疾病治疗具有重要意义。科学家们正在探索抑制特定酯酶（esterases）以增强某些药物的有效性或开发新的治疗剂的潜力。例如，乙酰胆碱酯酶抑制剂，一种类型的酯酶（esterases），用于治疗阿尔茨海默病，以提高大脑中的乙酰胆碱水平，从而改善认知功能。 另一方面，某些酯酶（esterases）的过度活跃可能导致不良影响。例如，过度分解酯可能导致必需脂肪酸的可用性不足，而这些脂肪酸对各种身体功能至关重要，包括细胞结构和激素生产。因此，适度调节酯酶（esterases）对于维持健康至关重要。 总之，酯酶（esterases）是促进酯代谢的基本酶，发挥着药物代谢、脂质消化和神经递质调节等多种角色。它们的重要性超越了基本的代谢功能，影响着各种生理过程，并为治疗干预提供了潜在途径。随着研究不断揭示酯酶（esterases）及其功能的复杂性，我们对它们在健康和疾病管理中的重要性有了更深入的了解。