fibroblasts

简明释义

英[ˈfaɪbroʊˌblæsts]美[ˈfaɪbroʊˌblæsts]

n. [基医]纤维母细胞（fibroblast 的复数）

英英释义

单词用法

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例句

1.Objective To investigate the effect of periphery nerve on fibroblasts during healing process.

目的探讨创伤愈合过程中外周神经对成纤维细胞的影响。

2.The cardiac fibroblasts (CF) are the principal cell type of the heart.

心脏成纤维细胞(CF)是构成心脏的主要细胞类型。

3.Either inadequate or excessive accumulation of fibroblasts could result in abnormal tissue function.

纤维细胞积聚不足或者过多都能导致组织功能异常。

4.P27 could obviously inhibit the synthesis function of hypertrophic scar fibroblasts.

P 27明显抑制增生性瘢痕成纤维细胞的合成功能。

5.Conclusion Periphery nerve can promote fibroblasts proliferation at the early stage of wound.

结论外周感觉神经在创伤后早期可促进成纤维细胞的增殖。

6.Purpose To study the effects of myocardial fibroblasts on fibrosis in diabetic cardiomyopathy.

目的研究成纤维细胞在糖尿病心肌纤维化病变中的作用。

7.AIM: to investigate the effect of selenium chitosan in the growth process of fibroblasts.

目的：观察硒化壳聚糖在成纤维细胞生长过程中的作用。

8.As collagen in the meshwork breaks down, it is replaced and repaired by new collagen secreted by fibroblasts.

随着胶原网打破了，这是更换和修理的新的胶原纤维细胞分泌的。

9.The interstitium was loose in texture, the endothelium of blood vessels was damaged and fibroblasts were edematous.

间质结构松弛，血管上皮缺损及成纤维细胞水肿。

10.In tissue repair, fibroblasts are crucial for synthesizing collagen and extracellular matrix.

在组织修复中，成纤维细胞 对合成胶原蛋白和细胞外基质至关重要。

11.Researchers found that fibroblasts can influence the behavior of immune cells in the tumor microenvironment.

研究人员发现，成纤维细胞 可以影响肿瘤微环境中免疫细胞的行为。

12.When skin is injured, fibroblasts migrate to the wound site to promote healing.

当皮肤受伤时，成纤维细胞 会迁移到伤口部位以促进愈合。

13.The activation of fibroblasts is a key step in the formation of scar tissue.

激活成纤维细胞 是瘢痕组织形成的关键步骤。

14.In culture, fibroblasts exhibit a characteristic spindle shape.

在培养中，成纤维细胞 显示出特征性的纺锤形状。

作文

Fibroblasts are a type of cell that plays a crucial role in the maintenance and repair of connective tissues in the body. They are the most common cells found in connective tissue and are essential for wound healing and tissue regeneration. These cells are responsible for producing collagen, elastin, and other extracellular matrix components that provide structural support to tissues. Understanding the function of fibroblasts (成纤维细胞) is vital for researchers and medical professionals alike, as they are involved in various physiological processes and diseases. In the process of healing, fibroblasts (成纤维细胞) migrate to the site of injury where they proliferate and synthesize collagen. This collagen forms a scaffold that supports new tissue formation. The activity of fibroblasts (成纤维细胞) is regulated by various growth factors and cytokines, which can either stimulate or inhibit their functions. For instance, transforming growth factor-beta (TGF-β) is a key regulator that promotes the proliferation and activation of fibroblasts (成纤维细胞), leading to increased collagen production during the healing process. However, while fibroblasts (成纤维细胞) are essential for normal healing, their dysregulation can lead to pathological conditions. In diseases such as fibrosis, fibroblasts (成纤维细胞) become overactive and produce excessive amounts of collagen, resulting in the thickening and stiffening of tissues. This can impair organ function and lead to serious health issues. Understanding the balance between the normal and pathological activities of fibroblasts (成纤维细胞) is crucial for developing therapeutic strategies to treat fibrotic diseases. Research into fibroblasts (成纤维细胞) has also revealed their involvement in cancer progression. Tumor-associated fibroblasts (成纤维细胞) can promote tumor growth by providing a supportive environment for cancer cells. They secrete growth factors, cytokines, and extracellular matrix components that facilitate tumor invasion and metastasis. Targeting the interactions between cancer cells and fibroblasts (成纤维细胞) is an emerging area of cancer therapy that holds promise for improving patient outcomes. In conclusion, fibroblasts (成纤维细胞) are multifunctional cells that are integral to tissue repair and regeneration. Their ability to produce collagen and other matrix components makes them essential for maintaining the structural integrity of tissues. However, their dysregulation can lead to various diseases, including fibrosis and cancer. Ongoing research into the biology of fibroblasts (成纤维细胞) will not only enhance our understanding of normal physiological processes but also pave the way for novel therapeutic interventions in a range of diseases.

成纤维细胞是一种在身体结缔组织的维持和修复中起关键作用的细胞类型。它们是结缔组织中最常见的细胞，对于伤口愈合和组织再生至关重要。这些细胞负责产生胶原蛋白、弹性蛋白和其他细胞外基质成分，为组织提供结构支持。理解成纤维细胞（fibroblasts）的功能对于研究人员和医学专业人士来说至关重要，因为它们参与各种生理过程和疾病。 在愈合过程中，成纤维细胞（fibroblasts）迁移到损伤部位，在那里增殖并合成胶原蛋白。这种胶原蛋白形成一个支架，支持新组织的形成。成纤维细胞（fibroblasts）的活动受到各种生长因子和细胞因子的调节，这些因子可以刺激或抑制它们的功能。例如，转化生长因子-β（TGF-β）是一个关键调节因子，它促进成纤维细胞（fibroblasts）的增殖和激活，导致在愈合过程中胶原蛋白的增加。 然而，尽管成纤维细胞（fibroblasts）对正常愈合至关重要，但它们的失调可能导致病理状况。在纤维化等疾病中，成纤维细胞（fibroblasts）变得过度活跃，产生过量的胶原蛋白，导致组织增厚和僵硬。这会损害器官功能并导致严重的健康问题。理解成纤维细胞（fibroblasts）正常活动与病理活动之间的平衡对于开发治疗纤维化疾病的策略至关重要。 对成纤维细胞（fibroblasts）的研究还揭示了它们在癌症进展中的作用。肿瘤相关的成纤维细胞（fibroblasts）可以通过为癌细胞提供支持环境来促进肿瘤生长。它们分泌生长因子、细胞因子和细胞外基质成分，促进肿瘤侵袭和转移。靶向癌细胞与成纤维细胞（fibroblasts）之间的相互作用是癌症疗法的一个新兴领域，具有改善患者预后的潜力。 总之，成纤维细胞（fibroblasts）是多功能细胞，对于组织的修复和再生至关重要。它们产生胶原蛋白和其他基质成分的能力使它们对维持组织的结构完整性不可或缺。然而，它们的失调可能导致各种疾病，包括纤维化和癌症。对成纤维细胞（fibroblasts）生物学的持续研究不仅将增强我们对正常生理过程的理解，还将为一系列疾病中新型治疗干预措施铺平道路。