neurotrophic

简明释义

英[ˌnjʊərəˈtrɒfɪk]美[njʊəroʊˈtrɑːfɪk]

adj. 神经营养的；亲神经的；向神经的

英英释义

单词用法

同义词

反义词

例句

1.Yet, the neurotrophic activity of the denervated muscle results from not only NGF, but also the integration of multiple neurotrophic factors.

失神经支配肌肉的神经营养活性是各种营养因子的共同作用结果，不能用单一某种神经营养因子来代表。

2.Objective to discuss the effect of ciliary neurotrophic factors (CNTF) on behavior and hippocampus neuron of stress rats.

目的探讨睫状神经营养因子(CNTF)对应激大鼠行为和海马神经元的影响。

3.Objective to observe the expression of Schwann cell derived neurotrophic factor (SDNF) in developing lumber spinal cord of rats.

目的观察雪旺细胞源神经营养因子在大鼠生长发育腰髓中的表达。

4.Objective to develop the methods and standard for quality control of recombinant human ciliary neurotrophic factor.

目的建立重组人睫神经营养因子的质控方法和质量标准。

5.But when they were given a drug called brain-derived neurotrophic factor or BDNF they lost their fear.

但是当给他们使用一种含有脑源性神经营养因子的药物后，恐惧消失了。

6.AIM to observe the effects of glial-derived neurotrophic factors on survival and differentiation of neural precursor cells and its cooperative factors.

目的：观察胶质源性神经营养因子在神经前体细胞的存活和分化过程中的作用及其协同因子。

7.Researchers are studying the effects of neurotrophic 神经营养的 factors on nerve regeneration.

研究人员正在研究神经营养的因子对神经再生的影响。

8.The neurotrophic 神经营养的 support provided by certain proteins is crucial for neuron survival.

某些蛋白质提供的神经营养的支持对于神经元的存活至关重要。

9.Therapies that enhance neurotrophic 神经营养的 factors may help in treating neurodegenerative diseases.

增强神经营养的因子的疗法可能有助于治疗神经退行性疾病。

10.The discovery of new neurotrophic 神经营养的 agents could lead to breakthroughs in brain injury recovery.

新神经营养的因子的发现可能会导致脑损伤恢复的突破。

11.Scientists are investigating how neurotrophic 神经营养的 signals influence synaptic plasticity.

科学家正在研究神经营养的信号如何影响突触可塑性。

作文

The human nervous system is a complex network that requires constant support and nourishment to function effectively. One of the key aspects of maintaining the health and functionality of neurons is the role of neurotrophic factors. The term neurotrophic refers to substances that promote the growth, survival, and differentiation of neurons. These factors are crucial for the development of the nervous system and play significant roles in neuroplasticity, which is the ability of the brain to reorganize itself by forming new neural connections throughout life. Neurotrophic factors, such as nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF), are essential for the maintenance of neuronal health. They help neurons to survive during periods of stress and injury, ensuring that the nervous system can recover from damage. For instance, when a nerve is injured, neurotrophic factors are released to support the regeneration of the affected neurons, guiding them back to their original target cells. The importance of neurotrophic factors extends beyond just survival and repair; they also influence the functional capabilities of neurons. Studies have shown that BDNF, a prominent neurotrophic factor, is involved in learning and memory processes. This is because BDNF enhances synaptic plasticity, the mechanism through which synapses strengthen or weaken over time, in response to increases or decreases in their activity. Therefore, adequate levels of neurotrophic factors are necessary not only for basic neuronal health but also for higher cognitive functions. Moreover, research has indicated that deficits in neurotrophic factors may be linked to various neurological disorders. Conditions such as Alzheimer's disease, Parkinson's disease, and depression have been associated with altered levels of neurotrophic factors. For example, decreased BDNF levels have been observed in patients with major depressive disorder, suggesting that enhancing BDNF signaling could be a potential therapeutic strategy for treating depression. In addition to their roles in health and disease, neurotrophic factors have garnered interest in the field of regenerative medicine. Scientists are exploring ways to harness these factors to promote nerve regeneration after injuries or in degenerative diseases. By understanding how to manipulate neurotrophic signaling pathways, researchers hope to develop treatments that can restore lost functions and improve the quality of life for individuals with neurological impairments. In conclusion, the concept of neurotrophic factors encompasses a wide range of biological processes that are vital for the growth, survival, and function of neurons. Their significance in both maintaining neuronal health and facilitating cognitive processes highlights the intricate relationship between our nervous system and overall well-being. As research continues to uncover the complexities of neurotrophic signaling, it opens up new avenues for therapeutic interventions in neurological diseases and injuries, ultimately paving the way for innovative treatments that could enhance neuronal repair and cognitive function.

人类神经系统是一个复杂的网络，需要不断的支持和营养才能有效地运作。维持神经元健康和功能的关键方面之一是神经营养因子的作用。术语neurotrophic指的是促进神经元生长、生存和分化的物质。这些因子对神经系统的发展至关重要，并在神经可塑性中发挥重要作用，神经可塑性是大脑通过形成新的神经连接在一生中重新组织自己的能力。 神经营养因子，如神经生长因子（NGF）和脑源性神经营养因子（BDNF），对神经元健康的维持至关重要。它们帮助神经元在压力和损伤期间生存，确保神经系统能够从损伤中恢复。例如，当神经受伤时，会释放neurotrophic因子以支持受影响神经元的再生，引导它们回到原来的目标细胞。 neurotrophic因子的意义不仅限于生存和修复；它们还影响神经元的功能能力。研究表明，BDNF作为一种突出的neurotrophic因子，参与学习和记忆过程。这是因为BDNF增强了突触可塑性，即突触在活动增加或减少时加强或削弱的机制。因此，充足的neurotrophic因子水平不仅对基本神经元健康是必要的，也是高级认知功能所必需的。 此外，研究表明，neurotrophic因子的缺乏可能与各种神经疾病有关。阿尔茨海默病、帕金森病和抑郁症等疾病都与neurotrophic因子的水平改变有关。例如，在重度抑郁障碍患者中观察到BDNF水平降低，这表明增强BDNF信号传导可能成为治疗抑郁症的潜在策略。 除了在健康和疾病中的作用外，neurotrophic因子在再生医学领域也引起了兴趣。科学家们正在探索利用这些因子促进神经再生的方法，以应对损伤或退行性疾病。通过了解如何操控neurotrophic信号通路，研究人员希望开发出可以恢复失去功能并改善神经功能障碍者生活质量的治疗方法。 总之，neurotrophic因子的概念涵盖了一系列对神经元的生长、生存和功能至关重要的生物过程。它们在维持神经元健康和促进认知过程中的重要性突显了我们的神经系统与整体健康之间的复杂关系。随着研究不断揭示neurotrophic信号的复杂性，它为神经疾病和损伤的治疗干预开辟了新的途径，最终为创新治疗提供了可能，以增强神经修复和认知功能。