laevorotatory

简明释义

英[ˌliːvəʊˈrəʊtətərɪ]美[ˌlivoˈrotˌtɔri]

左旋物

左旋的

英英释义

单词用法

同义词

反义词

例句

1.According the laevorotatory helicoid structure characteristic of the stainless steel spiral plate, analyzed the forming process, and introduced forming die structure.

针对不锈钢螺旋板的左旋螺旋面结构特点，分析了成形工艺，并介绍了成形模具结构。

2.According the laevorotatory helicoid structure characteristic of the stainless steel spiral plate, analyzed the forming process, and introduced forming die structure.

针对不锈钢螺旋板的左旋螺旋面结构特点，分析了成形工艺，并介绍了成形模具结构。

3.The compound was found to be laevorotatory, indicating it rotates plane-polarized light to the left.

该化合物被发现是左旋的，这表明它将平面偏振光向左旋转。

4.In organic chemistry, laevorotatory substances are often contrasted with their dextrorotatory counterparts.

在有机化学中，左旋物质通常与其右旋对应物进行对比。

5.The laevorotatory nature of the molecule was confirmed through optical rotation measurements.

通过光学旋转测量确认了该分子的左旋性质。

6.Pharmaceuticals can exhibit laevorotatory activity, which is crucial for their efficacy.

药物可能表现出左旋活性，这对其疗效至关重要。

7.The laevorotatory isomer of the drug showed significantly different effects compared to the dextrorotatory form.

该药物的左旋异构体与右旋形式相比显示出显著不同的效果。

作文

In the realm of chemistry, the concept of chirality plays a crucial role in understanding the behavior of molecules. One fascinating aspect of chirality is the property of optical activity, which refers to the ability of a substance to rotate the plane of polarized light. This rotation can occur in two directions: clockwise and counterclockwise. The terms used to describe these two types of rotation are dextrorotatory and laevorotatory. While dextrorotatory substances rotate light to the right, laevorotatory substances rotate light to the left. This distinction is not merely academic; it has significant implications in various fields, including pharmaceuticals, where the efficacy of a drug can depend on its chirality. To better understand laevorotatory compounds, we can consider the example of certain amino acids. Amino acids are the building blocks of proteins and exist in two enantiomeric forms: L (levo) and D (dextro). The L form of amino acids, such as L-alanine, is classified as laevorotatory, as it rotates polarized light to the left. In contrast, the D form is dextrorotatory, rotating light to the right. This difference in optical activity is not just a matter of nomenclature; it can influence how these amino acids interact with biological systems. For instance, our bodies predominantly utilize L-amino acids for protein synthesis, while D-amino acids are often found in certain bacterial cell walls. The significance of laevorotatory substances extends beyond amino acids. Many natural products, including sugars and alkaloids, exhibit chirality and possess either dextrorotatory or laevorotatory properties. For example, the sugar glucose is laevorotatory, whereas fructose is dextrorotatory. This difference is critical in biochemistry, as enzymes that catalyze reactions involving these sugars are often specific to one enantiomer. The ability of an enzyme to recognize and interact with a particular chiral molecule can determine the course of metabolic pathways, affecting everything from energy production to the synthesis of vital biomolecules. Furthermore, the pharmaceutical industry is acutely aware of the importance of chirality. Many drugs are chiral, and their therapeutic effects can vary drastically between enantiomers. A well-known example is the drug thalidomide, which was prescribed in the late 1950s and early 1960s. One enantiomer of thalidomide was effective in treating morning sickness in pregnant women, while the other caused severe birth defects. This tragedy highlighted the need for rigorous testing of chiral drugs, leading to stricter regulations regarding the use of laevorotatory and dextrorotatory forms in medical treatments. In conclusion, the concept of laevorotatory is integral to the study of chirality and optical activity in chemistry. Understanding the properties of laevorotatory compounds and their interactions with biological systems is essential for advancing fields such as biochemistry and pharmacology. As we continue to explore the intricate world of chiral molecules, the implications of laevorotatory and dextrorotatory substances will undoubtedly shape future discoveries and innovations in science and medicine.

在化学领域，手性这一概念对于理解分子的行为至关重要。手性的一个迷人方面是光学活性的特性，这指的是物质旋转偏振光平面的能力。这种旋转可以朝两个方向进行：顺时针和逆时针。用于描述这两种旋转的术语是右旋和左旋。右旋物质将光向右旋转，而左旋物质则向左旋转。这一区别不仅仅是学术上的，它在包括制药在内的多个领域具有重要意义，因为药物的效力可能依赖于其手性。 为了更好地理解左旋化合物，我们可以考虑某些氨基酸的例子。氨基酸是蛋白质的基本组成部分，并以两种对映体形式存在：L（左旋）和D（右旋）。L型氨基酸，例如L-丙氨酸，被归类为左旋，因为它将偏振光向左旋转。相反，D型则是右旋，向右旋转光。这种光学活性的差异不仅仅是命名问题；它会影响这些氨基酸与生物系统的相互作用。例如，我们的身体主要利用L型氨基酸进行蛋白质合成，而D型氨基酸通常存在于某些细菌的细胞壁中。 左旋物质的重要性超越了氨基酸。许多天然产物，包括糖和生物碱，表现出手性并具有右旋或左旋特性。例如，糖类葡萄糖是左旋的，而果糖是右旋的。这种差异在生物化学中至关重要，因为催化涉及这些糖的反应的酶通常对一种对映体特异。酶识别并与特定手性分子相互作用的能力可以决定代谢途径的进程，影响从能量生产到重要生物分子合成的一切。 此外，制药行业对手性的重要性高度敏感。许多药物是手性的，其治疗效果在对映体之间可能有显著差异。一个众所周知的例子是沙利度胺，这种药物在20世纪50年代和60年代初被开处方。沙利度胺的一个对映体在治疗孕妇晨吐方面有效，而另一个则导致严重的出生缺陷。这场悲剧突显了对手性药物进行严格测试的必要性，导致对使用左旋和右旋形式的医疗治疗实施更严格的规定。 总之，左旋概念是研究化学中手性和光学活性的核心。理解左旋化合物及其与生物系统相互作用的特性对于推动生物化学和药理学等领域至关重要。随着我们继续探索复杂的手性分子世界，左旋和右旋物质的影响无疑将塑造科学和医学未来的发现与创新。