levodopa

简明释义

英[ˌliːvə(ʊ)ˈdəʊpə]美[ˌlivəˈdopə]

n. [药]左旋多巴（等于 L-dopa）

英英释义

单词用法

同义词

反义词

例句

1.Objective To observe the effects of levodopa on strabismic amblyopia model eyes in cats, and explore amblyopia pathogenesis.

目的观察左旋多巴对猫弱视眼模型的作用，以探讨弱视的发病机理。

2.Low dose levodopa and dopamine agonists are effective in controlling most symptoms of the disorder.

小剂量左旋多巴和多巴胺激动剂治疗有效。

3.Results: We identified 126 incident Parkinson disease patients treated with levodopa for at least 2 months.

结果：研究确诊了126例左旋多巴治疗至少2个月的偶发帕金森病患者。

4.Aim: to study the efficacy and safety of entacapone as an adjunct to levodopa treatment in parkinsonian patients with wearing-off motor fluctuations.

目的：探讨添加恩他卡朋治疗帕金森病患者剂末现象的疗效及安全性。

5.Objective To explore the clinical curative effect of children's amblyopia treated with levodopa and carbidopa.

目的探讨左旋多巴和卡比·多巴治疗儿童弱视的临床疗效。

6.Although levodopa helps deal with the signs of the disease.

虽然左旋多巴帮助解决该疾病的症状。

7.Second, levodopa therapy is not associated with neurotoxicity.

第二，左旋多巴治疗和神经毒性并不相关。

8.Objective: To establish the preparation method of levodopa analog (abbreviate: LDA) reference substance by AKTA Explorer 100 Preparative Chromatography System;

目的：建立制备色谱层析系统制备左旋多巴类似物（简称：LDA）对照品的方法；

9.Objective To investigate and research the application of insulin and levodopa in growth hormone releasing test .

目的探讨胰岛素、左旋多巴在生长激素激发试验中的应用。

10.Doctors often prescribe levodopa to help manage the symptoms of Parkinson's disease.

医生常常开处方左旋多巴来帮助控制帕金森病的症状。

11.Patients taking levodopa may experience fluctuations in their symptoms throughout the day.

服用左旋多巴的患者可能会在一天中经历症状波动。

12.The effectiveness of levodopa can diminish over time, requiring adjustments in dosage.

左旋多巴的有效性可能会随着时间的推移而减弱，需要调整剂量。

13.Some side effects of levodopa include nausea and dizziness.

左旋多巴的一些副作用包括恶心和头晕。

14.Combining levodopa with other medications can enhance its therapeutic effects.

