osteopetrosis

简明释义

英[ˌɒstɪəʊpeˈtrəʊsɪs]美[ɑːstɪoʊpɪˈtroʊsɪs]

n. [外科] 骨硬化病

英英释义

单词用法

同义词

反义词

例句

1.Conclusion. This case report discusses the rare occurrence of multiple lumbar pedicle fractures and pars interarticularis (spondylolysis) fractures in a patient with osteopetrosis.

结论：本文就一例少见的复发性多处腰椎椎弓根骨折伴椎弓峡部骨折的石骨症病例的相关问题进行了讨论。

2.Conclusion. This case report discusses the rare occurrence of multiple lumbar pedicle fractures and pars interarticularis (spondylolysis) fractures in a patient with osteopetrosis.

结论：本文就一例少见的复发性多处腰椎椎弓根骨折伴椎弓峡部骨折的石骨症病例的相关问题进行了讨论。

3.Summary of Background Data. Osteopetrosis is characterized by osteoclast dysfunction, impaired bone resorption, and poor bone remodeling.

石骨症的特征是破骨细胞功能出现障碍，使骨吸收减慢，导致骨再建缺陷。

4.The authors treated a 6-month-old boy with malignant infantile osteopetrosis using bone marrow transplantation.

作者使用骨髓移植治疗一个6个月大的有恶性的婴儿骨硬化病的男孩。

5.Objective To discuss the clinical and pathological features of bone marrow biopsy of osteopetrosis.

目的探讨石骨症的骨髓活检的临床病理特点。

6.Objective To investigate the features of genetic and clinical manifestation of osteopetrosis.

目的探讨家族性石骨症的遗传、临床及X线表现特点。

7.So it can be used in the treatment of osteopetrosis.

而且可以抑制破骨细胞凋亡，因而可用于治疗骨骼石化症。

8.The patient was diagnosed with osteopetrosis, a condition characterized by abnormally dense bones.

患者被诊断为骨质硬化症，这种疾病的特征是骨骼异常密集。

9.Children with osteopetrosis often experience frequent fractures due to brittle bones despite their density.

患有骨质硬化症的儿童由于骨骼脆弱，尽管骨骼密度高，仍然经常骨折。

10.Research is ongoing to find effective treatments for osteopetrosis that can improve the quality of life for patients.

研究正在进行，以寻找有效的治疗骨质硬化症的方法，以改善患者的生活质量。

11.Symptoms of osteopetrosis may include bone pain, fractures, and dental problems.

症状可能包括骨痛、骨折和牙齿问题的骨质硬化症。

12.The genetic basis of osteopetrosis has been identified, leading to better diagnostic tools.

已确定骨质硬化症的遗传基础，这为更好的诊断工具铺平了道路。

作文

Osteopetrosis is a rare bone disease that affects the density and strength of bones. The term 'osteopetrosis' comes from the Greek words 'osteo,' meaning bone, and 'petrosus,' meaning rock-like. This condition causes bones to become overly dense and hard, resembling stone. While this might sound beneficial at first glance, the reality is quite different. Individuals with osteopetrosis (骨质硬化症) often experience a range of complications due to the abnormal bone structure. One of the main issues with osteopetrosis (骨质硬化症) is that it can lead to decreased bone strength despite increased density. The bones may become brittle and more prone to fractures. Additionally, the excessive density can lead to problems with bone marrow, where blood cells are produced. As a result, patients may suffer from anemia, frequent infections, and bleeding disorders. The bone marrow becomes compressed due to the thickened bones, which hampers its ability to function properly. There are two major types of osteopetrosis (骨质硬化症): autosomal dominant and autosomal recessive. The dominant form is typically milder and may not be diagnosed until adulthood, whereas the recessive form is more severe and usually presents in infancy. Children with the recessive form often face significant health challenges early in life, including growth delays and skeletal deformities. Diagnosis of osteopetrosis (骨质硬化症) usually involves imaging studies such as X-rays or CT scans, which reveal the characteristic dense bones. Blood tests may also be conducted to check for anemia or other related conditions. Early diagnosis is crucial, as it allows for timely intervention and management of symptoms. Treatment options for osteopetrosis (骨质硬化症) vary depending on the severity of the condition. In some cases, supportive care may be sufficient to manage symptoms. This can include pain management, physical therapy, and regular monitoring of blood counts. For more severe cases, treatments like bone marrow transplantation have shown promise, particularly in young children. This procedure aims to restore normal bone marrow function, potentially reversing some of the complications associated with osteopetrosis (骨质硬化症). Research continues to explore new therapies for osteopetrosis (骨质硬化症), including gene therapy and medications that may help regulate bone density. Education and awareness about this condition are essential for both patients and healthcare providers, as recognizing the symptoms early can significantly improve outcomes. In conclusion, osteopetrosis (骨质硬化症) is a complex and challenging condition that requires a multidisciplinary approach for effective management. Understanding the implications of this disease on an individual's overall health is vital for providing appropriate care and support. With ongoing research and advancements in treatment, there is hope for better management strategies for those affected by osteopetrosis (骨质硬化症).

骨质硬化症是一种罕见的骨病，影响骨骼的密度和强度。术语“骨质硬化症”源自希腊词“osteo”，意为骨头，以及“petrosus”，意为岩石状。这种病症导致骨骼过于密集和坚硬，类似于石头。虽然乍一看这似乎是有益的，但现实却截然不同。患有骨质硬化症的人（osteopetrosis）通常由于异常的骨结构而经历一系列并发症。 骨质硬化症的主要问题之一（osteopetrosis）是尽管密度增加，但可能导致骨强度下降。骨骼可能变得脆弱，更容易骨折。此外，过度的密度可能导致骨髓问题，血细胞在这里生成。因此，患者可能会遭受贫血、频繁感染和出血障碍。由于增厚的骨骼，骨髓受到压迫，妨碍其正常功能。 骨质硬化症有两种主要类型（osteopetrosis）：常染色体显性和常染色体隐性。显性形式通常较温和，可能直到成年才被诊断，而隐性形式则更为严重，通常在婴儿期就会出现。患有隐性形式的儿童往往在生命早期面临重大健康挑战，包括生长延迟和骨骼畸形。 骨质硬化症的诊断通常涉及成像研究，如X光或CT扫描，这些检查显示出特征性的密骨。还可能进行血液测试，以检查贫血或其他相关疾病。早期诊断至关重要，因为它允许及时干预和症状管理。 对于骨质硬化症的治疗（osteopetrosis），取决于病情的严重程度，治疗选项各不相同。在某些情况下，支持性护理可能足以管理症状。这可以包括疼痛管理、物理治疗和定期监测血液计数。对于更严重的病例，骨髓移植等治疗显示出希望，特别是在幼儿中。这一程序旨在恢复正常的骨髓功能，潜在地逆转与骨质硬化症相关的一些并发症。 研究继续探索骨质硬化症的新疗法（osteopetrosis），包括基因治疗和可能帮助调节骨密度的药物。提高对这种病症的教育和意识对患者和医疗提供者都是至关重要的，因为及早识别症状可以显著改善结果。 总之，骨质硬化症是一种复杂且具有挑战性的疾病，需要多学科的方法进行有效管理（osteopetrosis）。理解这种疾病对个体整体健康的影响对于提供适当的护理和支持至关重要。随着研究的不断推进和治疗的进步，患有骨质硬化症的人（osteopetrosis）有望获得更好的管理策略。