liposomes

简明释义

英[ˈlaɪpəˌsoʊmz]美[ˈlaɪpəˌsoʊmz]

n. [生化]脂质体（liposome 的复数形式）；微脂囊

英英释义

单词用法

同义词

反义词

例句

1.CONCL_ USION: The established method is simple and accurate, which can be used for quality control of matrine liposomes.

结论：本方法操作简便、准确，可用于苦参碱脂质体的质量控制。

2.One example is that lipids spontaneously form liposomes, the hollow bilayered vesicles that must have yielded the cell membrane.

一个例子是脂质自发形成脂质体，这种中空双层囊泡必须让出细胞膜。

3.Seed Oil, Dead Sea Mineral Water, Olive Oil, Evening Primrose Oil, Liposomes (Phospholipids).

琉璃苣菜籽油，死海矿物水，橄榄油，晚樱草油，脂质体(磷脂)。

4.Objective To investigate the preparation method and the transdermal diffusion of flurbiprofen liposomes.

目的研究氟比洛芬脂质体的制备和体外透皮扩散。

5.OBJECTIVE: To optimize the prescription and preparation of matrine liposomes.

目的：筛选苦参碱脂质体的最优处方和最佳制备工艺。

6.OBJECTIVE: To prepare the liposomes carrier materials lecithin.

目的：制备脂质体载体材料卵磷脂。

7.One example is that lipids spontaneously form liposomes, the hollow bilayered vesicles that must have yielded the cell membrane.

一个例子是脂质自发形成脂质体，这种中空双层囊泡必须让出细胞膜。

8.The coupling condition of different lipid ratio, glutaraldehyde concentration and types of liposomes was probed.

探索了不同比例的脂、不同戊二醛浓度和不同类型脂质体的偶联情况。

9.Researchers are studying the effectiveness of liposomes 脂质体 in delivering chemotherapy drugs directly to cancer cells.

研究人员正在研究<liposomes>在将化疗药物直接送到癌细胞中的有效性。

10.The new vaccine utilizes liposomes 脂质体 to enhance immune response.

新疫苗利用<liposomes>来增强免疫反应。

11.Pharmaceutical companies are exploring liposomes 脂质体 as a means to improve drug solubility.

制药公司正在探索<liposomes>作为改善药物溶解度的一种手段。

12.In cosmetic formulations, liposomes 脂质体 are used to encapsulate active ingredients for better skin absorption.

在化妆品配方中，<liposomes>被用来封装活性成分以更好地被皮肤吸收。

13.The stability of liposomes 脂质体 can be affected by temperature and pH levels.

