nucleocapsid

简明释义

英[ˌnjuːklɪə(ʊ)ˈkæpsɪd]美[ˌnʊklioˈkæpsɪd;ˌnjʊklioˈkæps

n. 核包核酸；[病毒] 病毒粒子；[病毒] 核蛋白壳；核壳体

英英释义

单词用法

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反义词

例句

1.Objective To study biochemical function and therapy of the NP (nucleocapsid protein) gene of NDV (new castle disease virus). Methods the purified genome RNA of NDV were used for template.

目的研究新城疫病毒(NDV)核衣壳蛋白(NP)基因的生物学作用及其抗人喉鳞癌的作用。

2.Antibody to nucleocapsid protein may be a potential target for early diagnosis.

核壳蛋白抗体可考虑用于早期诊断。

3.The method of indirect ELISA to detect CDV antibody in blood serum was established, using recombinant nucleocapsid protein as envelope antigen.

将表达的融合蛋白作为包被抗原，建立了间接酶联免疫吸附试验(间接elisa)的诊断方法以检测CDV血清抗体水平。

4.Nucleocapsid protein can bind genome RNA to shape neucleocapsid.

蛋白与基因组RNA结合形成核衣壳。

5.Two proteins of spike and one protein of nucleocapsid are identified.

得到两种纤突蛋白成分和一种核衣壳结构蛋白成分。

6.Conclusion Successful clone of an integrity SARS-CoV nucleocapsid gene and its effective expression in saccharomyces cerevisiae can be beneficial to the research on SARS vaccine.

结论：成功克隆SARS冠状病毒核衣壳蛋白基因全长，并在酿酒酵母中诱导表达成功，有助于抗sars分子疫苗的研究。

7.Numbers of nucleocapsids observed in an envelope in their cross sections ranged from 1 to 10, and the frequencies at 1 nucleocapsid was significantly higher than the others, almost 80.04% of the all.

通过多角体超薄切片的横切面观察，囊膜内包被的核衣壳数变动于1～10之间，只包被1个核衣壳的数目最多，约占总数的80.04％，病毒束在排列图式上存在差异。

8.Nucleocapsid (N) protein is highly conserved immunogenicity protein. In addition, N protein contains T cell epitope.

核衣壳（N）蛋白是保守性较强的免疫原性蛋白，此外N蛋白上含有T细胞表位。

9.The invention belongs to the technical field of bioseparation material, in particular to a magnetic composite microsphere with nucleocapsid structure and a preparation method thereof.

本发明属于生物分离材料技术领域，具体为一种具有核壳结构的磁性复合微球及其制备方法。

10.The structure of the virus is composed of a protein shell that encases the genetic material, known as the nucleocapsid.

病毒的结构由一个包裹遗传物质的蛋白质外壳组成，称为核衣壳。

11.Researchers are studying how the nucleocapsid interacts with host cell machinery during infection.

研究人员正在研究核衣壳在感染过程中如何与宿主细胞机制相互作用。

12.The stability of the nucleocapsid is crucial for the virus's ability to survive outside a host.

对于病毒在宿主外生存能力而言，核衣壳的稳定性至关重要。

13.Scientists have identified mutations in the nucleocapsid that may affect viral transmissibility.

科学家们已发现核衣壳中的突变，这可能会影响病毒的传播性。

14.The nucleocapsid plays a key role in the assembly of new viral particles.

