probenecid

简明释义

英[prəʊˈbenɪsɪd]美[proʊˈbenɪsɪd]

n. [药] 丙磺舒，羧苯磺丙胺

英英释义

单词用法

同义词

反义词

例句

1.The results suggest that it may be appropriate to prescribe uric acid–lowering drugs, such as allopurinol and probenecid , to these otherwise healthy individuals.

结果表明，合适的做法可能是明尿酸，降低药物，如别嘌呤醇和丙磺舒，这些健康的人。

2.The results suggest that it may be appropriate to prescribe uric acid–lowering drugs, such as allopurinol and probenecid , to these otherwise healthy individuals.

结果表明，合适的做法可能是明尿酸，降低药物，如别嘌呤醇和丙磺舒，这些健康的人。

3.The doctor prescribed probenecid to help lower the levels of uric acid in my blood.

医生开了丙磺舒来帮助降低我血液中的尿酸水平。

4.After starting treatment with probenecid, I noticed a significant decrease in my gout attacks.

开始使用丙磺舒治疗后，我注意到痛风发作明显减少。

5.Patients taking probenecid should be monitored for kidney function regularly.

服用丙磺舒的患者应定期监测肾功能。

6.The combination of probenecid and other medications can enhance their effectiveness.

将丙磺舒与其他药物联合使用可以增强其效果。

7.I learned that probenecid can also be used to increase the effectiveness of certain antibiotics.

我了解到丙磺舒还可以用于提高某些抗生素的有效性。

作文

Probenecid is a medication that plays a crucial role in the management of gout and hyperuricemia. It works by inhibiting the reabsorption of uric acid in the kidneys, which leads to increased excretion of uric acid in the urine. This mechanism is particularly beneficial for patients who suffer from high levels of uric acid, as it helps to prevent the formation of urate crystals that can lead to painful gout attacks. Understanding the significance of probenecid is essential for both healthcare professionals and patients alike. Gout is a form of arthritis characterized by sudden and severe pain, redness, and swelling in the joints, often affecting the big toe. The condition occurs when there is an excess of uric acid in the blood, leading to the formation of sharp crystals in the joints. These crystals trigger intense inflammatory responses, resulting in the classic symptoms of gout. Probenecid serves as a valuable tool in managing this condition by lowering uric acid levels in the body. The use of probenecid is not limited to gout; it has also shown promise in other medical applications. For instance, it can be used to enhance the effectiveness of certain antibiotics by prolonging their action in the body. By inhibiting renal tubular secretion, probenecid allows for higher concentrations of drugs like penicillin to remain in the bloodstream for more extended periods. This property makes it a useful adjunct therapy in treating infections, particularly those caused by susceptible bacteria. Despite its benefits, probenecid is not without side effects. Some patients may experience gastrointestinal disturbances, headache, or allergic reactions. Additionally, it is essential for healthcare providers to monitor patients closely, as probenecid can interact with other medications, potentially leading to adverse effects. Therefore, a thorough review of a patient's medication regimen is crucial before initiating treatment with probenecid. In conclusion, probenecid is a multifaceted medication that offers significant benefits in the treatment of gout and other conditions associated with elevated uric acid levels. Its ability to promote uric acid excretion and enhance drug efficacy highlights its importance in clinical practice. However, careful consideration of potential side effects and drug interactions is necessary to ensure patient safety and optimal therapeutic outcomes. As research continues to evolve, the understanding and application of probenecid will likely expand, providing new avenues for treatment and improved patient care.

丙磺舒是一种在痛风和高尿酸血症管理中发挥重要作用的药物。它通过抑制肾脏对尿酸的重吸收，从而增加尿液中尿酸的排泄。这一机制对于那些遭受高尿酸水平的患者尤其有益，因为它有助于防止尿酸盐结晶的形成，从而导致痛苦的痛风发作。理解丙磺舒的重要性对于医疗专业人员和患者来说都是至关重要的。 痛风是一种关节炎的形式，其特征是关节突然和剧烈的疼痛、红肿，通常影响大脚趾。这种情况发生在血液中尿酸过多时，导致关节内形成尖锐的结晶。这些结晶会触发强烈的炎症反应，导致痛风的典型症状。丙磺舒作为管理这种疾病的有价值工具，通过降低体内尿酸水平来发挥作用。 丙磺舒的使用并不仅限于痛风；它在其他医学应用中也显示出前景。例如，它可以用于增强某些抗生素的效果，延长它们在体内的作用。通过抑制肾小管分泌，丙磺舒使得青霉素等药物在血液中的浓度保持更长时间。这一特性使其在治疗感染（特别是由易感细菌引起的感染）中成为一种有用的辅助疗法。 尽管具有诸多好处，丙磺舒并非没有副作用。一些患者可能会经历胃肠道不适、头痛或过敏反应。此外，医疗提供者必须密切监测患者，因为丙磺舒可能与其他药物相互作用，导致不良反应。因此，在开始使用丙磺舒之前，仔细审查患者的用药方案至关重要。 总之，丙磺舒是一种多功能药物，在治疗痛风和其他与尿酸升高相关的疾病中提供显著益处。它促进尿酸排泄和增强药物功效的能力突显了它在临床实践中的重要性。然而，仔细考虑潜在的副作用和药物相互作用是确保患者安全和优化治疗结果所必需的。随着研究的不断发展，对丙磺舒的理解和应用可能会扩展，为治疗和改善患者护理提供新的途径。