fibroblast

简明释义

英[ˈfaɪbrəʊˌblæst]美[ˈfaɪbrəblæst]

n. [基医] 纤维原细胞；纤维组织母细胞

英英释义

单词用法

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例句

1.PGC from genital ridge and mesenterium of human embryo was incubated on fibroblast feeder layers for subculture.

从人胚胎生殖嵴、肠系膜中消化分离的原始生殖细胞，将其接种在人子宫内膜成纤维细胞饲养层上传代培养。

2.The differences of fibroblast properties were also present in different wound repair.

成纤维细胞内在特性在不同的创伤修复过程中也有所不同。

3.Objective To evaluate the influence of verapamil on gingival fibroblast migration.

目的评价维拉·帕米对牙龈成纤维细胞移出的影响。

4.Objective: the effect of basic fibroblast growth factor on the peripheral nerve was studied.

目的：探讨碱性成纤维细胞生长因子对神经再生的影响。

5.Objective To study the role of fibroblast in aseptic loosening.

目的探讨成纤维细胞在无菌性松动中的作用。

6.RESULTS: Cranial neural crest cells were cultured successfully. The shape of the cells were fibroblast-like.

结果：成功地培养出小鼠的颅神经嵴细胞，其形态类似成纤维样细胞。

7.Objective: To investigate the effect of basic fibroblast growth factor on matrix metalloproteinases and restenosis after PTCA .

目的：探讨碱性成纤维细胞生长因子对基质金属蛋白酶表达的影响及其在球囊术后再狭窄中的作用。

8.The role of the fibroblast 成纤维细胞 in wound healing is crucial for tissue regeneration.

在伤口愈合中，成纤维细胞的作用对组织再生至关重要。

9.Researchers found that fibroblast 成纤维细胞 activity increases during the inflammatory response.

研究人员发现，在炎症反应期间，成纤维细胞的活性增加。

10.In skin biopsies, the density of fibroblast 成纤维细胞 can indicate the severity of fibrosis.

在皮肤活检中，成纤维细胞的密度可以指示纤维化的严重程度。

11.A healthy fibroblast 成纤维细胞 population is essential for maintaining skin elasticity.

健康的成纤维细胞群体对维持皮肤弹性至关重要。

12.Studies show that fibroblast 成纤维细胞 contribute to collagen production in connective tissues.

研究表明，成纤维细胞有助于结缔组织中的胶原蛋白生产。

作文

In the realm of cellular biology, understanding the various types of cells and their functions is crucial. One type of cell that plays a significant role in the maintenance and repair of tissues is the fibroblast. The fibroblast (成纤维细胞) is a type of cell that synthesizes the extracellular matrix and collagen, which are vital for the structural integrity of tissues. These cells are primarily found in connective tissues, where they produce and secrete proteins that provide support to other cells and tissues in the body. Fibroblasts are not just passive components of the tissue; they are highly active cells that respond to injury and inflammation. When tissue is damaged, fibroblasts (成纤维细胞) migrate to the site of injury and start the healing process. They proliferate and produce collagen fibers, which help to form a scar and restore the structural framework of the tissue. This process is essential for wound healing, as it ensures that the tissue can regain its strength and functionality. Moreover, fibroblasts (成纤维细胞) also play a role in regulating the immune response. They can release various signaling molecules that attract immune cells to the site of injury, thus facilitating the healing process. This interaction between fibroblasts (成纤维细胞) and the immune system highlights their importance not only in tissue repair but also in maintaining homeostasis within the body. Interestingly, fibroblasts (成纤维细胞) can also differentiate into other cell types under certain conditions. For instance, in the presence of specific growth factors, fibroblasts (成纤维细胞) can transform into myofibroblasts, which have contractile properties and are involved in wound contraction during the healing process. This ability to change their function underscores the versatility and adaptability of fibroblasts (成纤维细胞). In addition to their role in normal physiological processes, fibroblasts (成纤维细胞) are also implicated in various pathological conditions. For example, in fibrotic diseases, fibroblasts (成纤维细胞) become overactive and produce excessive amounts of collagen, leading to tissue stiffness and impaired function. Understanding the mechanisms that regulate fibroblast (成纤维细胞) activity is therefore crucial for developing therapeutic strategies to treat such disorders. In conclusion, fibroblasts (成纤维细胞) are essential cells in the body that contribute significantly to tissue maintenance, repair, and immune regulation. Their ability to respond to injury and adapt to different physiological demands makes them a fascinating subject of study in cellular biology. By further exploring the functions and mechanisms of fibroblasts (成纤维细胞), researchers can gain insights into not only normal healing processes but also the development of various diseases, paving the way for innovative treatments in regenerative medicine.

在细胞生物学领域，理解各种细胞及其功能至关重要。一个在组织维护和修复中发挥重要作用的细胞类型是成纤维细胞。成纤维细胞是一种合成细胞外基质和胶原蛋白的细胞，这对组织的结构完整性至关重要。这些细胞主要存在于结缔组织中，在那里它们产生和分泌为其他细胞和组织提供支持的蛋白质。 成纤维细胞不仅是组织的被动组成部分；它们是高度活跃的细胞，会对伤害和炎症作出反应。当组织受损时，成纤维细胞会迁移到损伤部位并启动愈合过程。它们增殖并产生胶原纤维，这有助于形成瘢痕并恢复组织的结构框架。这个过程对伤口愈合至关重要，因为它确保组织能够恢复其强度和功能。 此外，成纤维细胞还在调节免疫反应中发挥作用。它们可以释放各种信号分子，吸引免疫细胞到达损伤部位，从而促进愈合过程。成纤维细胞与免疫系统之间的这种相互作用突显了它们在组织修复和维持体内稳态中的重要性。 有趣的是，成纤维细胞在某些条件下也可以分化为其他细胞类型。例如，在特定生长因子的存在下，成纤维细胞可以转变为肌成纤维细胞，这些细胞具有收缩特性，并参与愈合过程中的伤口收缩。这种改变功能的能力强调了成纤维细胞的多功能性和适应性。 除了在正常生理过程中发挥作用外，成纤维细胞还与各种病理状况有关。例如，在纤维化疾病中，成纤维细胞变得过于活跃，产生过量的胶原蛋白，导致组织僵硬和功能受损。因此，了解调节成纤维细胞活动的机制对于开发治疗这些疾病的策略至关重要。 总之，成纤维细胞是体内必不可少的细胞，对组织的维护、修复和免疫调节做出了重要贡献。它们对伤害的反应能力和适应不同生理需求的能力使它们成为细胞生物学研究中一个引人入胜的主题。通过进一步探索成纤维细胞的功能和机制，研究人员可以深入了解正常愈合过程以及各种疾病的发展，为再生医学中的创新治疗铺平道路。