radiolabeled

简明释义

英[ˌreɪdiəʊˈleɪbld]美[ˌreɪdiəˈleɪbld]

adj. 放射性标记的

v. 用放射性同位素作标记（radiolabel 的过去式）

英英释义

单词用法

同义词

反义词

例句

1.Autoradiography results confirmed the extravasation of radiolabeled SCKs in vascularized areas of the tumor, whereas no diffusion was observed in necrotic regions.

放射自显影法的结果证实，放射性标记的SCK在肿瘤血管化区域溢出，而坏死区域观察不到扩散现象。

2.Autoradiography results confirmed the extravasation of radiolabeled SCKs in vascularized areas of the tumor, whereas no diffusion was observed in necrotic regions.

放射自显影法的结果证实，放射性标记的SCK在肿瘤血管化区域溢出，而坏死区域观察不到扩散现象。

3.The most commonly used PET radiotracer is fluorodeoxyglucose (FDG), a radiolabeled form of glucose, which is consumed more avidly by tumors than by normal tissue.

最常用的PET放射示踪迹为氟脱氧葡萄糖（FDG），葡萄糖的放射示踪形式，在肿瘤组织中较正常组织消耗更快。

4.The Specialty Synthesis Group is seeking a Synthetic Radiochemist to be responsible for the carbon-14 radiolabeled chemical synthesis, purification and analysis.

现其特殊品合成部门诚寻一位放射合成化学研究人员，以从事碳-14 标志化合物的合成、纯化及分析工作。

5.The relative merits between "degradable" and "non-degradable" radiolabeled pyrimidine analogues have been compared in this paper.

本文比较可分解及不可分解放射性标帜嘧啶核苷酸之个别优点。

6.The researchers used radiolabeled compounds to trace the metabolic pathways in living organisms.

研究人员使用放射性标记化合物来追踪活体内的代谢途径。

7.In cancer studies, radiolabeled antibodies can help identify tumor locations.

在癌症研究中，放射性标记抗体可以帮助识别肿瘤位置。

8.The drug was radiolabeled to monitor its distribution in the body.

该药物被放射性标记以监测其在体内的分布。

9.Using radiolabeled isotopes allows scientists to track chemical reactions in real-time.

使用放射性标记同位素使科学家能够实时追踪化学反应。

10.The study involved the injection of radiolabeled glucose to observe brain activity.

该研究涉及注射放射性标记的葡萄糖以观察脑部活动。

作文

In the field of biomedical research, the use of radiolabeled compounds has become increasingly important. These compounds are typically tagged with a radioactive isotope, allowing scientists to track their movement and interaction within biological systems. The ability to visualize these interactions in real-time provides invaluable insights into various physiological processes and disease mechanisms. For instance, in cancer research, radiolabeled molecules can be used to study tumor metabolism and growth. By attaching a radioactive marker to a molecule that is known to be taken up by cancer cells, researchers can monitor the accumulation of the compound in tumors using imaging techniques such as positron emission tomography (PET). This not only helps in understanding how tumors behave but also assists in evaluating the effectiveness of new therapies. Moreover, radiolabeled compounds play a crucial role in pharmacokinetics, the study of how drugs are absorbed, distributed, metabolized, and excreted in the body. By using radiolabeled versions of drugs, scientists can trace their pathway through the body, determining how long they remain in circulation and where they accumulate. This information is vital for optimizing drug formulations and dosing regimens, ultimately leading to safer and more effective treatments. In addition to research applications, radiolabeled compounds are also utilized in clinical settings. For example, radiolabeled antibodies are employed in targeted radiotherapy for cancer treatment. These antibodies are designed to bind specifically to cancer cells, delivering a lethal dose of radiation directly to the tumor while minimizing damage to surrounding healthy tissue. This precision enhances the efficacy of the treatment and reduces side effects, making it a promising approach in oncology. The process of creating radiolabeled compounds involves careful consideration of several factors, including the choice of radioactive isotope, the method of labeling, and the stability of the final product. Common isotopes used for labeling include Carbon-14, Tritium, and Technetium-99m. Each isotope has its own unique properties, such as half-life and energy emissions, which must align with the specific goals of the study or treatment. Despite the many advantages of using radiolabeled compounds, there are also challenges associated with their use. Safety concerns regarding radiation exposure must be addressed, particularly when working with human subjects. Regulatory guidelines and ethical considerations play a significant role in the development and application of radiolabeled substances in research and medicine. In conclusion, the incorporation of radiolabeled compounds into biomedical research and clinical practice has revolutionized our understanding of complex biological systems and advanced therapeutic strategies. As technology continues to evolve, the potential applications of radiolabeled compounds will likely expand, offering new opportunities for scientific discovery and improved patient care. The ongoing exploration of this field promises to yield further breakthroughs that could significantly impact health outcomes worldwide.

在生物医学研究领域，使用放射性标记化合物变得越来越重要。这些化合物通常用放射性同位素标记，允许科学家跟踪它们在生物系统中的运动和相互作用。实时可视化这些相互作用提供了对各种生理过程和疾病机制的宝贵见解。 例如，在癌症研究中，放射性标记分子可用于研究肿瘤代谢和生长。通过将放射性标记附加到已知被癌细胞吸收的分子上，研究人员可以使用正电子发射断层扫描（PET）等成像技术监测该化合物在肿瘤中的积累。这不仅有助于理解肿瘤的行为，还帮助评估新疗法的有效性。 此外，放射性标记化合物在药代动力学中发挥着至关重要的作用，即研究药物在体内的吸收、分布、代谢和排泄。通过使用放射性标记版本的药物，科学家可以追踪其在体内的路径，确定它们在循环中停留多长时间以及在哪里积累。这些信息对于优化药物配方和给药方案至关重要，最终有助于更安全、更有效的治疗。 除了研究应用，放射性标记化合物还在临床环境中被广泛利用。例如，放射性标记抗体被用于癌症治疗中的靶向放射治疗。这些抗体旨在特异性结合癌细胞，将致命剂量的辐射直接输送到肿瘤，同时最小化对周围健康组织的损害。这种精准性增强了治疗的有效性并减少了副作用，使其成为肿瘤学中一种有前景的方法。 制作放射性标记化合物的过程涉及多个因素的仔细考虑，包括放射性同位素的选择、标记方法和最终产品的稳定性。常用的标记同位素包括碳-14、氚和锝-99m。每种同位素都有其独特的特性，如半衰期和能量释放，必须与研究或治疗的具体目标相一致。 尽管使用放射性标记化合物有许多优点，但它们的使用也面临挑战。必须解决关于辐射暴露的安全问题，特别是在与人类受试者合作时。监管指南和伦理考虑在研究和医学中放射性标记物质的开发和应用中发挥着重要作用。 总之，将放射性标记化合物纳入生物医学研究和临床实践，彻底改变了我们对复杂生物系统的理解，并推动了治疗策略的进步。随着技术的不断发展，放射性标记化合物的潜在应用可能会扩大，为科学发现和改善患者护理提供新的机会。对这一领域的持续探索承诺将带来进一步的突破，这可能会显著影响全球的健康结果。