kallikrein

简明释义

英[ˌkælɪˈkriːɪn]美[ˌkælɪˈkrɪrn]

n. [生化] 激肽释放酶；血管舒缓素

英英释义

单词用法

同义词

反义词

例句

1.On the cell of expressing human tissue kallikrein for gene modification, rigid envelope material with bi-directional flowability is coated.

在基因修饰的表达人组织激肽释放酶的细胞上包覆着具有刚性和双向流通性的包膜材料；

2.The invention relates to the pharmaceutical use of human urinary kallikrein in the treatment of acute coronary artery disease and pharmaceutical composition prepared by the method.

本发明涉及人尿激肽原酶用于治疗急性冠状动脉疾病的药物用途及按该方法制备的药物组合物。

3.Therefore, it is possible that renal tissue kallikrein-bradykinin system is also released and activated by the stimulation of inflammation in sepsis.

因此，肾脏的组织型血管增渗酶也有可能被败血症引发的发炎反应刺激而释放出来，并产生作用。

4.CONCLUSION Human urinary kallikrein is effective and relatively safe in treatment of acute cerebral infarction in the vascular distribution of the internal carotid artery.

结论人尿激肽原酶治疗急性颈内动脉系统脑梗死所致的神经功能缺损，其效果及安全性良好。

5.The invention relates to the pharmaceutical use of human urinary kallikrein in the treatment of acute coronary artery disease and pharmaceutical composition prepared by the method.

本发明涉及人尿激肽原酶用于治疗急性冠状动脉疾病的药物用途及按该方法制备的药物组合物。

6.Aim: To investigate the expression of human kallikrein 15 (KLK15) in the primary epithelial ovarian carcinoma and the clinical significance.

目的：研究上皮性卵巢癌组织中人类组织激肽释放酶15 (KLK15)蛋白的表达。

7.Conclusion It is safe and effective by using urinary kallikrein on acute cerebral infarction.

结论尤瑞克林治疗急性脑梗死安全有效。

8.It was presumed that KBP may playa role in the regulation of metabolism of tissue kallikrein on the level of biosynthesis and excretion.

推测KBP可能在合成和分泌的水平上，对组织激肽释放酶的代谢及活性起调节作用。

9.The study found that elevated levels of kallikrein are associated with increased inflammation.

研究发现，升高的激肽酶水平与炎症增加相关。

10.Researchers are investigating the role of kallikrein in cardiovascular diseases.

研究人员正在调查激肽酶在心血管疾病中的作用。

11.The enzyme kallikrein plays a crucial role in blood pressure regulation.

激肽酶在血压调节中发挥着关键作用。

12.Increased activity of kallikrein may lead to enhanced pain sensitivity.

增加的激肽酶活性可能导致增强的疼痛敏感性。

13.The therapeutic potential of kallikrein inhibitors is being explored for cancer treatment.

针对癌症治疗的激肽酶抑制剂的治疗潜力正在被探索。

作文

Kallikrein is an important enzyme that plays a significant role in various physiological processes within the human body. It is primarily known for its function in the kallikrein-kinin system, which is crucial for regulating blood pressure, inflammation, and pain. The term 'kallikrein' refers to a group of serine proteases that are involved in the cleavage of kininogen, resulting in the production of kinins, which are peptide mediators that induce vasodilation and increase vascular permeability. This mechanism is vital for maintaining homeostasis and responding to injury or infection. The significance of kallikrein (激肽酶) extends beyond just the regulation of blood flow and inflammation. Research has shown that it may also play a role in various diseases, including hypertension, heart failure, and certain types of cancer. For instance, elevated levels of kallikrein (激肽酶) have been associated with increased risk of cardiovascular events, suggesting that this enzyme could be a potential biomarker for cardiovascular health. Furthermore, the modulation of kallikrein (激肽酶) activity has been explored as a therapeutic target in managing these conditions. In addition to its role in the cardiovascular system, kallikrein (激肽酶) is also involved in the regulation of kidney function. It helps to control renal blood flow and glomerular filtration rate, which are essential for proper kidney operation. Dysregulation of kallikrein (激肽酶) activity can lead to renal complications, emphasizing its importance in nephrology. Moreover, the study of kallikrein (激肽酶) is not limited to human health; it has implications in other fields such as biochemistry and pharmacology. Scientists are investigating how kallikrein (激肽酶) can be harnessed for drug development, particularly in creating new treatments for conditions characterized by inflammation and pain. Understanding the molecular mechanisms behind kallikrein (激肽酶) activity could lead to innovative therapies that improve patient outcomes. In conclusion, kallikrein (激肽酶) is a multifaceted enzyme with far-reaching implications in health and disease. Its role in the kallikrein-kinin system highlights its importance in cardiovascular health, renal function, and potential therapeutic applications. As research continues to unveil the complexities surrounding kallikrein (激肽酶), it is likely that we will discover even more about its functions and how we can leverage this knowledge for better health management. Understanding kallikrein (激肽酶) not only enhances our knowledge of human physiology but also opens new avenues for medical advancements.

激肽酶是一种重要的酶，在人体内的各种生理过程中发挥着重要作用。它主要以其在激肽-激肽系统中的功能而闻名，该系统对于调节血压、炎症和疼痛至关重要。术语“激肽酶”指的是一组丝氨酸蛋白酶，它们参与肽酶原的裂解，从而产生激肽，这些肽介质诱导血管舒张并增加血管通透性。这一机制对维持体内稳态以及对损伤或感染的反应至关重要。 激肽酶的意义不仅限于血流和炎症的调节。研究表明，它也可能在多种疾病中发挥作用，包括高血压、心力衰竭和某些类型的癌症。例如，激肽酶的水平升高与心血管事件风险增加相关，这表明这种酶可能是心血管健康的潜在生物标志物。此外，调节激肽酶活性已被探讨作为管理这些疾病的治疗靶点。 除了在心血管系统中的作用，激肽酶还参与肾功能的调节。它有助于控制肾脏血流和肾小球滤过率，这对肾脏的正常运作至关重要。激肽酶活性的失调可能导致肾脏并发症，强调了它在肾脏病学中的重要性。 此外，激肽酶的研究不仅限于人类健康；它在生物化学和药理学等其他领域也具有重要意义。科学家们正在研究如何利用激肽酶开发药物，特别是在创造针对以炎症和疼痛为特征的疾病的新疗法方面。理解激肽酶活背后的分子机制可能会导致创新疗法的出现，从而改善患者的预后。 总之，激肽酶是一种多面向的酶，对健康和疾病有着深远的影响。它在激肽-激肽系统中的作用突显了它在心血管健康、肾功能和潜在治疗应用中的重要性。随着研究不断揭示激肽酶的复杂性，我们可能会发现更多关于它的功能以及如何利用这一知识来改善健康管理的信息。理解激肽酶不仅增强了我们对人体生理学的认识，也为医学进步开辟了新的途径。