nucleotidase

简明释义

英[ˌnjuːklɪəˈtaɪdeɪs]美[ˌnʊkliəˈtaɪdes;ˌnʊkliəˈtaɪde

n. [生化] 核苷酸酶

英英释义

单词用法

同义词

反义词

例句

1.The kinetic properties of the 5-nucleotidase present in sytosol of 615 mice liver have been studied.

本文用生物化学的方法研究存在于615小鼠肝脏5’-核苷酶动力学性质。

2.The kinetic properties of the 5-nucleotidase present in sytosol of 615 mice liver have been studied.

本文用生物化学的方法研究存在于615小鼠肝脏5’-核苷酶动力学性质。

3.The enzyme nucleotidase plays a crucial role in nucleotide metabolism.

酶核苷酸酶在核苷酸代谢中起着至关重要的作用。

4.Research has shown that nucleotidase can affect the levels of ATP in cells.

研究表明，核苷酸酶可以影响细胞中ATP的水平。

5.Inhibitors of nucleotidase may have therapeutic potential for cancer treatment.

抑制核苷酸酶的药物可能在癌症治疗中具有治疗潜力。

6.The activity of nucleotidase is essential for DNA synthesis.

活性核苷酸酶对于DNA合成是必不可少的。

7.Scientists are studying the structure of nucleotidase to develop new drugs.

科学家们正在研究核苷酸酶的结构，以开发新药物。

作文

Nucleotidase is an important enzyme that plays a vital role in the metabolism of nucleotides, which are the building blocks of nucleic acids such as DNA and RNA. This enzyme catalyzes the hydrolysis of nucleotides into their constituent parts: a nitrogenous base, a sugar, and a phosphate group. Understanding the function of nucleotidase is crucial for various biological processes, including energy transfer and signal transduction within cells. In cellular metabolism, nucleotides serve not only as the structural units of genetic material but also as essential molecules involved in energy transfer. For instance, adenosine triphosphate (ATP), a nucleotide, is often referred to as the energy currency of the cell. The conversion of ATP to adenosine diphosphate (ADP) and inorganic phosphate is facilitated by the action of nucleotidase. This reaction releases energy that is harnessed for various cellular functions, such as muscle contraction, active transport, and biosynthesis. The activity of nucleotidase is not limited to ATP; it also acts on other nucleotides, including guanosine triphosphate (GTP) and cyclic adenosine monophosphate (cAMP). By breaking down these nucleotides, nucleotidase regulates their availability and thus modulates numerous signaling pathways. For example, cAMP is a crucial second messenger in many hormonal responses, and its levels are tightly controlled by the activity of nucleotidase and other enzymes. Moreover, the study of nucleotidase has significant implications in medicine and biotechnology. Abnormal levels or activity of this enzyme can be associated with various diseases, including cancer, where altered nucleotide metabolism is often observed. Researchers are investigating the potential of targeting nucleotidase as a therapeutic strategy to restore normal nucleotide balance in diseased cells. Additionally, the manipulation of nucleotidase activity can be utilized in biotechnological applications, such as the development of biosensors that monitor nucleotide levels in biological samples. In conclusion, nucleotidase is a key enzyme in the regulation of nucleotide metabolism, influencing both energy production and signaling pathways in cells. Its importance extends beyond basic biology, impacting fields such as medicine and biotechnology. A deeper understanding of nucleotidase will undoubtedly contribute to advancements in health and technology, highlighting the intricate connections between molecular biology and practical applications.

核苷酸酶是一种重要的酶，在核苷酸的代谢中扮演着至关重要的角色，核苷酸是DNA和RNA等核酸的基本组成部分。该酶催化核苷酸水解成其组成部分：一个氮碱、一个糖和一个磷酸基团。理解核苷酸酶的功能对各种生物过程至关重要，包括细胞内的能量转移和信号转导。 在细胞代谢中，核苷酸不仅作为遗传物质的结构单元，而且作为参与能量转移的基本分子。例如，三磷酸腺苷（ATP）是一种核苷酸，通常被称为细胞的能量货币。ATP转化为二磷酸腺苷（ADP）和无机磷酸的过程由核苷酸酶的作用促进。这个反应释放的能量被用于各种细胞功能，如肌肉收缩、主动转运和生物合成。 核苷酸酶的活性不仅限于ATP；它还作用于其他核苷酸，包括三磷酸鸟苷（GTP）和环腺苷单磷酸（cAMP）。通过分解这些核苷酸，核苷酸酶调节它们的可用性，从而调节众多信号通路。例如，cAMP是许多激素反应中的关键第二信使，其水平受到核苷酸酶和其他酶的严格控制。 此外，对核苷酸酶的研究在医学和生物技术中具有重要意义。该酶的异常水平或活性可能与各种疾病相关，包括癌症，其中常常观察到核苷酸代谢的改变。研究人员正在调查以核苷酸酶为靶点的潜在治疗策略，以恢复病变细胞中的正常核苷酸平衡。此外，操控核苷酸酶的活性可以用于生物技术应用，例如开发监测生物样本中核苷酸水平的生物传感器。 总之，核苷酸酶是调节核苷酸代谢的关键酶，影响细胞中的能量生产和信号通路。它的重要性超越了基础生物学，影响医学和生物技术等领域。对核苷酸酶的深入理解无疑将有助于健康和技术的进步，突显出分子生物学与实际应用之间的复杂联系。