lipophilic

简明释义

英[ˌlɪpəʊˈfɪlɪk]美[ˌlɪpəˈfɪlɪk]

adj. 亲脂性的，亲脂的

英英释义

单词用法

同义词

反义词

例句

1.Conclusions Lauroyl indapamide is a weak acid with lipophilic property.

结论月桂酰吲达帕胺为弱酸性亲脂性药物。

2.Pinenut milk HLB value is about 6 that is lower than ordinary plant protein beverage. So it need the emulsify stabilizer that the lipophilic group is more.

HLB值是选择乳化稳定剂的重要指标，松仁乳的HLB值在6左右，较一般的植物蛋白饮料的HLB值低，需要亲油基较多的乳化稳定剂。

3.This may also be an important issue when you start certain medications, like lipophilic drugs-for example, sedation medications or hydrophilic drugs.

这也可能是一个重要的问题，当你开始服用某些药物，像亲脂性药物，例如，镇静药物或亲水性药物。

4.Poison dart frogs secrete lipophilic alkaloid toxins through their skin.

毒镖蛙在身体皮肤下隐藏着亲脂性的碱性毒液。

5.The fulvic acid or humic acid is the body, in which some proper lipophilic group or hydrophilic group has been inducted, of the series of humate surfactants .

该系列表面活性剂是以黄腐植酸盐或黑腐植酸盐为主体，在主体分子结构中引入了适当亲油基或亲水基而制成的。

6.Oil absorbent sheets are produced by lipophilic superfine fibers of non-woven clothing, able to absorb several times of the weight of the oil stains than themselves.

吸油棉系列series of oil absor bentsheets吸油索采用亲油性之超细纤维不织布制作，能迅速吸收本身重量数十倍的油污。

7.The results showed that: After the protein in shrimp head was hydrolyzed by proteinase and separated, 94.81% lipophilic compounds was extracted out by direct extraction methods.

结果表明：利用蛋白酶将虾头中的蛋白质水解分离出去，采用直接浸提法可以将虾头中94.81%的脂溶性成分提取出来；

8.Many poison dart frogs secrete lipophilic alkaloid toxins through their skin.

许多毒镖蛙会将其毒素隐藏在皮肤中。

9.OBJECTIVE To enhance the transdermal delivery of lipophilic drugs through the local hydrophilic transport regions (LTRs) formed during electroporation by applying surfactant.

目的利用表面活性剂的促渗作用，提高脂溶性药物通过电致孔形成的水性通道的经皮渗透量。

10.Certain drugs are designed to be lipophilic 亲脂性的 to enhance their absorption in fatty tissues.

某些药物被设计为<施>亲脂性的以增强它们在脂肪组织中的吸收。

11.The lipophilic 亲脂性的 nature of the compound allows it to easily penetrate cell membranes.

该化合物的<施>亲脂性的特性使其能够轻松穿透细胞膜。

12.In the study, they found that lipophilic 亲脂性的 substances accumulated in the liver more than hydrophilic ones.

在研究中，他们发现<施>亲脂性的物质在肝脏中的积累比亲水性物质多。

13.The formulation contains both lipophilic 亲脂性的 and hydrophilic components to improve solubility.

该配方包含<施>亲脂性的和亲水性成分，以改善溶解度。

14.Surfactants often have a lipophilic 亲脂性的 tail that helps reduce surface tension in liquids.

