karyolysis

简明释义

英[/ˌkɛr.i.əˈlɪs.ɪs/]美[/ˌkɛr.i.əˈlɪs.ɪs/]

n. [细胞] 核溶解

英英释义

单词用法

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反义词

例句

1.Many nuclei have become pyknotic (shrunken and dark) and have then undergone karorrhexis (fragmentation) and karyolysis (dissolution). The cytoplasm and cell borders are not recognizable.

许多细胞核发生了核浓缩，接着出现核碎裂和核溶解现象。

2.Many nuclei have become pyknotic (shrunken and dark) and have then undergone karorrhexis (fragmentation) and karyolysis (dissolution). The cytoplasm and cell borders are not recognizable.

许多细胞核发生了核浓缩，接着出现核碎裂和核溶解现象。

3.Results the Nissl bodies in the spinal cord and the DRG neurons were observed to have pyknosis, accompanied by collapse and karyolysis of Nissl body.

结果D组脊髓和DRG神经元的尼氏体体积减小，并且有尼氏体的脱失和溶解。

4.Severe nuclear damage indicated by pyknosis and karyolysis are customarily taken as evidence of cell necrosis.

表现为核浓缩和核溶解的严重核损伤通常被认为是细胞坏死的证据。

5.During the examination of the tissue sample, the pathologist noted significant karyolysis, indicating cell death.

在组织样本的检查中，病理学家注意到显著的核溶解，这表明细胞死亡。

6.The presence of karyolysis in the biopsy results suggested a severe inflammatory response.

活检结果中出现的核溶解提示了严重的炎症反应。

7.Researchers observed karyolysis in the cancer cells after treatment with chemotherapy drugs.

研究人员在化疗药物治疗后观察到癌细胞中的核溶解现象。

8.The histological analysis revealed areas of karyolysis that were indicative of necrosis.

组织学分析显示出核溶解区域，这表明坏死的存在。

9.In the context of cell injury, karyolysis is a critical marker for understanding the extent of damage.

在细胞损伤的背景下，核溶解是理解损伤程度的关键标志。

作文

In the study of cell biology, understanding the processes that occur within a cell is crucial for comprehending how life functions at a microscopic level. One such process is karyolysis, which refers to the dissolution of the cell nucleus. This phenomenon occurs during certain types of cell death, particularly in necrosis, where the integrity of the cell is compromised. When a cell undergoes karyolysis (核溶解), the nuclear material begins to break down, leading to the eventual loss of the nucleus itself. This process is often accompanied by other cellular changes, such as cytoplasmic swelling and the breakdown of cellular structures. Understanding karyolysis is essential for researchers studying diseases where cell death plays a significant role, such as cancer and neurodegenerative disorders. In these conditions, the regulation of cell death pathways is crucial, and karyolysis can serve as a marker for pathological changes within tissues. For instance, in a tumor environment, the presence of karyolysis may indicate areas of necrotic tissue, suggesting that the tumor is outpacing its blood supply and leading to cell death due to lack of nutrients. Additionally, karyolysis is not just an isolated event; it often occurs alongside other forms of cell death, such as apoptosis and autophagy. While apoptosis is a programmed and controlled form of cell death beneficial for maintaining homeostasis, karyolysis typically signals a more chaotic and uncontrolled demise. This distinction is vital for medical professionals when diagnosing and treating various conditions. Moreover, the study of karyolysis has implications for regenerative medicine and therapeutic interventions. By understanding the triggers and consequences of karyolysis (核溶解), scientists can develop strategies to protect healthy cells from undergoing this process in disease states or to promote karyolysis in targeted cancer therapies to eliminate malignant cells. In conclusion, karyolysis is a fundamental concept in cell biology that highlights the complex nature of cell death and its implications for health and disease. As research continues to advance, a deeper understanding of karyolysis and its associated mechanisms will undoubtedly contribute to the development of innovative treatments for various diseases, ultimately improving patient outcomes. The ongoing exploration of cellular processes such as karyolysis will remain a cornerstone of biological research, shaping our knowledge of life itself.

在细胞生物学的研究中，理解细胞内部发生的过程对于理解生命在微观层面上的功能至关重要。其中一个过程是karyolysis，指的是细胞核的溶解。这种现象发生在某些类型的细胞死亡过程中，特别是在坏死中，细胞的完整性受到损害。当细胞经历karyolysis（核溶解）时，核材料开始分解，最终导致核的丧失。这个过程通常伴随着其他细胞变化，如细胞质肿胀和细胞结构的破坏。 理解karyolysis对研究细胞死亡在疾病中扮演重要角色的研究人员至关重要，例如癌症和神经退行性疾病。在这些情况下，细胞死亡途径的调控至关重要，而karyolysis可以作为组织病理变化的标志。例如，在肿瘤环境中，karyolysis的存在可能表明坏死组织的区域，暗示肿瘤超越了其血液供应，导致细胞因缺乏营养而死亡。 此外，karyolysis并不是一个孤立的事件；它通常与其他形式的细胞死亡一起发生，例如凋亡和自噬。虽然凋亡是一种程序化和受控的细胞死亡形式，有利于维持稳态，但karyolysis通常预示着一种更加混乱和不受控制的消亡。这一区别对于医疗专业人员在诊断和治疗各种疾病时至关重要。 此外，研究karyolysis对再生医学和治疗干预也有影响。通过理解karyolysis（核溶解）的触发因素和后果，科学家们可以开发出保护健康细胞免于在疾病状态下经历这一过程的策略，或在靶向癌症治疗中促进karyolysis以消除恶性细胞。 总之，karyolysis是细胞生物学中的一个基本概念，突显了细胞死亡的复杂性质及其对健康和疾病的影响。随着研究的不断推进，对karyolysis及其相关机制的深入理解无疑将有助于开发针对各种疾病的创新治疗方案，最终改善患者的预后。对诸如karyolysis这样的细胞过程的持续探索将始终是生物研究的基石，塑造我们对生命本身的认识。