paclitaxel

简明释义

英[ˌpæklɪˈtæksəl]美[ˌpæklɪˈtæksəl]

n. 紫杉醇

英英释义

单词用法

同义词

反义词

例句

1.OBJECTIVE To study the influence of interior gelatinization on the stability of freeze dried liposomes with paclitaxel loaded.

目的制备载紫杉醇内部胶凝化脂质体，考察内部胶凝在冷冻干燥中对脂质体的稳定作用。

2.To investigate the proliferative effect of paclitaxel against humananaplastic thyroid carcinoma cells (DRO).

观察不同浓度的紫杉醇对人甲状腺未分化癌细胞DRO生长的影响。

3.Paclitaxel adheres to the balloon until it is expanded.

直到球囊展开，紫杉醇一直粘附在其上面。

4.OBJECTIVE To study the preparation of paclitaxel entrapped magnetic non ionic surfactant vesicles (tax MNS) and evaluate its quality.

目的：对紫杉醇磁性非离子表面活性剂泡囊的处方和制备工艺进行研究，并评价其质量。

5.Results: Paclitaxel inhibited the growth of A375 cells by inducing apoptosis in a both time-dependent and dose-dependent manner(P<0.01).

结果：紫杉醇通过诱导细胞凋亡抑制A375细胞生长，并呈时间和剂量依赖性（P<0.01）；

6.Objective to evaluate the relation of dose intensity and efficacy, toxicity in advanced breast cancer treated with paclitaxel as a single agent.

目的分析单药紫杉醇治疗晚期乳腺癌剂量强度与疗效和毒性的关系。

7.Paclitaxel is a chemotherapy drug commonly used to treat breast and ovarian cancer, but some tumours can become resistant over time and start growing again.

紫杉醇是一种常用于治疗乳腺癌和卵巢癌的化疗药物，但是，随着用药时间的延长，一些肿瘤可以对其产生抗药性，而又开始生长了。

8.The oncologist prescribed paclitaxel for the patient's breast cancer treatment.

肿瘤科医生为患者的乳腺癌治疗开了紫杉醇。

9.Many patients experience side effects from paclitaxel, such as hair loss and nausea.

许多患者在使用紫杉醇时会出现副作用，如脱发和恶心。

10.Clinical trials are ongoing to evaluate the effectiveness of paclitaxel in combination with other drugs.

临床试验正在进行中，以评估紫杉醇与其他药物联合使用的有效性。

11.The administration of paclitaxel is often done through an intravenous infusion.

通常通过静脉输注来给药紫杉醇。

12.Patients should be monitored closely for allergic reactions after receiving paclitaxel.

接受紫杉醇后，患者应密切监测过敏反应。

作文

Paclitaxel is a chemotherapeutic agent that has gained significant attention in the field of oncology. Originally derived from the bark of the Pacific yew tree, its discovery marked a turning point in cancer treatment. The drug works by interfering with the normal function of microtubules during cell division, effectively preventing cancer cells from dividing and growing. This mechanism of action makes paclitaxel particularly effective against various types of cancer, including breast, ovarian, and lung cancers. The journey of paclitaxel from a natural product to a widely used chemotherapy drug is fascinating. Researchers initially isolated the compound in the 1960s, but it wasn't until the 1990s that it was approved for clinical use. Its effectiveness in treating advanced-stage cancers has made it a cornerstone of many chemotherapy regimens. However, like all medications, paclitaxel comes with its own set of side effects, which can range from hair loss and nausea to more severe complications such as neuropathy and allergic reactions. One of the significant challenges in using paclitaxel is the development of resistance by cancer cells. Over time, some tumors may become less responsive to the drug, prompting researchers to explore combination therapies that can enhance its efficacy. For instance, combining paclitaxel with other agents can sometimes overcome resistance and improve patient outcomes. This approach is crucial as it not only maximizes the potential of paclitaxel but also provides patients with a more comprehensive treatment plan. In addition to its use in traditional chemotherapy, paclitaxel has also been investigated for its role in targeted therapy. Researchers are exploring ways to deliver paclitaxel directly to cancer cells while minimizing exposure to healthy tissues. This targeted delivery system aims to reduce side effects and enhance the overall effectiveness of the treatment. Furthermore, ongoing studies are examining the potential of paclitaxel in treating other diseases beyond cancer. Its properties may offer therapeutic benefits in conditions such as cardiovascular diseases and certain inflammatory disorders. This broadens the scope of paclitaxel and highlights the importance of continued research in understanding the full potential of this compound. In conclusion, paclitaxel represents a significant advancement in cancer treatment, providing hope to many patients facing challenging diagnoses. While its journey has not been without obstacles, the ongoing research and development surrounding paclitaxel continue to pave the way for innovative therapies. As we learn more about its mechanisms and applications, paclitaxel may not only remain a vital tool in oncology but could also expand into new therapeutic areas, ultimately improving patient care and outcomes.

紫杉醇是一种化疗药物，在肿瘤学领域引起了广泛关注。它最初是从太平洋紫杉树的树皮中提取的，其发现标志着癌症治疗的一个重要转折点。这种药物通过干扰细胞分裂过程中微管的正常功能，有效地阻止癌细胞的分裂和生长。这一作用机制使得紫杉醇对多种类型的癌症特别有效，包括乳腺癌、卵巢癌和肺癌。 紫杉醇从天然产品到广泛使用的化疗药物的旅程令人着迷。研究人员在20世纪60年代首次分离出这种化合物，但直到90年代才获得临床使用的批准。它在治疗晚期癌症方面的有效性使其成为许多化疗方案的基石。然而，像所有药物一样，紫杉醇也有自己的副作用，可能包括脱发、恶心以及更严重的并发症，如神经病和过敏反应。 使用紫杉醇的一大挑战是癌细胞的耐药性发展。随着时间的推移，一些肿瘤可能对该药物的反应降低，这促使研究人员探索可以增强其疗效的联合疗法。例如，将紫杉醇与其他药物结合，有时可以克服耐药性，提高患者的预后。这种方法至关重要，因为它不仅最大化了紫杉醇的潜力，还为患者提供了更全面的治疗方案。 除了在传统化疗中的应用外，研究人员还在调查紫杉醇在靶向治疗中的作用。研究人员正在探索将紫杉醇直接输送到癌细胞的方法，同时尽量减少对健康组织的暴露。这种靶向递送系统旨在减少副作用，提高治疗的整体有效性。 此外，正在进行的研究还在考察紫杉醇在治疗癌症以外的其他疾病中的潜力。它的特性可能在心血管疾病和某些炎症性疾病中提供治疗益处。这扩大了紫杉醇的范围，并突显了持续研究的重要性，以理解这种化合物的全部潜力。 总之，紫杉醇代表了癌症治疗的重要进展，为许多面临挑战性诊断的患者提供了希望。尽管它的旅程并非没有障碍，但围绕紫杉醇的持续研究和开发继续为创新疗法铺平道路。随着我们对其机制和应用的了解加深，紫杉醇不仅可能在肿瘤学中保持作为一种重要工具的地位，还可能扩展到新的治疗领域，最终改善患者护理和结果。