glycolytic

简明释义

英[ˌɡlaɪkəʊˈlɪtɪk]美[ˌɡlaɪkəˈlɪtɪk]

adj. 糖分解的

英英释义

单词用法

同义词

反义词

例句

1.Glycolytic reaction which provides energy for life is very important to maintain life.

糖酵解过程是为生命提供能量的过程，对维持生命起关键作用。

2.NSE is proved to be an important enzyme involved in the glycolytic pathway and is closely related to the energy supply for brain.

NSE是糖酵解途径中重要的酶，它与脑中能量的供应密切相关。

3.Inherited deficiency of pyruvate kinase, a key glycolytic enzyme, causes ATP deficiency, which leads to reduced RBC life span and hemolytic anemia.

糖酵解的关键酶——丙酮酸激酶，如果它有遗传缺陷，就导致会atp缺乏、红细胞寿命缩短和溶血性贫血。

4.Glycerol obtained from the breakdown of fat is metabolized by conversion to dihydroxyacetone phosphate, a glycolytic intermediate, in two enzyme-catalyzed reactions.

来源于脂肪的甘油经两步酶促反应代谢转化为糖酵解的中间产物磷酸二羟丙酮。

5.Conclusion in the early stage of diabetes, Mg supplementation can improve the activities of the crucial rate limiting enzymes relating to glycolytic pathway of diabetic retinal tissue in rats.

结论在糖尿病发病后的一段时期内，补充镁可提高视网膜糖酵解限速酶的活性。

6.It was proved that the metabolism of conductive tissue is glycolytic.

表明传导组织是以无氧代谢为其主要代谢途径。

7.The results indicated that phosphorylase and LDH, the key enzyme in glycolytic metabolism, are high positive in conductive tissue of heart, and the myocardium are a slightly highher activity.

结果显示，直接参与细胞无氧代谢的磷酸化酶和LDH在传导组织细胞内呈强阳性反应，心肌为弱阳性。

8.A thermophilic anaerobic glycolytic bacterium was isolated from the hot spring of Kang Ding County of Sichuan Province.

从四川省康定县热温泉分离出一株嗜热厌氧糖酵解细菌。

9.The process of energy production in muscles during intense exercise is primarily due to glycolytic 糖酵解的 pathways.

在剧烈运动中，肌肉能量产生的过程主要归功于glycolytic 糖酵解的途径。

10.Cancer cells often rely on glycolytic 糖酵解的 metabolism for rapid growth and proliferation.

癌细胞通常依赖于glycolytic 糖酵解的代谢来快速生长和繁殖。

11.In anaerobic conditions, our body switches to glycolytic 糖酵解的 pathways to generate ATP.

在厌氧条件下，我们的身体转向glycolytic 糖酵解的途径来生成ATP。

12.A high-intensity workout typically engages the glycolytic 糖酵解的 system more than aerobic pathways.

高强度的锻炼通常比有氧途径更能激活glycolytic 糖酵解的系统。

13.Research shows that glycolytic 糖酵解的 enzymes play a crucial role in metabolic disorders.