核衣壳在新病毒颗粒的组装中起着关键作用。

作文

The structure and function of viruses have always fascinated scientists, particularly because of their unique way of hijacking host cells to reproduce. A crucial component of many viruses is the nucleocapsid, which serves as a protective shell for the viral genome. The nucleocapsid is composed of nucleic acids—either DNA or RNA—and proteins, forming a complex that is essential for the virus's life cycle. Understanding the nucleocapsid is vital for developing antiviral therapies and vaccines, as it plays a key role in the infection process. In simple terms, the nucleocapsid can be visualized as a suitcase containing the virus's genetic material. This 'suitcase' is not just a random assembly of parts; it is meticulously structured to ensure the stability and integrity of the viral genome. The proteins that make up the nucleocapsid are known as capsid proteins, which can vary significantly among different viruses. For instance, in some viruses, these proteins form intricate shapes that resemble geometric patterns, while in others, they create more amorphous structures. This diversity in structure allows viruses to adapt to various environments and hosts, showcasing the evolutionary prowess of these microscopic entities. Moreover, the nucleocapsid is involved in several critical functions beyond merely housing the viral genome. During the replication process, the nucleocapsid interacts with the host cell's machinery to facilitate the transcription and translation of viral proteins. This interaction is a prime target for antiviral drugs, as disrupting the formation or function of the nucleocapsid can prevent the virus from successfully replicating within the host. For example, some antiviral medications work by inhibiting the assembly of the nucleocapsid, thereby blocking the virus's ability to produce new viral particles. Furthermore, the nucleocapsid also plays a significant role in the immune response. When a virus infects a host, the immune system recognizes the foreign nucleocapsid proteins as potential threats, prompting an immune response. This recognition is crucial for vaccine development, as vaccines often aim to elicit an immune response against specific components of the nucleocapsid. By training the immune system to recognize and attack the viral nucleocapsid, vaccines can provide protection against future infections. In conclusion, the nucleocapsid is a fundamental aspect of viral biology that encompasses both structural and functional elements essential for viral replication and pathogenesis. Its role in protecting the viral genome, facilitating interactions with host cells, and eliciting immune responses underscores its importance in virology. As researchers continue to explore the intricacies of the nucleocapsid, we gain deeper insights into the mechanisms of viral infections and the development of effective therapeutic strategies. Understanding the nucleocapsid not only enhances our knowledge of virology but also paves the way for innovations in medical science, particularly in combating viral diseases that pose significant public health challenges worldwide.

病毒的结构和功能一直吸引着科学家的关注，特别是因为它们独特的劫持宿主细胞进行繁殖的方式。许多病毒的一个关键组成部分是核衣壳，它作为病毒基因组的保护壳。核衣壳由核酸——DNA或RNA——和蛋白质组成，形成一个对病毒生命周期至关重要的复合物。理解核衣壳对于开发抗病毒疗法和疫苗至关重要，因为它在感染过程中扮演着关键角色。 简单来说，核衣壳可以被视为一个装有病毒遗传物质的手提箱。这个“手提箱”并不是随意组合的零件；它经过精心构造，以确保病毒基因组的稳定性和完整性。构成核衣壳的蛋白质被称为衣壳蛋白，这些蛋白在不同病毒之间可能有显著差异。例如，在某些病毒中，这些蛋白形成复杂的形状，类似几何图案，而在其他病毒中，它们则形成更不规则的结构。这种结构上的多样性使病毒能够适应各种环境和宿主，展示了这些微观实体的进化能力。 此外，核衣壳在多个关键功能中也发挥着重要作用，超越了仅仅容纳病毒基因组的功能。在复制过程中，核衣壳与宿主细胞的机制相互作用，以促进病毒蛋白的转录和翻译。这种相互作用是抗病毒药物的主要目标，因为破坏核衣壳的形成或功能可以阻止病毒在宿主内成功复制。例如，一些抗病毒药物通过抑制核衣壳的组装来发挥作用，从而阻止病毒产生新的病毒颗粒。 此外，核衣壳在免疫反应中也发挥着重要作用。当病毒感染宿主时，免疫系统会将外来的核衣壳蛋白识别为潜在威胁，促使免疫反应的发生。这种识别对于疫苗开发至关重要，因为疫苗通常旨在引发针对核衣壳特定成分的免疫反应。通过训练免疫系统识别和攻击病毒的核衣壳，疫苗可以提供对未来感染的保护。 总之，核衣壳是病毒生物学的基本方面，涵盖了对病毒复制和致病性至关重要的结构和功能元素。它在保护病毒基因组、促进与宿主细胞的相互作用以及引发免疫反应中的作用突显了其在病毒学中的重要性。随着研究人员继续探索核衣壳的复杂性，我们对病毒感染机制和有效治疗策略的发展有了更深入的了解。理解核衣壳不仅增强了我们对病毒学的认识，而且为医学科学的创新铺平了道路，特别是在应对对全球公共卫生构成重大挑战的病毒疾病方面。