表面活性剂通常具有<施>亲脂性的尾部，有助于降低液体的表面张力。

作文

In the field of chemistry and biology, understanding the properties of different compounds is crucial for various applications, including drug development and environmental science. One term that often arises in these discussions is lipophilic, which refers to the affinity of a substance for lipids or fats. Substances that are lipophilic tend to dissolve well in non-polar solvents, such as oils, rather than in water. This characteristic plays a significant role in how drugs are absorbed, distributed, and metabolized in the body. For instance, many pharmaceutical compounds are designed to be lipophilic to ensure they can easily cross cell membranes, which are primarily composed of lipid bilayers. When a drug is lipophilic, it can pass through these membranes more readily, allowing it to reach its target site within the body efficiently. This is particularly important for medications that need to act quickly, as their ability to penetrate cellular barriers directly influences their therapeutic effectiveness. Moreover, lipophilic compounds often exhibit prolonged retention in the body due to their tendency to accumulate in fatty tissues. This property can be advantageous for certain medications that require sustained release over time. However, it can also pose challenges, as it may lead to toxicity if the compounds accumulate excessively. Therefore, understanding the lipophilic nature of a drug is essential for determining appropriate dosing regimens and minimizing adverse effects. Beyond pharmacology, the concept of lipophilic substances extends to environmental science. Many pollutants, such as persistent organic pollutants (POPs), are lipophilic, which means they can accumulate in the fatty tissues of living organisms. This bioaccumulation can have detrimental effects on wildlife and human health, as these compounds may become concentrated in the food chain. For example, fish that inhabit contaminated waters can accumulate lipophilic toxins, which then pose risks to predators, including humans, who consume them. Understanding the lipophilic properties of these pollutants is vital for assessing environmental risks and developing strategies for remediation. Furthermore, the study of lipophilic compounds has led to advancements in various fields, such as nanotechnology and material science. Researchers are exploring ways to manipulate lipophilic materials to create innovative delivery systems for drugs or improve the performance of certain products. For instance, lipophilic nanoparticles can be engineered to encapsulate hydrophilic drugs, enhancing their solubility and bioavailability. This approach can significantly improve the effectiveness of treatments for various diseases, including cancer and chronic conditions. In conclusion, the term lipophilic describes a fundamental property of substances that have a strong affinity for lipids and fats. Its implications span multiple disciplines, from medicine to environmental science, highlighting the importance of understanding how lipophilic characteristics influence the behavior of compounds in biological and ecological systems. As research continues to advance, the knowledge surrounding lipophilic substances will undoubtedly lead to further innovations and solutions to pressing global challenges.

在化学和生物学领域，理解不同化合物的性质对于药物开发和环境科学等各种应用至关重要。在这些讨论中，一个经常出现的术语是lipophilic，它指的是物质对脂质或脂肪的亲和力。lipophilic物质往往容易溶解在非极性溶剂中，例如油，而不是水。这一特性在药物的吸收、分布和代谢过程中起着重要作用。 例如，许多药物化合物被设计为lipophilic，以确保它们可以轻松穿过细胞膜，而细胞膜主要由脂质双层组成。当药物具有lipophilic特性时，它可以更容易地穿过这些膜，从而有效地到达体内的目标部位。这对于需要快速起效的药物尤为重要，因为它们穿透细胞屏障的能力直接影响其治疗效果。 此外，由于lipophilic化合物倾向于在体内的脂肪组织中积累，因此它们通常在体内的滞留时间较长。这一特性对于某些需要持续释放的药物来说是有利的。然而，这也可能带来挑战，因为如果化合物过度积累，可能会导致毒性。因此，理解药物的lipophilic特性对于确定适当的给药方案和最小化不良反应至关重要。 除了药理学，lipophilic物质的概念还扩展到环境科学。许多污染物，例如持久性有机污染物（POPs），都是lipophilic的，这意味着它们可以在生物体的脂肪组织中积累。这种生物积累可能对野生动物和人类健康产生不利影响，因为这些化合物可能在食物链中变得浓缩。例如，栖息在受污染水域的鱼类可以积累lipophilic毒素，而这些毒素则对捕食者，包括人类，构成风险。因此，理解这些污染物的lipophilic特性对于评估环境风险和制定修复策略至关重要。 此外，lipophilic化合物的研究推动了纳米技术和材料科学等多个领域的发展。研究人员正在探索操纵lipophilic材料的方法，以创建创新的药物递送系统或改善某些产品的性能。例如，lipophilic纳米颗粒可以被设计用于包裹亲水性药物，从而增强其溶解度和生物利用度。这种方法可以显著提高针对各种疾病（包括癌症和慢性病）的治疗效果。 总之，术语lipophilic描述了一种基本性质，即物质对脂质和脂肪具有强烈的亲和力。其影响跨越多个学科，从医学到环境科学，突显了理解lipophilic特性如何影响化合物在生物和生态系统中行为的重要性。随着研究的不断推进，围绕lipophilic物质的知识无疑将导致进一步的创新和解决全球紧迫挑战的方案。