研究表明，glycolytic 糖酵解的酶在代谢性疾病中发挥着关键作用。

作文

The process of energy production in living organisms is a complex and fascinating subject. One of the key pathways involved in this process is known as the glycolytic pathway. This pathway plays a crucial role in breaking down glucose to produce energy in the form of ATP (adenosine triphosphate). Understanding the glycolytic process is essential for anyone studying biology, biochemistry, or medicine, as it lays the foundation for comprehending how cells generate energy and how various metabolic disorders can arise. The glycolytic pathway occurs in the cytoplasm of the cell and consists of a series of ten enzymatic reactions. It begins with the phosphorylation of glucose, which is then converted into fructose-1,6-bisphosphate. This molecule is subsequently split into two three-carbon molecules, called glyceraldehyde-3-phosphate (G3P). Through a series of transformations, these molecules are ultimately converted into pyruvate, with the simultaneous production of ATP and NADH. The net gain from one molecule of glucose undergoing glycolytic metabolism is two molecules of ATP, which is a relatively small amount compared to what can be generated through aerobic respiration. One of the most interesting aspects of the glycolytic pathway is its versatility. It can function in both aerobic and anaerobic conditions. In the presence of oxygen, pyruvate produced from glycolytic metabolism is further processed in the mitochondria through the citric acid cycle and oxidative phosphorylation, leading to a much higher yield of ATP. However, in the absence of oxygen, cells can convert pyruvate into lactate through fermentation, allowing glycolysis to continue producing ATP even when oxygen levels are low. The regulation of the glycolytic pathway is also an area of significant interest. Several enzymes in this pathway are subject to allosteric regulation and feedback inhibition, allowing the cell to respond to its energy needs. For instance, when ATP levels are high, the enzyme phosphofructokinase, which catalyzes one of the key steps in the glycolytic pathway, is inhibited. Conversely, when ATP levels drop, this enzyme is activated, promoting glycolysis to increase ATP production. Moreover, the glycolytic pathway has been implicated in various diseases, including cancer. Cancer cells often exhibit a phenomenon known as the Warburg effect, where they rely heavily on glycolytic metabolism for energy production even in the presence of oxygen. This shift allows cancer cells to rapidly proliferate, making them more aggressive. Understanding these metabolic changes has opened new avenues for targeted therapies aimed at disrupting the glycolytic pathway in cancer treatment. In conclusion, the glycolytic pathway is a vital metabolic route that provides energy to cells under various conditions. Its intricate mechanisms and regulatory processes highlight the complexity of cellular metabolism and its importance in health and disease. As research continues to evolve, the insights gained from studying the glycolytic pathway will undoubtedly contribute to advancements in medical science and our understanding of life itself.

在生物体内，能量产生的过程是一个复杂而迷人的主题。参与这个过程的关键途径之一被称为糖酵解途径。该途径在分解葡萄糖以产生ATP（腺苷三磷酸）形式的能量中发挥着至关重要的作用。理解糖酵解过程对于任何学习生物学、生物化学或医学的人来说都是必不可少的，因为它为理解细胞如何产生能量以及如何产生各种代谢紊乱奠定了基础。 糖酵解途径发生在细胞的细胞质中，由十个酶促反应组成。它以葡萄糖的磷酸化开始，随后转化为果糖-1,6-二磷酸。这个分子随后被分裂成两个三碳分子，称为甘油醛-3-磷酸（G3P）。通过一系列转化，这些分子最终被转化为丙酮酸，同时产生ATP和NADH。每一分子葡萄糖经过糖酵解代谢的净收益为两分子ATP，这与通过有氧呼吸所产生的ATP相比，相对较少。 糖酵解途径最有趣的方面之一是它的多功能性。它可以在有氧和无氧条件下发挥作用。在氧气存在的情况下，由糖酵解代谢产生的丙酮酸进一步在线粒体中通过柠檬酸循环和氧化磷酸化进行处理，从而导致更高的ATP产量。然而，在缺氧的情况下，细胞可以通过发酵将丙酮酸转化为乳酸，使得糖酵解在氧气水平低的情况下继续产生ATP。 糖酵解途径的调节也是一个重要的研究领域。该途径中的几个酶受到别构调节和反馈抑制的影响，使细胞能够响应其能量需求。例如，当ATP水平高时，催化糖酵解途径中一个关键步骤的酶磷酸果糖激酶会被抑制。相反，当ATP水平下降时，该酶被激活，促进糖酵解以增加ATP生产。 此外，糖酵解途径还与多种疾病有关，包括癌症。癌细胞通常表现出一种被称为瓦尔堡效应的现象，即即使在氧气存在的情况下，它们也严重依赖糖酵解代谢进行能量生产。这种转变使癌细胞能够快速增殖，使其更加侵袭性。理解这些代谢变化为针对癌症治疗的靶向疗法开辟了新的途径，旨在破坏糖酵解途径。 总之，糖酵解途径是一个重要的代谢途径，为细胞在各种条件下提供能量。其复杂的机制和调节过程突显了细胞代谢的复杂性及其在健康和疾病中的重要性。随着研究的不断发展，从研究糖酵解途径中获得的见解无疑将为医学科学的进步和我们对生命本身的理解做出贡献。