将左旋多巴与其他药物结合使用可以增强其治疗效果。

作文

Levodopa, often referred to in the medical community as a crucial medication for treating Parkinson's disease, plays a significant role in improving the quality of life for those affected by this neurodegenerative disorder. Parkinson's disease is characterized by the loss of dopamine-producing neurons in the brain, leading to motor symptoms such as tremors, rigidity, and bradykinesia. The introduction of levodopa into treatment regimens has revolutionized the management of these symptoms. 左旋多巴, the Chinese term for levodopa, is a precursor to dopamine, which means that once ingested, it is converted into dopamine in the brain, effectively replenishing the dwindling supply of this essential neurotransmitter. The mechanism of action of levodopa is fascinating. When patients take levodopa, it crosses the blood-brain barrier and is transformed into dopamine, which helps to alleviate the motor deficits associated with Parkinson's disease. This transformation is vital because the brain's ability to produce dopamine diminishes as the disease progresses. As a result, levodopa not only helps improve movement but also enhances overall vitality, allowing patients to engage more fully in daily activities. However, the use of levodopa is not without its challenges. Over time, many patients experience fluctuations in their response to the medication, a phenomenon known as 'wearing-off.' This means that the effects of levodopa may diminish before the next dose is due, leading to a return of symptoms. Additionally, prolonged use can lead to involuntary movements known as dyskinesias, which can be distressing for patients. Therefore, healthcare providers must carefully manage levodopa therapy, often combining it with other medications to optimize its effects and minimize side effects. In recent years, researchers have been exploring new formulations of levodopa to address these issues. For instance, extended-release formulations aim to provide a more consistent level of the drug in the bloodstream, potentially reducing the wearing-off effect. Furthermore, adjunct therapies, such as dopamine agonists or MAO-B inhibitors, are being studied to enhance the therapeutic benefits of levodopa while mitigating its side effects. Patient education is also a critical component of levodopa therapy. Understanding how to take the medication correctly, recognizing the signs of wearing-off, and knowing when to seek medical advice can empower patients and improve their treatment outcomes. Support groups and educational resources can play a pivotal role in helping patients navigate the complexities of living with Parkinson's disease while on levodopa. In conclusion, levodopa remains a cornerstone in the treatment of Parkinson's disease, providing significant relief from debilitating symptoms. As research continues to evolve, the hope is that more effective and tailored treatments will emerge, enhancing the lives of those affected by this challenging condition. The journey with levodopa is one of both hope and complexity, requiring ongoing adaptation and support to ensure the best possible outcomes for patients. By understanding the importance of levodopa and its role in managing Parkinson's disease, we can continue to advocate for better treatment options and quality of life for individuals living with this condition.

左旋多巴，通常在医学界被称为治疗帕金森病的重要药物，在改善受这种神经退行性疾病影响的患者生活质量方面发挥着重要作用。帕金森病的特征是大脑中产生多巴胺的神经元的丧失，导致颤抖、僵硬和运动迟缓等运动症状。左旋多巴的引入彻底改变了这些症状的管理。左旋多巴是多巴胺的前体，这意味着一旦摄入，它会在大脑中转化为多巴胺，有效地补充这种必需神经递质的减少供应。 左旋多巴的作用机制非常有趣。当患者服用左旋多巴时，它穿过血脑屏障并转化为多巴胺，有助于缓解与帕金森病相关的运动缺陷。这种转化至关重要，因为随着疾病的发展，大脑产生多巴胺的能力会减弱。因此，左旋多巴不仅有助于改善运动，还能增强整体活力，使患者能够更充分地参与日常活动。 然而，使用左旋多巴并非没有挑战。随着时间的推移，许多患者会经历对药物反应的波动现象，称为“穿戴效应”。这意味着左旋多巴的效果可能在下一剂到期之前减弱，导致症状的复发。此外，长期使用可能导致不自主运动，称为运动障碍，这对患者来说可能是令人痛苦的。因此，医疗提供者必须仔细管理左旋多巴治疗，通常将其与其他药物结合使用，以优化其效果并最小化副作用。 近年来，研究人员一直在探索新的左旋多巴制剂，以解决这些问题。例如，延长释放制剂旨在提供血液中药物水平的更一致，可能减少穿戴效应。此外，辅助疗法，如多巴胺激动剂或MAO-B抑制剂，正在研究中，以增强左旋多巴的治疗益处，同时减轻其副作用。 患者教育也是左旋多巴治疗的重要组成部分。了解如何正确服用药物，识别穿戴效应的迹象，以及知道何时寻求医疗建议，可以增强患者的能力并改善治疗结果。支持小组和教育资源可以在帮助患者应对与帕金森病相关的复杂性方面发挥关键作用，同时使用左旋多巴。 总之，左旋多巴仍然是帕金森病治疗的基石，为缓解令人痛苦的症状提供了显著的缓解。随着研究的不断发展，希望能出现更有效和量身定制的治疗方案，提高受此挑战性疾病影响的人的生活。与左旋多巴的旅程既充满希望又复杂，需要持续适应和支持，以确保患者获得最佳的治疗结果。通过理解左旋多巴的重要性及其在管理帕金森病中的作用，我们可以继续倡导更好的治疗选择和生活质量，以改善生活在这种疾病中的个体。