penicillamine

简明释义

英[ˌpenɪsɪˈlæmɪn]美[ˌpenɪˈsɪləˌmin]

n. [药] 青霉胺

英英释义

单词用法

同义词

反义词

例句

1.In recent years clinical common penicillamine, glucocorticoid and other drugs to treat the disease, not only long course of treatment, the treatment ineffective, and have more adverse reactions.

近年来临床上常用青霉胺、糖皮质激素等药物治疗此病，不但疗程长，治疗效果不明显，且不良反应也较多。

2.In recent years clinical common penicillamine, glucocorticoid and other drugs to treat the disease, not only long course of treatment, the treatment ineffective, and have more adverse reactions.

近年来临床上常用青霉胺、糖皮质激素等药物治疗此病，不但疗程长，治疗效果不明显，且不良反应也较多。

3.Conclusions: Penicillamine has great effect to inhibit intra-abdominal adhesion formation and reduce the wound breaking strength, but it has no influence on wound healing.

结论：青霉胺具有明显预防腹腔粘连的作用，降低刀口抗张力而不影响刀口愈合。

4.After discharge, the maintaining therapy given to them was dimercaptosuccinic acid and penicillamine alternatively combined with Gandou tablet and zinc gluconate orally.

出院后予二巯基丁二酸和青霉胺交替服用，并同时服肝豆片和葡萄糖酸锌以维持治疗。

5.Conclusion Indirect moxibustion and penicillamine are similar in curative effect. Indirect moxibustion can be regarded as an effective therapy for rheumatoid arthritis.

结论间接灸与青霉胺疗效相仿，间接灸治疗类风湿性关节炎可视作一种有效的方法。

6.PURPOSE To compare the efficacy and urinary copper excretion in the treatment of hepatolenticular degeneration (HLD) with penicillamine and zinc.

比较青霉胺及锌剂治疗肝豆状核变性（HLD）的疗效及对尿铜排泄的作用。

7.Objective To improve clinicians 'understanding of nephrotic syndrome and myasthenia gravis as adverse events of penicillamine (D-PA).

目的提高临床医生对青霉胺(D - PA)致肾病综合征和重症肌无力的认识。

8.Objective To determine the best plan with penicillamine in treating the patients with hepatolenticular degeneration.

目的探讨青霉胺治疗肝豆状核变性的最佳方案。

9.The doctor prescribed penicillamine to help treat the patient's rheumatoid arthritis.

医生开了青霉胺来帮助治疗患者的类风湿性关节炎。

10.Due to its effectiveness, penicillamine is often used in cases of heavy metal poisoning.

由于其有效性，青霉胺常用于重金属中毒的情况。

11.Patients taking penicillamine should be monitored for potential side effects.

服用青霉胺的患者应监测潜在的副作用。

12.Before starting penicillamine, the patient underwent a series of blood tests.

在开始服用青霉胺之前，患者进行了系列血液检测。

13.The effectiveness of penicillamine can vary from person to person.

每个人对青霉胺的有效性可能有所不同。

作文

Penicillamine is a medication that has been used for various medical conditions, particularly in the treatment of rheumatoid arthritis and Wilson's disease. This compound, derived from penicillin, plays a significant role in chelating heavy metals in the body, making it an essential drug for those suffering from metal toxicity. Understanding the function and implications of penicillamine is crucial for both patients and healthcare providers alike. Rheumatoid arthritis is an autoimmune disorder characterized by chronic inflammation of the joints. Patients often experience pain, swelling, and stiffness, which can severely impact their quality of life. Traditional treatments include non-steroidal anti-inflammatory drugs (NSAIDs) and corticosteroids; however, these may not be effective for everyone. Here, penicillamine comes into play as a disease-modifying antirheumatic drug (DMARD). It helps to reduce inflammation and slow down the progression of the disease by altering the immune response. On the other hand, Wilson's disease is a genetic disorder that leads to excessive accumulation of copper in the body, resulting in liver and neurological damage. The use of penicillamine in this context is vital as it binds to copper, allowing for its excretion through the kidneys. This chelation process helps prevent the toxic buildup of copper, thereby protecting the organs from irreversible damage. While penicillamine has proven to be effective, it is not without side effects. Patients may experience allergic reactions, skin rashes, or gastrointestinal issues. Additionally, because it alters the immune system, there is a risk of developing infections. Therefore, monitoring by healthcare professionals is essential during treatment. Regular blood tests are often required to check for any adverse effects, especially concerning kidney function and blood cell counts. It is also important to note that penicillamine should be taken with caution in combination with other medications. Certain drugs can interact negatively with penicillamine, leading to reduced effectiveness or increased toxicity. Patients must inform their doctors about all medications they are taking to avoid potential complications. In conclusion, penicillamine serves as a valuable tool in the management of specific medical conditions. Its ability to modify disease activity in rheumatoid arthritis and to chelate excess copper in Wilson's disease highlights its importance in clinical practice. However, like any medication, it requires careful consideration and monitoring. By understanding the benefits and risks associated with penicillamine, patients and healthcare providers can work together to ensure optimal treatment outcomes. As research continues, we may uncover more uses for this versatile drug, potentially improving the lives of many patients worldwide.

青霉胺是一种药物，已被用于多种医疗条件，特别是在治疗类风湿关节炎和威尔逊病方面。这种源自青霉素的化合物在体内螯合重金属方面发挥着重要作用，使其成为那些遭受金属毒性患者的重要药物。理解青霉胺的功能和含义对于患者和医疗保健提供者都至关重要。 类风湿关节炎是一种自身免疫性疾病，其特征是关节的慢性炎症。患者常常感到疼痛、肿胀和僵硬，这可能严重影响他们的生活质量。传统治疗包括非甾体抗炎药（NSAIDs）和皮质类固醇；然而，并非所有患者都能有效控制症状。在这种情况下，青霉胺作为一种改变疾病进程的抗风湿药物（DMARD）出现。它通过改变免疫反应来帮助减少炎症并减缓疾病的进展。 另一方面，威尔逊病是一种遗传性疾病，导致体内铜的过量积累，进而造成肝脏和神经系统的损害。在这种情况下使用青霉胺至关重要，因为它能与铜结合，使其通过肾脏排泄。这个螯合过程有助于防止铜的毒性积聚，从而保护器官免受不可逆转的损害。 虽然青霉胺已被证明是有效的，但并非没有副作用。患者可能会经历过敏反应、皮疹或胃肠道问题。此外，由于它会改变免疫系统，因此存在发展感染的风险。因此，在治疗期间，医疗专业人员的监测至关重要。通常需要定期进行血液检查，以检查任何不良反应，尤其是关于肾功能和血细胞计数的情况。 还需要注意的是，青霉胺在与其他药物联合使用时应谨慎。一些药物可能会与青霉胺产生负面相互作用，导致效果降低或毒性增加。患者必须告知医生他们正在服用的所有药物，以避免潜在的并发症。 总之，青霉胺在特定医疗条件的管理中起着宝贵的作用。它在类风湿关节炎中改变疾病活动的能力以及在威尔逊病中螯合过量铜的能力突显了它在临床实践中的重要性。然而，像任何药物一样，它需要仔细考虑和监测。通过了解与青霉胺相关的益处和风险，患者和医疗保健提供者可以共同努力，以确保最佳的治疗结果。随着研究的继续，我们可能会发现这种多功能药物的更多用途，潜在地改善全球许多患者的生活。