hemosiderin

简明释义

英[ˌhiːməʊˈsɪdərɪn]美[ˌhiːmoʊˈsɪdərɪn]

n. 血铁质；[生化] 血铁黄素

英英释义

单词用法

同义词

反义词

例句

1.The breakdown of the blood into hemosiderin has led to brownish staining of some of the cysts seen here.

血管破坏出血形成的含血铁黄素使一些包囊染成褐色。

2.A Pruian blue reaction is seen in this iron stain of the liver to demotrate large amounts of hemosiderin that are present in hepatocytes and…

肝细胞及库普弗细胞含铁血黄素沉着肝脏普鲁士蓝染色呈蓝色的含铁血黄素颗粒大量沉着在肝实质细胞和库普弗细胞内。

3.Iron is released from the heme moiety and either stored in the macrophage as ferritin or hemosiderin, or released into the circulation for transport back to the marrow.

铁元素从血红素中释放出来，要么转化为巨噬细胞中的铁蛋白或含铁血黄素，或通过血液循环回流进入骨髓。

4.These renal tubules contain large amounts of hemosiderin, as demotrated by an iron stain.

肾小管含铁血黄素颗粒沉着图示：肾小管内含有大量含铁血黄素颗粒。

5.These renal tubules contain large amounts of hemosiderin, as demonstrated by an iron stain.

肾小管内含有大量含铁血黄素颗粒。

6.There can be hemosiderin pigment from hemorrhage as well.

也可出现出血形成的含铁血黄素。

7.The hemosiderin from the hemorrhage produces the grossly brown color.

出血形成的血铁黄素使病变肉眼观察呈深棕色。

8.These renal tubules contain large amounts of hemosiderin, as demonstrated by an iron stain.

图示：肾小管内含有大量含铁血黄素颗粒。

9.Plenty of macrophages were gathered together, resulting in cellular outline to be ambiguous, which phagocytosised amounts of hemosiderin granules.

大量吞噬有含铁血黄素颗粒的巨噬细胞聚集在一起，连成一片，致使细胞轮廓不清；

10.The presence of hemosiderin indicates iron overload in the body.

存在血铁素表明体内铁过载。

11.A biopsy revealed deposits of hemosiderin in the liver tissue.

活检显示肝组织中有血铁素沉积。

12.Patients with chronic hemolytic anemia often have increased levels of hemosiderin.

慢性溶血性贫血患者通常有较高的血铁素水平。

13.The pathologist noted significant hemosiderin accumulation in the spleen.

病理学家注意到脾脏中有显著的血铁素积累。

14.Excessive hemosiderin can lead to organ damage over time.

过量的血铁素会随着时间的推移导致器官损伤。

作文

Hemosiderin is a complex protein that plays a crucial role in iron metabolism within the human body. This substance is primarily formed from the breakdown of hemoglobin, which is the protein found in red blood cells responsible for transporting oxygen. When red blood cells are destroyed, iron is released and can be stored in various forms, one of which is hemosiderin (铁蛋白). Unlike ferritin, another iron-storage protein, hemosiderin (铁蛋白) is less soluble and is typically found in tissues where there is an excess of iron. The accumulation of hemosiderin (铁蛋白) can occur due to several conditions, such as repeated blood transfusions, chronic hemolysis, or certain genetic disorders like hemochromatosis. The presence of hemosiderin (铁蛋白) in tissues can be detected through various medical imaging techniques or biopsies. Its buildup can lead to tissue damage and organ dysfunction, particularly in the liver, heart, and pancreas. This is because excessive iron can generate free radicals, contributing to oxidative stress and cellular injury. Therefore, understanding the role of hemosiderin (铁蛋白) is essential for diagnosing and managing conditions related to iron overload. In clinical practice, doctors often monitor the levels of hemosiderin (铁蛋白) in patients who are at risk of iron overload. Treatments may involve phlebotomy, the process of removing blood from the body, or chelation therapy, which uses medications to bind excess iron and facilitate its excretion. These interventions aim to reduce the levels of hemosiderin (铁蛋白) and prevent potential complications associated with iron toxicity. Research continues to explore the implications of hemosiderin (铁蛋白) accumulation in various diseases, including its potential role in neurodegenerative disorders. Some studies suggest that increased levels of hemosiderin (铁蛋白) in the brain could be linked to conditions like Alzheimer's disease and Parkinson's disease. This highlights the importance of maintaining iron homeostasis in the body, as both iron deficiency and excess can have detrimental effects on health. In summary, hemosiderin (铁蛋白) is an important component of iron metabolism, serving as a storage form of iron in the body. While it is essential for maintaining adequate iron levels, excessive accumulation can lead to serious health issues. Understanding the balance of hemosiderin (铁蛋白) and its implications for health is crucial for effective medical management and research into iron-related disorders. As we continue to learn about the complexities of iron metabolism, the study of hemosiderin (铁蛋白) will undoubtedly remain a significant area of focus in both clinical and research settings.

铁蛋白是一种复杂的蛋白质，在人体内的铁代谢中发挥着重要作用。这种物质主要是由红血球中的血红蛋白分解而成，血红蛋白是负责运输氧气的红血球中的蛋白质。当红血球被破坏时，铁被释放并以多种形式储存，其中一种就是铁蛋白。与另一种铁储存蛋白质——铁蛋白不同，铁蛋白的溶解性较差，通常存在于铁过量的组织中。铁蛋白的积累可能由于多种情况引起，如反复输血、慢性溶血或某些遗传疾病如血色病。 通过各种医学成像技术或活检可以检测到组织中铁蛋白的存在。其积累可能导致组织损伤和器官功能障碍，特别是在肝脏、心脏和胰腺。这是因为过量的铁会产生自由基，导致氧化应激和细胞损伤。因此，理解铁蛋白的作用对于诊断和管理与铁过载相关的疾病至关重要。 在临床实践中，医生通常会监测有铁过载风险的患者体内的铁蛋白水平。治疗方法可能包括放血，即从体内去除血液，或螯合疗法，即使用药物结合过量的铁并促进其排泄。这些干预措施旨在降低铁蛋白的水平，并防止与铁毒性相关的潜在并发症。 研究继续探索铁蛋白在各种疾病中的积累影响，包括其在神经退行性疾病中的潜在作用。一些研究表明，脑内铁蛋白水平的增加可能与阿尔茨海默病和帕金森病等疾病有关。这突显了维持身体铁稳态的重要性，因为铁缺乏和过量都可能对健康产生不利影响。 总之，铁蛋白是铁代谢的重要组成部分，作为体内铁的储存形式。虽然它对于维持足够的铁水平至关重要，但过量积累可能导致严重的健康问题。理解铁蛋白的平衡及其对健康的影响对于有效的医疗管理和铁相关疾病的研究至关重要。随着我们继续了解铁代谢的复杂性，铁蛋白的研究无疑将继续成为临床和研究领域的重要关注点。