pentobarbital

简明释义

英[/ˌpɛn.təʊˈbɑːr.bɪ.təl/]美[/ˌpɛn.təʊˈbɑːr.bɪ.təl/]

n. 戊巴比妥（同 pentobarbitone）

英英释义

单词用法

同义词

反义词

例句

1.Methods: the tail flick latency (TFL) regarded as an index, microinjection technique was used in lightly pentobarbital-anesthetized rats.

方法：以浅麻状态大鼠的甩尾反射潜伏期(TFL)为痛阈指标，采用核团内微量注射的方法。

2.Methods: the tail flick latency (TFL) regarded as an index, microinjection technique was used in lightly pentobarbital-anesthetized rats.

方法：以浅麻状态大鼠的甩尾反射潜伏期(TFL)为痛阈指标，采用核团内微量注射的方法。

3.ObjectiveTo study the effect of Cortex Albiziae solution pentobarbital-induced hypnosis in mice.

钠诱导小白鼠产生催眠作用的量效关系。

4.The veterinarian administered pentobarbital to euthanize the suffering animal.

兽医给动物注射了戊巴比妥以安乐死它。

5.In some states, pentobarbital is used as a method of lethal injection for capital punishment.

在一些州，戊巴比妥被用作死刑注射的一种方法。

6.Patients undergoing surgery may receive pentobarbital as part of their anesthesia regimen.

接受手术的患者可能会在麻醉方案中接受戊巴比妥。

7.Veterinary clinics often stock pentobarbital for emergency euthanasia procedures.

兽医诊所通常备有戊巴比妥用于紧急安乐死程序。

8.The effects of pentobarbital can be profound, leading to deep sedation.

使用戊巴比妥的效果可能非常显著，导致深度镇静。

作文

In the realm of medicine, various substances are used to treat conditions and alleviate suffering. One such substance is pentobarbital, a barbiturate that has been utilized for its sedative and anesthetic properties. Originally developed in the 1920s, pentobarbital was widely used in hospitals for its ability to induce sleep and relax patients before surgical procedures. However, its use has evolved over the decades, leading to both beneficial applications and significant ethical considerations. The mechanism of action for pentobarbital involves enhancing the effects of a neurotransmitter called gamma-aminobutyric acid (GABA). By increasing GABA activity, pentobarbital promotes sedation and reduces anxiety, making it an effective option for patients undergoing stressful medical treatments. It is important to note that while pentobarbital can provide relief, it also carries risks, including dependency and overdose, particularly when used improperly or in combination with other depressants. In recent years, pentobarbital has gained attention for its controversial role in euthanasia and assisted suicide. Some jurisdictions allow its use for individuals seeking to end their lives in a dignified manner due to terminal illness or unbearable suffering. This has sparked intense debates about the ethics of assisted dying and the responsibilities of healthcare providers. Proponents argue that allowing access to pentobarbital in these situations respects patient autonomy and alleviates suffering. Conversely, opponents raise concerns about potential coercion and the sanctity of life. In veterinary medicine, pentobarbital is commonly used to euthanize animals humanely. The drug acts quickly to induce unconsciousness, followed by respiratory arrest, ensuring a painless death. This application highlights the importance of pentobarbital in providing a compassionate end-of-life option for pets suffering from terminal conditions. Despite its medical uses, the potential for abuse of pentobarbital cannot be overlooked. As a controlled substance, it is subject to strict regulations to prevent misuse. In some cases, individuals may seek pentobarbital illicitly for recreational purposes, leading to dangerous consequences. Awareness and education about the risks associated with pentobarbital are crucial in preventing misuse and ensuring that it remains a safe and effective treatment option. In conclusion, pentobarbital serves as a powerful tool in both human and veterinary medicine, offering sedation, anesthesia, and humane euthanasia. Its historical significance and ongoing relevance underscore the complexities surrounding its use. As society grapples with the ethical implications of pentobarbital in assisted dying and the challenges of substance abuse, it is essential to approach discussions about this drug with care, compassion, and a commitment to patient welfare. Understanding the multifaceted roles of pentobarbital can help inform better practices and policies in the medical community, ultimately benefiting those in need of its therapeutic effects.

在医学领域，各种物质被用于治疗疾病和减轻痛苦。其中一种物质是戊巴比妥，这是一种巴比妥类药物，因其镇静和麻醉特性而被广泛应用。戊巴比妥最初在1920年代开发，因其能够诱导睡眠和放松患者而在医院中广泛使用，特别是在手术前。然而，随着时间的推移，其用途发生了变化，既带来了有益的应用，也引发了重大的伦理考虑。 戊巴比妥的作用机制涉及增强一种名为γ-氨基丁酸（GABA）的神经递质的作用。通过增加GABA的活性，戊巴比妥促进了镇静并减少了焦虑，使其成为接受压力较大的医疗治疗的患者的有效选择。需要注意的是，尽管戊巴比妥可以提供缓解，但它也存在风险，包括依赖性和过量，尤其是在不当使用或与其他抑制剂联合使用时。 近年来，戊巴比妥因其在安乐死和辅助自杀中的争议性角色而受到关注。一些司法管辖区允许在寻求以尊严的方式结束生命的个体中使用该药物，原因是他们面临绝症或无法忍受的痛苦。这引发了关于辅助死亡伦理的激烈辩论。支持者认为，在这些情况下允许获得戊巴比妥尊重了患者的自主权并减轻了痛苦。相反，反对者则对潜在的胁迫和生命的神圣性表示担忧。 在兽医医学中，戊巴比妥通常用于人道地安乐死动物。该药物迅速作用于诱导无意识，随后导致呼吸骤停，确保无痛死亡。这一应用突显了戊巴比妥在为遭受绝症的宠物提供富有同情心的生命终结选项中的重要性。 尽管具有医学用途，但不可忽视的是戊巴比妥的滥用潜力。作为一种受控物质，它受到严格的监管，以防止误用。在某些情况下，个体可能会非法寻求戊巴比妥以满足娱乐目的，导致危险后果。提高对与戊巴比妥相关的风险的认识和教育对于防止误用至关重要，确保其仍然是安全有效的治疗选择。 总之，戊巴比妥作为一种强大的工具，在人类和兽医医学中发挥着作用，提供镇静、麻醉和人道安乐死。其历史意义和持续相关性凸显了其使用的复杂性。随着社会在面对戊巴比妥在辅助死亡中的伦理影响以及物质滥用的挑战时进行斗争，谨慎、同情和对患者福利的承诺是进行讨论的基础。理解戊巴比妥的多方面角色可以帮助改善医疗界的实践和政策，最终使那些需要其治疗效果的人受益。