温度和pH值会影响<liposomes>的稳定性。

作文

Liposomes are small spherical vesicles that are composed of one or more phospholipid bilayers. They are often used in the field of drug delivery and biotechnology due to their ability to encapsulate various substances, including drugs, genes, and vaccines. The unique structure of liposomes (脂质体) allows them to protect the encapsulated materials from degradation, enhance their solubility, and facilitate their transport across biological membranes. The concept of liposomes (脂质体) was first introduced in the early 1960s by Dr. Alec D. Bangham, who discovered that when phospholipids were hydrated, they formed bilayer structures. This discovery opened up new avenues for drug delivery systems, as liposomes (脂质体) can be engineered to improve the pharmacokinetics of therapeutic agents. For example, by altering the composition of the lipid bilayer, researchers can control the release rate of the drug, target specific tissues, and minimize side effects. One of the key advantages of using liposomes (脂质体) in medicine is their biocompatibility and biodegradability. Since they are made from natural phospholipids, they are generally well-tolerated by the human body. This characteristic is particularly important in the development of drug formulations for cancer therapy, where minimizing toxicity to healthy cells is crucial. By encapsulating chemotherapeutic agents within liposomes (脂质体), researchers have been able to create targeted therapies that deliver drugs directly to tumor cells while sparing normal tissues. In addition to drug delivery, liposomes (脂质体) also have applications in vaccine development. They can serve as adjuvants, which are substances that enhance the immune response to vaccines. By incorporating antigens into liposomes (脂质体), researchers can improve the stability and efficacy of vaccines, leading to stronger and longer-lasting immunity. This has been particularly beneficial in the development of vaccines against infectious diseases, such as influenza and COVID-19. Despite their many advantages, there are challenges associated with the use of liposomes (脂质体). One major concern is the stability of liposomes (脂质体) during storage and administration. Factors such as temperature, pH, and ionic strength can affect the integrity of the lipid bilayer, potentially leading to premature release of the encapsulated material. To address this issue, researchers are continuously working on optimizing the formulation and manufacturing processes of liposomes (脂质体). Moreover, while liposomes (脂质体) have shown great promise in preclinical studies, translating these findings into clinical practice can be challenging. Regulatory hurdles, production scalability, and cost-effectiveness are all factors that need to be considered when developing liposomes (脂质体) for therapeutic use. In conclusion, liposomes (脂质体) are a versatile and valuable tool in modern medicine, particularly in the fields of drug delivery and vaccine development. Their unique properties enable the effective encapsulation and targeted delivery of therapeutic agents, making them an attractive option for improving patient outcomes. As research continues to advance our understanding of liposomes (脂质体), we can expect to see even more innovative applications in the future, ultimately benefiting patients around the world.

脂质体是由一个或多个磷脂双层组成的小球形囊泡。由于它们能够包裹各种物质，包括药物、基因和疫苗，因此在药物传递和生物技术领域得到了广泛应用。脂质体（liposomes）的独特结构使它们能够保护被包裹材料免受降解，增强其溶解度，并促进其穿越生物膜的运输。 脂质体（liposomes）的概念最早是在20世纪60年代初由阿列克·D·班厄姆博士提出的，他发现当磷脂被水合时，会形成双层结构。这一发现为药物传递系统开辟了新的途径，因为脂质体（liposomes）可以被设计来改善治疗剂的药代动力学。例如，通过改变脂质双层的组成，研究人员可以控制药物的释放速率、靶向特定组织，并最小化副作用。 使用脂质体（liposomes）在医学中的一个主要优点是它们的生物相容性和生物降解性。由于它们是由天然磷脂制成的，通常对人体良好耐受。这一特性在癌症治疗的药物配方开发中尤为重要，因为最小化对健康细胞的毒性至关重要。通过将化疗药物包裹在脂质体（liposomes）中，研究人员能够创造出直接将药物输送到肿瘤细胞的靶向疗法，同时保护正常组织。 除了药物传递，脂质体（liposomes）在疫苗开发中也有应用。它们可以作为佐剂，即增强疫苗免疫反应的物质。通过将抗原纳入脂质体（liposomes），研究人员可以提高疫苗的稳定性和有效性，从而导致更强和更持久的免疫力。这在开发针对感染性疾病的疫苗（如流感和COVID-19）方面特别有益。 尽管有许多优点，使用脂质体（liposomes）仍面临挑战。一个主要问题是脂质体（liposomes）在储存和给药过程中的稳定性。温度、pH值和离子强度等因素都可能影响脂质双层的完整性，可能导致被包裹材料的提前释放。为了解决这个问题，研究人员正在不断优化脂质体（liposomes）的配方和制造工艺。 此外，虽然脂质体（liposomes）在临床前研究中表现出巨大的潜力，但将这些发现转化为临床实践可能面临挑战。监管障碍、生产可扩展性和成本效益都是在开发用于治疗的脂质体（liposomes）时需要考虑的因素。 总之，脂质体（liposomes）是现代医学中一种多功能且有价值的工具，特别是在药物传递和疫苗开发领域。它们的独特性质使得有效包裹和靶向输送治疗剂成为可能，使其成为改善患者结果的有吸引力的选择。随着研究的不断推进，我们可以期待看到脂质体（liposomes）在未来的创新应用，最终使世界各地的患者受益。