ototoxicity

简明释义

英[/ˌoʊtəʊtɒkˈsɪtɪ/]美[/ˌoʊtəʊtɒkˈsɪtɪ/]

n. 耳毒性

英英释义

单词用法

同义词

反义词

例句

1.The problem with these antibiotics is that they have serious adverse effects such as nephrotoxicity, ototoxicity and peripheral neuropathy that limit the length of time that they can be used.

但这些抗生素副作用较大，如肾脏毒性、耳毒性和外周神经毒性等，限制了用药疗程。

2.Objective To observe protection effects of glutathione against gentamicin ototoxicity and to compare the effects between two different administration methods of glutathione.

目的观察还原型谷胱甘肽对庆大霉素耳蜗毒性的拮抗效果，并且比较了两种给药方法对其效果的影响。

3.Objective to investigate the ototoxicity of a new chemical preparation salicylate gentamicin.

目的探讨庆大霉素新剂型-水杨酸庆大霉素的耳毒性。

4.Objective: to further understand the mechanism of salicylate ototoxicity.

目的：探讨水杨酸钠耳毒性的发生机制。

5.Objective to study the protective effect of dexamethasone and flunarizine on gentamicin ototoxicity.

目的探讨地塞米松和西比灵对庆大霉素耳毒性的保护作用。

6.The problem with these antibiotics is that they have serious adverse effects such as nephrotoxicity, ototoxicity and peripheral neuropathy that limit the length of time that they can be used.

但这些抗生素副作用较大，如肾脏毒性、耳毒性和外周神经毒性等，限制了用药疗程。

7.Conclusion: Angelica injection can reduce ge ototoxicity.

结论当归注射液能降低GE的耳毒性。

8.Objective to explore the effect of hyperbaric oxygen on gentamicin-induced ototoxicity in guinea pigs.

目的探讨高压氧对庆大霉素耳毒性的影响。

9.Some antibiotics have been linked to ototoxicity, which can cause hearing loss.

一些抗生素与耳毒性有关，可能导致听力损失。

10.Patients receiving chemotherapy should be monitored for signs of ototoxicity.

接受化疗的患者应该监测耳毒性的迹象。

11.The doctor explained that ototoxicity could result from long-term use of certain medications.

医生解释说，长期使用某些药物可能会导致耳毒性。

12.Hearing specialists often test for ototoxicity in patients who have taken high doses of aspirin.

听力专家通常会对服用高剂量阿司匹林的患者进行耳毒性测试。

13.Certain environmental factors can also contribute to ototoxicity.

某些环境因素也可能导致耳毒性。

作文

Ototoxicity is a term that refers to the property of being toxic to the ear, specifically the inner ear structures which are responsible for hearing and balance. This condition can arise from various sources, including certain medications, environmental toxins, and even some infections. Understanding ototoxicity is crucial, especially for individuals who may be at risk due to their medical treatments or exposure to harmful substances. In the medical field, many healthcare professionals are aware of the potential risks associated with ototoxicity. Some common medications known to cause this condition include aminoglycoside antibiotics, loop diuretics, and platinum-based chemotherapy agents. These drugs can damage the hair cells in the cochlea, leading to hearing loss or balance issues. For instance, a patient undergoing treatment for cancer may be prescribed cisplatin, which has been linked to ototoxicity. As such, it is vital for doctors to monitor patients closely and consider alternative treatments when possible. The impact of ototoxicity extends beyond just the medical implications; it can significantly affect an individual's quality of life. Hearing loss can lead to difficulties in communication, social isolation, and even depression. Furthermore, balance issues caused by ototoxicity can increase the risk of falls, particularly in older adults. Therefore, early detection and intervention are essential to mitigate these adverse effects. Audiologists and other specialists often recommend regular hearing assessments for patients at risk of ototoxicity to catch any changes in hearing ability as soon as they occur. In addition to medication-related causes, environmental factors can also contribute to ototoxicity. Prolonged exposure to loud noises, for instance, can lead to irreversible damage to the auditory system. Occupational settings, such as construction sites or factories, often expose workers to high levels of noise, increasing their risk of developing hearing problems. It is imperative for employers to implement safety measures, such as providing hearing protection and conducting regular hearing tests, to protect their employees from the harmful effects of ototoxicity. Moreover, research is ongoing to better understand the mechanisms behind ototoxicity and how to prevent it. Scientists are investigating potential protective agents that could be administered alongside ototoxic drugs to shield the inner ear from damage. Additionally, studies are exploring genetic factors that may predispose certain individuals to ototoxicity, allowing for more personalized approaches to treatment. In conclusion, ototoxicity is a significant concern in both medical and environmental contexts. Awareness and understanding of this condition are critical for healthcare providers, patients, and the general public. By recognizing the risks associated with certain medications and environmental exposures, we can take proactive steps to minimize the impact of ototoxicity on our lives. Whether through regular hearing evaluations, the use of protective equipment in noisy environments, or ongoing research into preventive measures, addressing ototoxicity is essential for preserving our auditory health and overall well-being.

耳毒性是指对耳朵，特别是负责听觉和平衡的内耳结构具有毒性的性质。这种情况可能由多种来源引起，包括某些药物、环境毒素甚至一些感染。理解耳毒性至关重要，尤其是对于那些由于医疗治疗或接触有害物质而可能面临风险的个人。 在医学领域，许多医疗专业人员都意识到与耳毒性相关的潜在风险。一些已知会导致这种情况的常见药物包括氨基糖苷类抗生素、袢利尿剂和铂类化疗药物。这些药物可能损害耳蜗中的毛细胞，从而导致听力损失或平衡问题。例如，接受癌症治疗的患者可能会被开处方顺铂，而这种药物与耳毒性有关。因此，医生密切监测患者并在可能的情况下考虑替代治疗至关重要。 耳毒性的影响不仅限于医学层面；它还可能显著影响个人的生活质量。听力损失可能导致沟通困难、社交孤立甚至抑郁。此外，由于耳毒性引起的平衡问题可能增加跌倒的风险，尤其是在老年人中。因此，早期检测和干预对于减轻这些不良影响至关重要。听力学家和其他专家通常建议对有耳毒性风险的患者进行定期听力评估，以便尽早发现听力能力的变化。 除了药物相关的原因，环境因素也可能导致耳毒性。例如，长期暴露于噪音中可能导致听觉系统的不可逆损伤。职业环境，如建筑工地或工厂，通常使工人暴露于高噪音水平，从而增加他们发展听力问题的风险。雇主必须采取安全措施，例如提供听力保护和定期进行听力测试，以保护员工免受耳毒性的有害影响。 此外，研究仍在持续进行，以更好地理解耳毒性背后的机制以及如何预防它。科学家们正在研究潜在的保护剂，可以与耳毒性药物一起使用，以保护内耳免受损害。此外，研究还在探索可能使某些个体易感于耳毒性的遗传因素，从而允许更个性化的治疗方法。 总之，耳毒性在医学和环境背景中都是一个重要问题。对这种情况的认识和理解对医疗提供者、患者和公众至关重要。通过识别与某些药物和环境暴露相关的风险，我们可以采取积极措施来最小化耳毒性对我们生活的影响。无论是通过定期听力评估、在嘈杂环境中使用保护设备，还是对预防措施的持续研究，解决耳毒性问题对于保护我们的听力健康和整体福祉至关重要。