nicotinic
简明释义
adj. 烟碱的;烟碱酸的
英英释义
Relating to or denoting a type of acetylcholine receptor that responds to the neurotransmitter acetylcholine and nicotine. | 与一种对神经递质乙酰胆碱和尼古丁产生反应的乙酰胆碱受体类型相关或指代的。 |
单词用法
[生化]烟酸;尼克酸;烟碱酸 |
同义词
乙酰胆碱受体 | Nicotinic acetylcholine receptors are crucial for muscle contraction. | 烟碱型乙酰胆碱受体对肌肉收缩至关重要。 | |
胆碱能受体 | Cholinergic receptors play a significant role in the autonomic nervous system. | 胆碱能受体在自主神经系统中发挥重要作用。 |
反义词
毒蕈碱型 | Muscarinic receptors are involved in parasympathetic responses. | 毒蕈碱型受体参与副交感神经反应。 | |
非尼古丁型 | Non-nicotinic pathways can affect different neurotransmitter systems. | 非尼古丁型通路可以影响不同的神经递质系统。 |
例句
1.Objective To observe the therapeutic effect of Nicotinic Acid Tablets in Acne vulgaris.
目的:观察烟酸对寻常型痤疮的治疗效果。
2.Addition of vitamin B6 is also involved in conversion of tryptophan to nicotinic acid and 5 - HT response.
此外维生素b6还参与色氨酸将烟酸转化为5—羟色胺的反应。
3.The terahertz (THz) spectra of nicotinic acid, nicotinamide and nicotine were studied at room temperature. The time-domain THz spectra were measured.
研究了室温条件下结构相似的烟酸和烟酰胺以及烟碱的太赫兹光谱。
4.A sensitive nicotinic sensor based on molecularly imprinted electropolymer of O-aminophenol was proposed, and its configuration and performance were studied.
研制了电化学聚合制备烟酸分子印迹聚邻氨基酚敏感膜传感器,并对分子印迹膜的结构和性能进行了探讨与研究。
5.Nicotinic acid sustained release tablet was prepared and its releasing features in vitro were evaluated.
制备烟酸缓释片剂,并评价其体外释放特性。
6.The manufacture process of nicotinic acid based on ammonia oxidation method, which is introduced in this article, reached 99% conversion of 3-methyl pyridine.
本文介绍的基于氨氧化法生产烟酸的工艺,选择了适当的复合催化剂,使原料3-甲基吡啶转化率可达99%,技术水平达到国外先进水平。
7.Using MRI scans, we have shown a reduction in the size of artery walls in patients after a year of treatment with nicotinic acid.
在经过烟碱酸类药物治疗1年后,通过MRI检查发现,患者的动脉壁的厚度下降。
8.The drug targets the nicotinic 尼古丁的 receptors in the brain to help reduce cravings.
该药物针对大脑中的nicotinic 尼古丁的受体,以帮助减少渴望。
9.Research shows that nicotinic 尼古丁的 acetylcholine receptors play a crucial role in cognitive function.
研究表明,nicotinic 尼古丁的乙酰胆碱受体在认知功能中起着至关重要的作用。
10.Smoking affects nicotinic 尼古丁的 pathways in the nervous system, leading to addiction.
吸烟影响神经系统中的nicotinic 尼古丁的通路,导致成瘾。
11.Some studies suggest that nicotinic 尼古丁的 stimulation can enhance memory and learning.
一些研究表明,nicotinic 尼古丁的刺激可以增强记忆和学习。
12.The new medication acts as a nicotinic 尼古丁的 agonist to help treat Alzheimer's disease.
