glycopeptides

简明释义

英[ˌɡlaɪkoʊˈpɛptaɪdz]美[ˌɡlaɪkoʊˈpɛptaɪdz]

糖肽类

英英释义

单词用法

同义词

反义词

例句

1.There are two available strategies recently for the solid-phase synthesis of glycopeptides: The building block strategy and solid-phase glycosylation strategy.

目前糖肽的固相合成可以分为两种策略：构建单元策略和固相糖基化策略。

2.There are two available strategies recently for the solid-phase synthesis of glycopeptides: The building block strategy and solid-phase glycosylation strategy.

目前糖肽的固相合成可以分为两种策略：构建单元策略和固相糖基化策略。

3.Objective: This study was to probe into the antimetastasis mechanism of pig red cell membrane glycopeptides (PRCMG).

目的：探讨猪红细胞膜糖肽抗肿瘤转移的作用机制。

4.The resistance of MRSA is very severer, which can be treated effectively only by Glycopeptides antibiotics.

MRSA的耐药性非常严重，万古霉素等糖肽类抗生素是唯一有效的抗菌药物。

5.Researchers are studying the mechanisms of action of glycopeptides in antibiotic resistance.

研究人员正在研究糖肽在抗生素耐药性中的作用机制。

6.The new drug developed is a type of glycopeptides that targets Gram-positive bacteria.

新开发的药物是一种针对革兰阳性细菌的糖肽。

7.Clinicians often prescribe glycopeptides for serious infections caused by resistant strains.

临床医生经常为由耐药菌株引起的严重感染开处方糖肽。

8.The side effects of glycopeptides should be monitored closely during treatment.

治疗期间应密切监测糖肽的副作用。

9.In laboratory tests, glycopeptides showed significant efficacy against MRSA.

在实验室测试中，糖肽对耐甲氧西林金黄色葡萄球菌（MRSA）表现出显著的疗效。

作文

In recent years, the field of medicine has witnessed significant advancements, particularly in the development of new antibiotics. One class of antibiotics that has garnered attention is glycopeptides, which are crucial in treating serious bacterial infections. These compounds are derived from certain species of bacteria and possess unique properties that make them effective against Gram-positive bacteria. The mechanism of action of glycopeptides involves inhibiting cell wall synthesis, which ultimately leads to the death of the bacteria. This is particularly important in an era where antibiotic resistance is becoming a major concern. Glycopeptides include well-known antibiotics such as vancomycin and teicoplanin. Vancomycin, for instance, has been a cornerstone in the treatment of infections caused by methicillin-resistant Staphylococcus aureus (MRSA). Its discovery and subsequent use have saved countless lives, especially in hospital settings where resistant strains of bacteria are prevalent. The ability of glycopeptides to target these resistant bacteria highlights their importance in modern medicine. However, the use of glycopeptides is not without challenges. One major issue is the potential for nephrotoxicity, which can occur with high doses or prolonged use. This side effect necessitates careful monitoring of kidney function in patients receiving glycopeptides. Additionally, the emergence of resistance to glycopeptides itself, although still relatively rare, poses a threat that could limit their effectiveness in the future. Researchers are actively investigating ways to overcome these challenges, including the development of novel glycopeptides that may have enhanced efficacy and reduced toxicity. The importance of glycopeptides extends beyond their clinical applications; they also serve as a valuable tool in research. Scientists study these compounds to better understand bacterial physiology and the mechanisms of antibiotic action. By examining how glycopeptides interact with bacterial cells, researchers can gain insights into new therapeutic strategies that may combat antibiotic resistance. Furthermore, the structural complexity of glycopeptides makes them interesting subjects for the study of drug design and synthesis. In conclusion, glycopeptides represent a vital component of our antibiotic arsenal, particularly in the fight against resistant bacterial infections. Their unique mechanisms and therapeutic potential underscore the need for ongoing research and development in this area. As we face the growing challenge of antibiotic resistance, understanding and utilizing glycopeptides effectively will be crucial in preserving their efficacy for future generations. The continued exploration of these compounds promises not only to enhance our treatment options but also to deepen our understanding of microbial biology and the intricate battle between bacteria and antibiotics.

近年来，医学领域见证了显著的进步，特别是在新抗生素的开发方面。其中一个备受关注的抗生素类别是糖肽，它们在治疗严重细菌感染中至关重要。这些化合物源自某些种类的细菌，具有独特的特性，使其对革兰氏阳性细菌有效。糖肽的作用机制涉及抑制细胞壁合成，最终导致细菌死亡。在抗生素耐药性成为主要问题的时代，这一点尤为重要。 糖肽包括一些知名的抗生素，如万古霉素和替考拉宁。例如，万古霉素在治疗由耐甲氧西林金黄色葡萄球菌（MRSA）引起的感染方面一直是基石。它的发现和随后的使用挽救了无数生命，特别是在耐药菌株普遍存在的医院环境中。糖肽能够针对这些耐药细菌，突显了它们在现代医学中的重要性。 然而，使用糖肽并非没有挑战。一个主要问题是可能出现的肾毒性，这可能发生在高剂量或长期使用的情况下。这种副作用需要在接受糖肽治疗的患者中仔细监测肾功能。此外，尽管仍然相对少见，但对糖肽本身的耐药性出现也构成威胁，可能限制其在未来的有效性。研究人员正在积极调查克服这些挑战的方法，包括开发新的糖肽，可能具有增强的疗效和减少的毒性。 糖肽的重要性不仅体现在临床应用中；它们也是研究中的宝贵工具。科学家研究这些化合物，以更好地理解细菌生理学和抗生素作用机制。通过检查糖肽如何与细菌细胞相互作用，研究人员可以深入了解可能对抗抗生素耐药性的新的治疗策略。此外，糖肽的结构复杂性使它们成为药物设计和合成研究的有趣主题。 总之，糖肽代表了我们抗生素武器库中的一个重要组成部分，尤其是在与耐药细菌感染的斗争中。它们独特的机制和治疗潜力强调了在这一领域持续研究和发展的必要性。随着我们面临抗生素耐药性日益增长的挑战，有效理解和利用糖肽将对保护其未来的有效性至关重要。对这些化合物的持续探索不仅承诺增强我们的治疗选择，还将加深我们对微生物生物学的理解，以及细菌与抗生素之间错综复杂的斗争。