oncogenesis

简明释义

英[ɒŋkəˈdʒenɪsɪs]美[ˌɒŋkoʊˈdʒenəsɪs]

n. 瘤形成

英英释义

单词用法

同义词

反义词

例句

1.This new paradigm of oncogenesis has been validated in a growing list of tumors.

这一新的癌变模式已在越来越多的肿瘤中得到证实。

2.Telomerase activation is essential for the stabilization of chromosomes in proliferation cells, leading to cellular immortality and oncogenesis.

端粒酶激活可以维持增殖细胞染色体的稳定性，导致细胞永生化和肿瘤发生。

3.Its scope of the science spans such diverse areas as cell cycle progression, cell differentiation, oncogenesis, chromosome biology, neuronal guidance and stem cell biology.

该所的科学范围涉及细胞周期，细胞分化，肿瘤形成，染色体生物学，神经元引导，和干细胞生物学等多个领域。

4.With all the important advances in genomic sequencing, one can sometimes forget that molecular oncologists have been busy for decades to uncover what happens at the molecular level in oncogenesis.

随着所有基因组测序的重要进展，我们有时可能忘记，分子肿瘤学家数十年来一直忙于揭示肿瘤在分子水平是如何发生的。

5.PML is a growth and transformation suppressor, and it may play a role in the oncogenesis of solid tumors.

PML是一个生长和转录抑制因子，研究表明PML表达变化可能和一些实体癌的发生有关。

6.Conclusion Telomere reduction and telomerase activation are critical factor during oncogenesis.

结论端粒缩短并激活端粒酶是涎腺肿瘤形成的重要因素。

7.Like all the other cancers, the oncogenesis of pancreatic cancer is also a complicated pathological process involves many factors, many genes and many stages.

与所有肿瘤一样，胰腺癌的发生也是一种多因素作用，多基因参与，多阶段形成的复杂病理过程。

8.Activation of telomerase is the critical step in cellular immortality and oncogenesis. Its activity is controled by many factors.

端粒酶激活是细胞永生化和肿瘤形成的关键步骤，其活性受到多种因素的调控。

9.Research into the mechanisms of oncogenesis 肿瘤发生 has revealed several key genetic mutations.

对肿瘤发生机制的研究揭示了几个关键的基因突变。

10.Understanding oncogenesis 肿瘤发生 can help in developing targeted cancer therapies.

理解肿瘤发生有助于开发靶向癌症治疗方法。

11.The study focused on the role of inflammation in oncogenesis 肿瘤发生 and its implications for treatment.

该研究集中在炎症在肿瘤发生中的作用及其对治疗的影响。

12.Researchers are investigating how environmental factors contribute to oncogenesis 肿瘤发生 in different populations.

研究人员正在调查环境因素如何影响不同人群的肿瘤发生。

13.The link between viral infections and oncogenesis 肿瘤发生 is an important area of cancer research.

病毒感染与肿瘤发生之间的联系是癌症研究的重要领域。

作文

Oncogenesis is a complex process that leads to the formation of cancer. Understanding this intricate phenomenon is crucial for both medical professionals and the general public. The term itself derives from the Greek words 'onkos,' meaning mass or tumor, and 'genesis,' meaning origin or creation. Thus, oncogenesis (肿瘤发生) refers to the genesis or development of tumors in the body. The journey of oncogenesis begins at the cellular level. Normally, cells grow, divide, and die in a regulated manner. However, when this regulation is disrupted, cells may begin to proliferate uncontrollably. This uncontrolled growth is often triggered by mutations in the DNA of the cells. These mutations can be caused by various factors, including environmental influences such as radiation, chemicals, and viruses, as well as inherited genetic predispositions. One of the key players in oncogenesis is the concept of oncogenes and tumor suppressor genes. Oncogenes are mutated forms of normal genes that, when activated, promote cell division and survival. In contrast, tumor suppressor genes normally act to inhibit cell division and promote apoptosis, or programmed cell death. When these tumor suppressor genes are inactivated due to mutations, the balance is tipped in favor of cell proliferation, leading to the development of tumors. The progression of oncogenesis typically occurs in several stages, starting with the initiation phase, where the first mutations occur. This is followed by promotion, where the mutated cells begin to proliferate. Finally, in the progression phase, further mutations accumulate, leading to more aggressive and invasive cancer characteristics. Research into oncogenesis has significant implications for cancer treatment and prevention. By understanding the mechanisms behind tumor formation, scientists can develop targeted therapies that specifically attack cancer cells while sparing normal cells. For example, drugs that inhibit specific oncogenes or restore the function of tumor suppressor genes are currently being explored in clinical trials. Moreover, knowledge of oncogenesis can aid in cancer prevention strategies. Lifestyle choices, such as avoiding tobacco, maintaining a healthy diet, and protecting oneself from excessive sun exposure, can reduce the risk of mutations that lead to cancer. Additionally, early detection through regular screenings can catch cancers at an earlier, more treatable stage. In conclusion, oncogenesis (肿瘤发生) is a critical area of study that encompasses the biological, environmental, and genetic factors contributing to cancer development. By continuing to explore the intricacies of this process, we can enhance our understanding of cancer and improve outcomes for those affected by this devastating disease. As research progresses, we remain hopeful that advancements in our comprehension of oncogenesis will lead to more effective treatments and preventive measures, ultimately reducing the burden of cancer on society.