这款新药作为一种nicotinic 尼古丁的激动剂,有助于治疗阿尔茨海默病。
作文
Nicotinic receptors play a crucial role in the functioning of the nervous system. These receptors, which are a type of acetylcholine receptor, are found in various locations throughout the body, including the brain, muscles, and autonomic ganglia. The term nicotinic refers to their sensitivity to nicotine, a substance commonly found in tobacco. When nicotine binds to these receptors, it triggers a series of responses that can affect mood, alertness, and even muscle contraction. This interaction highlights the importance of nicotinic receptors in both physiological and psychological processes. One of the most significant implications of nicotinic receptor activation is its impact on addiction. The pleasurable sensations that arise from nicotine consumption are largely due to its action on the brain's reward pathways. When nicotine stimulates nicotinic receptors in the brain, it leads to the release of dopamine, a neurotransmitter associated with pleasure and reinforcement. This mechanism explains why many individuals find it challenging to quit smoking or using tobacco products, as the brain becomes conditioned to seek out nicotine to experience those rewarding effects. Moreover, research has indicated that nicotinic receptors may also be involved in cognitive functions such as learning and memory. Studies have shown that stimulation of these receptors can enhance attention and improve memory performance. This is particularly interesting considering the potential therapeutic applications of nicotinic agonists in treating cognitive impairments associated with conditions like Alzheimer's disease. By targeting nicotinic receptors, researchers hope to develop treatments that can help improve cognitive function in affected individuals. In addition to their role in addiction and cognition, nicotinic receptors are also vital in muscle contraction. When acetylcholine is released at the neuromuscular junction, it binds to nicotinic receptors on muscle cells, leading to muscle contraction. This process is essential for voluntary movements and overall physical coordination. Disruption of this signaling pathway can lead to various neuromuscular disorders, highlighting the critical nature of nicotinic receptors in maintaining muscle health. Despite the negative connotations associated with nicotine and tobacco use, understanding nicotinic receptors provides valuable insights into both the challenges of addiction and the potential for therapeutic interventions. As scientists continue to explore the complexities of these receptors, new strategies may emerge to combat nicotine dependence and enhance cognitive function. Furthermore, the exploration of nicotinic receptor modulators could lead to innovative treatments for various neurological and psychiatric disorders. In conclusion, nicotinic receptors are integral components of the nervous system, influencing a wide range of functions from muscle contraction to cognitive processing. Their association with nicotine addiction underscores the need for continued research into their mechanisms and potential therapeutic applications. As we deepen our understanding of these receptors, we may uncover new ways to address the challenges posed by nicotine dependence and improve cognitive health in various populations.
烟碱受体在神经系统的功能中扮演着至关重要的角色。这些受体是一种乙酰胆碱受体,分布在身体的各个部位,包括大脑、肌肉和自主神经节。术语nicotinic指的是它们对尼古丁的敏感性,尼古丁是烟草中常见的物质。当尼古丁与这些受体结合时,会触发一系列反应,影响情绪、警觉性甚至肌肉收缩。这种相互作用突显了nicotinic受体在生理和心理过程中的重要性。 nicotinic受体激活的一个重要影响是其对成瘾的影响。尼古丁消费所带来的愉悦感主要归因于其对大脑奖励通路的作用。当尼古丁刺激大脑中的nicotinic受体时,会导致多巴胺的释放,这是一种与愉悦和强化相关的神经递质。这一机制解释了许多人为何发现戒烟或使用烟草产品如此困难,因为大脑逐渐习惯于寻求尼古丁以体验这些奖励效果。 此外,研究表明,nicotinic受体可能还与学习和记忆等认知功能有关。研究显示,刺激这些受体可以增强注意力并改善记忆表现。这一点尤其有趣,因为这为治疗阿尔茨海默病等疾病相关的认知障碍提供了潜在的治疗应用。通过靶向nicotinic受体,研究人员希望开发出能够帮助改善受影响个体认知功能的治疗方法。 除了在成瘾和认知中的作用外,nicotinic受体在肌肉收缩中也至关重要。当乙酰胆碱在神经肌肉接头释放时,它会与肌肉细胞上的nicotinic受体结合,从而导致肌肉收缩。这个过程对于自愿运动和整体身体协调至关重要。该信号通路的干扰可能导致各种神经肌肉疾病,突显了nicotinic受体在维持肌肉健康中的关键作用。 尽管尼古丁和烟草使用与负面含义相关,但理解nicotinic受体提供了对成瘾挑战和潜在治疗干预的宝贵见解。随着科学家们继续探索这些受体的复杂性,可能会出现新的策略来对抗尼古丁依赖并增强认知功能。此外,探索nicotinic受体调节剂可能会导致针对各种神经和精神疾病的创新治疗。 总之,nicotinic受体是神经系统的组成部分,影响从肌肉收缩到认知处理的广泛功能。它们与尼古丁成瘾的关联突显了对其机制和潜在治疗应用的持续研究的必要性。随着我们对这些受体理解的加深,我们可能会发现新的方法来应对尼古丁依赖所带来的挑战,并改善各类人群的认知健康。
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