filopodium

简明释义

英[ˌfɪləˈpoʊdiəm]美[ˌfɪləˈpoʊdiəm]

n. 外肉伪足（根足虫的）

复 数 f i l o p o d i a

英英释义

单词用法

同义词

反义词

例句

1.The neuron extends a filopodium to explore its environment.

神经元伸出一个细足来探索其环境。

2.In the study of cell migration, researchers observed that the filopodium plays a crucial role in sensing the extracellular matrix.

在细胞迁移的研究中，研究人员观察到细足在感知细胞外基质中起着至关重要的作用。

3.The growth cone of the axon is characterized by the presence of multiple filopodia extending outward.

轴突的生长锥以多个向外延伸的细足为特征。

4.During embryonic development, filopodia help guide cells to their correct locations.

在胚胎发育过程中，细足帮助引导细胞到达正确的位置。

5.The interaction between two cells can be mediated by the formation of filopodia that connect them.

两个细胞之间的相互作用可以通过形成连接它们的细足来介导。

作文

In the intricate world of cellular biology, the term filopodium refers to slender, finger-like projections that extend from the surface of a cell. These structures are primarily involved in sensing the environment and facilitating cell movement. Understanding the role of filopodium is crucial for comprehending how cells interact with their surroundings and navigate through complex biological systems. Cells, the fundamental units of life, exhibit remarkable abilities to adapt and respond to external stimuli. One of the ways they achieve this is through the formation of filopodia. These extensions are composed of actin filaments and are often found at the leading edge of migrating cells. For instance, during the process of wound healing, cells will extend filopodia to explore the extracellular matrix, allowing them to find the optimal path for migration. The mechanisms behind the formation of filopodia involve a variety of signaling pathways. When a cell encounters a chemical gradient, it can initiate the polymerization of actin, leading to the protrusion of filopodia. This process is not only vital for cell migration but also plays a significant role in cellular communication. By extending filopodia, cells can make contact with neighboring cells, facilitating the exchange of information and promoting tissue organization. Moreover, filopodia are essential during embryonic development. They guide the movement of cells as they migrate to their designated locations, ensuring proper formation of tissues and organs. Disruptions in the formation or function of filopodia can lead to developmental abnormalities and diseases, highlighting their importance in maintaining cellular integrity. In addition to their role in migration and development, filopodia are also involved in processes such as synaptogenesis in neurons. In the nervous system, filopodia can help establish connections between neurons, forming synapses that are crucial for transmitting signals. This underscores the versatility of filopodia beyond mere cell movement—they are integral to the formation of complex networks within multicellular organisms. Research on filopodia has expanded significantly in recent years, revealing their involvement in various pathological conditions. For example, cancer cells often exhibit enhanced filopodia formation, which aids in their invasive capabilities. By understanding the molecular mechanisms that regulate filopodia, scientists hope to develop targeted therapies that can inhibit cancer metastasis. In conclusion, filopodium is a vital component of cellular architecture, playing critical roles in movement, communication, and development. Its study not only enhances our understanding of basic biological processes but also opens avenues for therapeutic interventions in diseases where cell migration and communication are disrupted. As we continue to explore the multifaceted functions of filopodia, we gain deeper insights into the complexities of life at the cellular level.

在细胞生物学的复杂世界中，术语filopodium指的是从细胞表面延伸出来的细长、类似手指的突起。这些结构主要参与感知环境和促进细胞运动。理解filopodium的作用对于理解细胞如何与周围环境相互作用以及如何在复杂的生物系统中导航至关重要。 细胞是生命的基本单位，展现出惊人的适应能力和对外部刺激的反应能力。它们通过形成filopodia来实现这一点。这些突起由肌动蛋白丝组成，通常位于迁移细胞的前缘。例如，在伤口愈合过程中，细胞会伸展filopodia以探索细胞外基质，使其能够找到最佳的迁移路径。 filopodia形成背后的机制涉及多种信号通路。当细胞遇到化学梯度时，它可以启动肌动蛋白的聚合，导致filopodia的突出。这个过程不仅对细胞迁移至关重要，而且在细胞间通信中也发挥着重要作用。通过伸展filopodia，细胞可以与邻近细胞接触，促进信息的交换并促进组织的形成。 此外，filopodia在胚胎发育过程中也至关重要。它们指导细胞的运动，使其迁移到指定位置，确保组织和器官的正确形成。filopodia的形成或功能的干扰可能导致发育异常和疾病，突显了它们在维持细胞完整性方面的重要性。 除了在迁移和发育中的作用外，filopodia还参与神经元的突触发生。在神经系统中，filopodia可以帮助建立神经元之间的连接，形成对传递信号至关重要的突触。这强调了filopodia在多细胞生物体内超越单纯细胞运动的多样性——它们对复杂网络的形成至关重要。 近年来，对filopodia的研究显著增加，揭示了它们在各种病理条件中的参与。例如，癌细胞通常表现出增强的filopodia形成，这有助于它们的侵袭能力。通过理解调节filopodia的分子机制，科学家希望开发针对性疗法，以抑制癌症转移。 总之，filopodium是细胞结构的重要组成部分，在运动、通信和发育中发挥着关键作用。它的研究不仅增强了我们对基本生物过程的理解，还为在细胞迁移和通信受损的疾病中进行治疗干预开辟了途径。随着我们继续探索filopodia的多方面功能，我们将更深入地了解细胞水平上生命的复杂性。