nuclease

简明释义

英[ˈnjuːklɪˌeɪz]美[ˈnjʊklɪˌes]

n. [生化] 核酸酶

英英释义

单词用法

同义词

反义词

例句

1.In the past, researchers have looked for zinc-finger nuclease errors by assaying where in the genome the enzymes might bind, and checking to see whether those sequences were broken.

过去研究人员通过定位这种酶在基因组中的结合位点，之后检测这些序列是否受损的方法来寻找锌指核酸酶的错误。

2.The methods of nuclease extraction from malt root were studied in this paper.

主要研究了麦芽根中核酸酶的提取方法。

3.The unnatural backbone of PNAs also means that PNAs are particularly resistant to protease and nuclease degradation.

PNA的非天然骨架也使得PNA能有效对抗蛋白酶和核酸酶的降解。

4.In addition to introducing some new chemical nuclease systems, this paper stresses on the discussion of their action modes a...

本文除介绍了一些新的化学核酸酶体系外，着重对它们的作用方式及作用机理进行了讨论。

5.In addition to introducing some new chemical nuclease systems, this paper stresses on the discussion of their action modes and acting mechanisms.

本文除介绍了一些新的化学核酸酶体系外，着重对它们的作用方式及作用机理进行了讨论。

6.The team first identified a protein that had both a ubiquitin-binding domain and a known nuclease domain.

该研究小组首次证实存在有一种蛋白质，命名为KIAA1018，该蛋白质既有泛素结合区域，还有已知的核酸酶区域。

7.The zinc-finger design allows us to target a single gene, while the nuclease disrupts the gene.

我们可以通过对锌指的设计来靶向单个（特定的）基因，与此同时，核酸酶的存在将破坏该基因。

8.The enzyme nuclease is essential for DNA repair mechanisms.

酶核酸酶对DNA修复机制至关重要。

9.Researchers use nucleases to cut DNA at specific sites for genetic engineering.

研究人员使用核酸酶在特定位置切割DNA以进行基因工程。

10.The nuclease activity can be measured using gel electrophoresis.

可以通过凝胶电泳测量核酸酶的活性。

11.In molecular biology, nucleases play a crucial role in cloning processes.

在分子生物学中，核酸酶在克隆过程中发挥着至关重要的作用。

12.Some nucleases are used in the treatment of certain genetic disorders.

某些核酸酶用于治疗某些遗传疾病。

作文

Nucleases are enzymes that play a crucial role in the process of DNA and RNA metabolism. These enzymes are responsible for the cleavage of nucleic acids into smaller components, which is essential for various biological processes such as DNA replication, repair, and degradation. The importance of nuclease">核酸酶 cannot be overstated, as they are involved in maintaining the integrity of genetic material and regulating gene expression. There are two main types of nuclease">核酸酶: endonucleases and exonucleases. Endonucleases cut the phosphodiester bonds within a nucleic acid chain, resulting in the fragmentation of the molecule. This action is vital during DNA repair processes, where damaged sections of DNA need to be removed and replaced. On the other hand, exonucleases remove nucleotides one at a time from the ends of nucleic acid chains, which is important for processes such as the maturation of RNA molecules and the degradation of excess or damaged DNA. The discovery of nuclease">核酸酶 has significantly advanced our understanding of molecular biology. For instance, researchers have utilized these enzymes in recombinant DNA technology, allowing for the manipulation of genetic material in ways that were previously unimaginable. By using specific nuclease">核酸酶, scientists can cut DNA at precise locations, enabling them to insert, delete, or modify genes. This capability has paved the way for numerous applications, including gene therapy, agricultural biotechnology, and the production of genetically modified organisms (GMOs). Moreover, nuclease">核酸酶 are also essential tools in forensic science. They can be used to analyze DNA samples collected from crime scenes, helping to identify suspects or victims based on genetic evidence. The ability to amplify and analyze small amounts of DNA has revolutionized the field of forensics, making it possible to solve cases that would have otherwise remained unsolved. In addition to their applications in research and forensics, nuclease">核酸酶 also have therapeutic potential. Some diseases are caused by mutations in the genetic code, leading to the production of dysfunctional proteins. By using targeted nuclease">核酸酶 to edit the genome, researchers hope to correct these mutations and restore normal cellular function. This approach, known as gene editing, holds promise for treating genetic disorders, certain types of cancer, and viral infections. Despite the many benefits of nuclease">核酸酶, there are also ethical considerations that must be addressed. The power to alter an organism's genetic makeup raises questions about the potential consequences of such actions. It is crucial for scientists, ethicists, and policymakers to engage in discussions about the responsible use of these technologies to ensure that they are applied in ways that benefit society while minimizing risks. In conclusion, nuclease">核酸酶 are indispensable enzymes that facilitate the manipulation of nucleic acids, with far-reaching implications in biotechnology, forensics, and medicine. Their ability to cleave DNA and RNA allows researchers to explore the intricacies of genetic material, leading to advancements that could transform our understanding of biology and improve human health. As we continue to harness the power of nuclease">核酸酶, it is essential to remain mindful of the ethical implications and strive for responsible innovation in this rapidly evolving field.

