excipient

简明释义

英[ekˈsɪpiənt]美[ɪkˈsɪpɪənt]

n. [药] 赋形剂

英英释义

单词用法

同义词

反义词

例句

1.If an excipient manufacturer states that class 2 solvents are present in their excipient, but below the option 1 limit, does the drug product manufacturer have to test for these solvents?

如果辅料生产商声明其辅料中存在2类溶剂，但低于选项1限度，制剂生产商是否必须测试其溶剂？

2.The method was simple, stable and undisturbed with excipient.

该法简便，样液稳定，赋形剂对测定无干扰。

3.Results and conclusions PEG is a very useful excipient in different kinds of preparations.

结果与结论聚乙二醇是一种重要药物辅料，在各种剂型中应用广泛。

4.Methods: According to their effects on the hardening depth and surface characteristic of the set materials, the water-hardening components, excipient vehicles, coagulation accelerators were selected.

方法：通过测定材料在水中的凝固速度及凝固后材料表面性状，对水硬性材料成份的种类、赋形剂的种类及凝固促进剂的种类进行筛选。

5.Methods:Production is finished with the melting by excipient of gelatin and glycerine.

方法：以明胶、甘油为基质，用热融法制备。

6.If necessary, a quick release layer, which is composed of medicines and excipient and covers the outside of the controlled release layer or the slow release layer, can also be included.

如果需要，还包括速释层，由药物及赋形剂组成，包裹在缓释层或控释层外。

7.In pharmaceutical formulations, the role of an excipient (辅料) is crucial for drug stability.

在药物配方中，excipient (辅料) 的作用对药物的稳定性至关重要。

8.The tablet's excipient (辅料) helps to improve its dissolution rate.

该片剂的excipient (辅料) 有助于提高其溶解速率。

9.When developing a new medication, selecting the right excipient (辅料) can affect patient compliance.

在开发新药时，选择合适的excipient (辅料) 会影响患者的依从性。

10.Some excipients (辅料) are designed to enhance the bioavailability of the active ingredient.

一些excipients (辅料) 被设计用于增强活性成分的生物利用度。

11.The excipient (辅料) used in this cream provides a smooth texture for easy application.

这种乳霜中使用的excipient (辅料) 提供了光滑的质地，便于涂抹。

作文

In the field of pharmaceuticals, the term excipient refers to an inactive substance that serves as a carrier for the active ingredients of a medication. These substances are crucial in the formulation of drugs, as they help to deliver the therapeutic effects of the active ingredients while ensuring the stability, bioavailability, and overall effectiveness of the medication. Understanding the role of excipient (辅料) is essential for anyone involved in drug development or those who wish to comprehend how medications are designed and manufactured. When developing a new drug, scientists must consider various factors, including the solubility of the active ingredient, its stability under different conditions, and how it will be absorbed by the body. This is where excipients (辅料) come into play. They can enhance the solubility of poorly soluble drugs, protect sensitive compounds from degradation, and improve the taste of oral medications, making them more palatable for patients. The selection of appropriate excipients (辅料) is a critical step in the formulation process. For instance, lactose is commonly used as a filler in tablets because it is inert, inexpensive, and helps to achieve the desired tablet size and weight. On the other hand, certain polymers may be utilized to control the release rate of the active ingredient, ensuring that it is released slowly over time, which can improve the drug's efficacy and minimize side effects. Moreover, excipients (辅料) can also play a significant role in the manufacturing process. They can influence the flow properties of powders, which is vital for processes like tablet compression. If the flowability of a powder is poor, it can lead to inconsistencies in tablet weight and content uniformity, ultimately affecting the quality of the final product. Therefore, formulators must carefully evaluate the characteristics of potential excipients (辅料) to ensure that they meet the necessary criteria for their specific application. Another important aspect of excipients (辅料) is their regulatory status. Regulatory agencies such as the FDA have established guidelines for the use of excipients (辅料) in drug formulations. These guidelines ensure that all substances used in medications are safe for consumption and do not interfere with the therapeutic effects of the active ingredients. As a result, manufacturers must conduct thorough testing and provide documentation to demonstrate the safety and efficacy of each excipient (辅料) included in their formulations. In conclusion, excipients (辅料) are more than just passive ingredients in pharmaceutical formulations. They play a vital role in the development and manufacturing of drugs, influencing everything from the stability and bioavailability of active ingredients to the overall patient experience. A comprehensive understanding of excipients (辅料) is essential for healthcare professionals, researchers, and patients alike, as it sheds light on the complexities of drug formulation and the importance of each component in achieving optimal therapeutic outcomes.