ganglioside

简明释义

英[ˈɡæŋɡlɪəʊˌsaɪd]美[ˈɡæŋɡliəˌsaɪd]

n. [生化] 神经节苷脂

英英释义

单词用法

同义词

反义词

例句

1.The kinetic study of the incorporation of exogenous ganglioside GM3 into the lipid bilayer of rabbit sarcoplasmic reticulum (SR) was carried out by trace extraction of Gls and high performance TLC.

用微量提取和高效薄板层析方法研究了外源性神经节苷脂GM3掺入兔肌质网膜的动力学过程。

2.The kinetic study of the incorporation of exogenous ganglioside GM3 into the lipid bilayer of rabbit sarcoplasmic reticulum (SR) was carried out by trace extraction of Gls and high performance TLC.

用微量提取和高效薄板层析方法研究了外源性神经节苷脂GM3掺入兔肌质网膜的动力学过程。

3.Ganglioside GM3 has been proved to be a physiological cell differentiation inducer in several human leukemia cell lines. However, the inducing differentiation mechanism of GM3 remains unclear.

神经节苷脂gm3作为一种促分化剂已在多个细胞瘤株模型中得到证实，但迄今为止其促分化的详细机制仍未阐明。

4.Objective: To study the clinical value of anti-cardiolipin antibodies(ACA) and anti- ganglioside antibodies (AGA) in people with neuropsychiatric lupus erythematosus (NPLE).

目的：探讨抗神经节苷脂抗体与抗心磷脂抗体在神经精神性狼疮中的意义。

5.CONCLUSION: in immune-mediated nerve diseases, the detection of anti-ganglioside antibodies is significantly useful to clinical auxiliary diagnosis and effect-analysis.

结论：在免疫介导的神经疾病中，抗神经节苷脂抗体的检测对辅助诊断、分析疗效有重要的临床意义。

6.Objective to study the distribution of antibody against GM1 ganglioside in serum and CSF, and to probe into its pathogenetic role in motor neuron disease (MND).

目的分析运动神经元疾病(MND)患者血清和脑脊液中神经节苷脂(GM1)抗体的分布，研究其在MND发病过程中的作用。

7.Objective To investigate clinical efficacy of the ganglioside (GM1) treating neonatal hypoxic-ischemic encephalopathy (HIE).

目的探讨神经节苷脂(GM1)治疗新生儿缺氧缺血性脑病(HIE)的临床疗效。

8.AIM: To study the effect of GM1 ganglioside (GM1) on learning and memory disorders in rats with brain radiation.

目的：研究神经节苷酯(GM1)对脑放射后学习记忆能力减退鼠空间学习记忆的影响。

9.The role of ganglioside GM1 is increasingly concerned in cerebrovascular diseases.

神经节苷脂GM1在脑血管病中的作用日益受到重视。

10.Objective To investigate the mechanism of Ganglioside on acute cord injury.

目的探讨神经节苷酯治疗急性脊髓损伤的机制。

11.The research focused on the role of ganglioside in neuronal signaling.

这项研究集中在神经节苷脂在神经信号传递中的作用。

12.Elevated levels of ganglioside have been linked to certain neurodegenerative diseases.

升高的神经节苷脂水平与某些神经退行性疾病有关。

13.In immunology, ganglioside can act as a target for autoimmune responses.

在免疫学中，神经节苷脂可以作为自身免疫反应的靶标。

14.Researchers are studying how ganglioside affects cell membrane fluidity.

研究人员正在研究神经节苷脂如何影响细胞膜的流动性。

15.Certain bacterial infections can alter the levels of ganglioside in host cells.

