excipients

简明释义

英[ɪkˈsɪpɪənts]美[ɪkˈsɪpɪrnts]

n. [药]赋形剂（excipient 的复数）

英英释义

单词用法

同义词

反义词

例句

1.The company mainly produces new type of pharmaceutical excipients, food additives.

公司主要生产新型药用辅料、食品添加剂。

2.Excipients quality issues: quality, not up accessories, or not done in accordance with recognized.

辅料质量问题：辅料质量不过关，或者没有按照确认的来做。

3.Objective: to introduce the application of excipients for oral colon-targeting drugs, and to provide the reference for future research.

目的：介绍辅料在口服结肠靶向制剂中的应用，为更深入的研究提供参考。

4.Used in the food, pharmaceutical excipients, such as textile warp sizing.

应用于食品、医药辅料、纺织经纱上浆等。

5.The preparations of drug-loading particles and excipients particles and selection of excipients are reviewed.

综述了其中载药微粒和辅料颗粒的制备方法、辅料的选择等研究概况。

6.Objective To study the compatability between atenolol and different excipients.

目的考察阿替洛尔与片剂辅料的相容性。

7.Thermogravimetry was used to study the non-isothermal decomposition kinetics and the difference of stability between cefalexin and its excipients.

采用热重法研究头孢氨苄热分解非等温动力学和头孢氨苄与其制剂的稳定性差异。

8.Can be used as food sweeteners or excipients used in the various food production and processing in the field.

可作为食品的甜味剂或是赋形剂应用于各个食品的生产加工领域中。

9.The formulation of the drug includes various excipients that help stabilize the active ingredients.

该药物的配方包括多种辅料，有助于稳定活性成分。

10.Pharmaceutical companies often test different excipients to enhance drug absorption.

制药公司经常测试不同的辅料以提高药物吸收率。

11.Some excipients are used to improve the taste of oral medications.

一些辅料用于改善口服药物的味道。

12.In the production of tablets, excipients play a crucial role in ensuring uniformity.

在片剂的生产中，辅料在确保均匀性方面发挥着至关重要的作用。

13.The safety of excipients is carefully evaluated during the drug development process.

在药物开发过程中，辅料的安全性会被仔细评估。

作文

In the pharmaceutical industry, the term excipients refers to substances that are included in a drug formulation but do not have any therapeutic effect. These materials play a crucial role in the production and effectiveness of medications. For instance, excipients can enhance the stability of the active ingredients, improve the absorption of the drug in the body, or aid in the manufacturing process by allowing for easier handling and processing of the medication. One of the most common types of excipients is the binder, which helps hold the ingredients of a tablet together. Without binders, tablets would crumble easily, making them difficult to administer. Another important category of excipients includes fillers, which add bulk to the medication and ensure that the dosage is appropriate. Fillers are particularly important for low-dose medications, where the active ingredient might be present in very small quantities. Additionally, excipients can also serve as preservatives, ensuring that the medication remains effective throughout its shelf life. This is particularly important for liquid formulations, which may be more susceptible to microbial growth. By incorporating excipients that have preservative properties, manufacturers can prolong the stability and safety of their products. Moreover, the choice of excipients is critical in determining the overall quality of a pharmaceutical product. The compatibility of the excipients with the active pharmaceutical ingredients (APIs) must be thoroughly evaluated to avoid any adverse reactions that could compromise the drug's efficacy. For example, certain excipients might interact negatively with specific APIs, leading to degradation of the drug or reduced bioavailability. Therefore, extensive testing is conducted during the formulation development phase to ensure that all components work harmoniously together. The importance of excipients extends beyond just drug formulation; they also play a significant role in patient compliance. Medications that are easier to swallow, taste better, or are more palatable often contain carefully chosen excipients that enhance the user experience. For example, flavoring agents and sweeteners can be added to pediatric formulations to make them more appealing to children. Similarly, coating agents can be used to mask unpleasant tastes or odors, making it easier for patients to adhere to their prescribed regimens. In conclusion, while excipients may not have any direct therapeutic effects, their importance in the pharmaceutical industry cannot be overstated. They contribute to the stability, efficacy, and overall quality of medications, ensuring that patients receive safe and effective treatments. As research continues to advance, the development of new and improved excipients will undoubtedly enhance the field of drug formulation, leading to better health outcomes for patients worldwide.

在制药行业中，术语excipients指的是那些包含在药物配方中但没有治疗效果的物质。这些材料在药物的生产和有效性中起着至关重要的作用。例如，excipients可以增强活性成分的稳定性，提高药物在体内的吸收，或者通过便于药物的处理和加工来帮助制造过程。 最常见的excipients类型之一是粘合剂，它有助于将片剂的成分结合在一起。如果没有粘合剂，片剂将容易崩溃，使其难以服用。另一个重要的excipients类别包括填充剂，它们为药物增加体积，并确保剂量适当。填充剂对于低剂量药物尤其重要，因为活性成分可能仅以非常小的数量存在。 此外，excipients还可以作为防腐剂，确保药物在整个保质期内保持有效。这对于液体配方尤为重要，因为它们可能更容易受到微生物生长的影响。通过加入具有防腐特性的excipients，制造商可以延长其产品的稳定性和安全性。 此外，excipients的选择对制药产品的整体质量至关重要。必须彻底评估excipients与活性药物成分（API）的兼容性，以避免任何可能导致药物疗效下降的不良反应。例如，某些excipients可能与特定的API产生负面相互作用，导致药物降解或生物利用度降低。因此，在配方开发阶段会进行广泛的测试，以确保所有成分能够和谐地协同工作。 excipients的重要性不仅限于药物配方；它们在患者依从性方面也发挥着重要作用。那些更易吞咽、味道更好或更可口的药物通常含有精心挑选的excipients，以增强用户体验。例如，儿童配方中可以添加调味剂和甜味剂，以使其对儿童更具吸引力。同样，涂层剂可以用于掩盖不愉快的味道或气味，使患者更容易遵循处方方案。 总之，虽然excipients可能没有直接的治疗效果，但它们在制药行业中的重要性不可低估。它们有助于药物的稳定性、有效性和整体质量，确保患者获得安全有效的治疗。随着研究的不断进展，新型和改进的excipients的发展无疑将增强药物配方领域，为全球患者带来更好的健康结果。