核酸酶是参与DNA和RNA代谢过程的重要酶。这些酶负责将核酸切割成更小的组成部分，这对于DNA复制、修复和降解等各种生物过程至关重要。nuclease">核酸酶的重要性不容小觑，因为它们参与维持遗传物质的完整性和调节基因表达。 nuclease">核酸酶主要有两种类型：内切酶和外切酶。内切酶在核酸链内切断磷酸二酯键，从而导致分子碎片化。这一作用在DNA修复过程中至关重要，因为需要去除和替换受损的DNA部分。另一方面，外切酶从核酸链的末端逐个去除核苷酸，这对于RNA分子的成熟和多余或受损DNA的降解等过程非常重要。 nuclease">核酸酶的发现显著推动了我们对分子生物学的理解。例如，研究人员利用这些酶进行重组DNA技术，使得以往无法想象的方式操纵遗传物质成为可能。通过使用特定的nuclease">核酸酶，科学家可以在精确的位置切割DNA，从而实现基因的插入、删除或修改。这一能力为基因治疗、农业生物技术和转基因生物（GMO）的生产等众多应用铺平了道路。 此外，nuclease">核酸酶也是法医学中的重要工具。它们可以用于分析从犯罪现场收集的DNA样本，帮助根据遗传证据识别嫌疑人或受害者。放大和分析少量DNA的能力彻底改变了法医学领域，使得解决那些原本无法解决的案件成为可能。 除了在研究和法医学中的应用外，nuclease">核酸酶还具有治疗潜力。一些疾病是由基因组中的突变引起的，导致产生功能失常的蛋白质。通过使用靶向nuclease">核酸酶编辑基因组，研究人员希望纠正这些突变并恢复正常的细胞功能。这种被称为基因编辑的方法，对治疗遗传疾病、某些类型的癌症和病毒感染具有希望。 尽管nuclease">核酸酶有许多好处，但也存在需要解决的伦理问题。改变生物体遗传构成的能力引发了对这种行为潜在后果的质疑。科学家、伦理学家和政策制定者必须就这些技术的负责任使用进行讨论，以确保它们以造福社会的方式应用，同时将风险降至最低。 总之，nuclease">核酸酶是不可或缺的酶，促进了核酸的操控，在生物技术、法医学和医学中具有深远的意义。它们切割DNA和RNA的能力使研究人员能够探索遗传物质的复杂性，从而推动可能改变我们对生物学理解并改善人类健康的进步。随着我们继续利用nuclease">核酸酶的力量，保持对伦理影响的关注并在这一快速发展的领域中追求负责任的创新至关重要。