某些细菌感染可以改变宿主细胞中神经节苷脂的水平。

作文

Gangliosides are complex molecules that play a crucial role in the functioning of the nervous system. These glycosphingolipids are found in the outer membrane of nerve cells and are essential for cell communication and signaling. The structure of a ganglioside consists of a sphingosine backbone, a fatty acid chain, and one or more sugar residues, including sialic acid. This unique composition gives gangliosides their distinctive properties and functions. One of the most important roles of gangliosides is their involvement in cell recognition and adhesion. They act as receptors for various ligands, which helps in the communication between neurons. This is particularly important during the development of the nervous system, where gangliosides guide the growth of axons and the formation of synapses. In addition, gangliosides are involved in modulating the activity of neurotransmitters, thereby influencing neuronal excitability and plasticity. Research has shown that alterations in the levels of gangliosides can be associated with several neurological disorders. For instance, an increase in certain types of gangliosides has been linked to neurodegenerative diseases such as Alzheimer's and Parkinson's disease. This suggests that maintaining a proper balance of gangliosides is vital for brain health. Moreover, gangliosides have also been studied for their potential therapeutic applications. Some studies indicate that they could be used in developing treatments for conditions such as multiple sclerosis and other autoimmune diseases, where the immune system attacks the nervous system. In addition to their role in the nervous system, gangliosides are also important in other biological processes. They are involved in cell growth, differentiation, and apoptosis (programmed cell death). This highlights their significance not only in neural tissues but also in various other cell types throughout the body. Furthermore, gangliosides are present in different tissues and organs, suggesting that they may have diverse functions beyond the nervous system. Understanding the biology of gangliosides is crucial for advancing our knowledge of cellular processes and developing new therapeutic strategies. Researchers are increasingly focusing on the molecular mechanisms by which gangliosides exert their effects. This includes studying how they interact with proteins and other molecules within the cell membrane, which can lead to insights into how cells communicate and respond to their environment. In conclusion, gangliosides are essential components of the nervous system, playing critical roles in cell communication, signaling, and overall brain function. Their involvement in various neurological disorders makes them a significant area of research in neuroscience. As we continue to explore the functions and mechanisms of gangliosides, we may uncover new pathways for treatment and intervention in a range of neurological conditions. The study of gangliosides not only enhances our understanding of cellular biology but also opens up possibilities for innovative therapeutic approaches in medicine.

神经节苷脂是复杂的分子，在神经系统的功能中起着至关重要的作用。这些糖鞘脂存在于神经细胞的外膜中，对于细胞之间的通信和信号传递是必不可少的。ganglioside的结构由一个鞘氨醇骨架、一个脂肪酸链和一个或多个糖残基（包括唾液酸）组成。这种独特的组成赋予了ganglioside其独特的特性和功能。 ganglioside最重要的角色之一是参与细胞识别和粘附。它们充当各种配体的受体，帮助神经元之间的沟通。这在神经系统的发展过程中尤为重要，因为ganglioside引导轴突的生长和突触的形成。此外，ganglioside还参与调节神经递质的活性，从而影响神经元的兴奋性和可塑性。 研究表明，ganglioside水平的变化可能与多种神经系统疾病相关。例如，某些类型的ganglioside增加与阿尔茨海默病和帕金森病等神经退行性疾病有关。这表明维持ganglioside的适当平衡对大脑健康至关重要。此外，ganglioside也被研究用于潜在的治疗应用。一些研究表明，它们可以用于开发治疗多发性硬化症和其他自身免疫性疾病的药物，这些疾病中免疫系统攻击神经系统。 除了在神经系统中的作用外，ganglioside在其他生物过程中也很重要。它们参与细胞生长、分化和凋亡（程序性细胞死亡）。这突显了它们不仅在神经组织中，而且在全身各种其他细胞类型中的重要性。此外，ganglioside存在于不同的组织和器官中，表明它们可能在神经系统之外具有多样的功能。 理解ganglioside的生物学对于推进我们对细胞过程的认识和开发新的治疗策略至关重要。研究人员越来越关注ganglioside发挥作用的分子机制。这包括研究它们如何与细胞膜内的蛋白质和其他分子相互作用，这可以揭示细胞如何沟通和响应其环境的见解。 总之，ganglioside是神经系统的重要成分，在细胞通信、信号传递和整体大脑功能中发挥关键作用。它们在各种神经系统疾病中的参与使它们成为神经科学研究的重要领域。随着我们继续探索ganglioside的功能和机制，我们可能会发现新的治疗和干预途径，以应对一系列神经系统疾病。对ganglioside的研究不仅增强了我们对细胞生物学的理解，还为医学中的创新治疗方法开辟了可能性。