reuptake

简明释义

英[riːˈʌpteɪk]美[riˈʌpˌtek]

n. 再摄取；再吸收

英英释义

单词用法

同义词

反义词

例句

1.Drugs like Celexa, Zoloft and Paxil -- known as, or selective seratonin reuptake inhibitors -- are often used to treat depression, anxiety and other mental illnesses.

它们常常用于治疗抑郁、焦虑和其他精神疾病。

2.People complained of more side-effects from serotonin-norepinephrine reuptake inhibitors or SNRIs, a newer, often more expensive class of antidepressants, the survey found.

人们抱怨昂贵的新药——选择性5-羟色胺/去甲肾上腺素重吸收抑制剂(SNRI)——副作用更多。

3.Thyroid hormones decrease systemic vascular resistance by increasing production of nitric oxide and by increasing calcium reuptake within the arterioles, which leads to smooth muscle relaxation55.

甲状腺激素通过增加一氧化氮的产生和通过增加小动脉内的钙再摄取而降低全身血管阻力，这导致平滑肌松弛。

4.The Cleveland Clinic recommends antidepressants known as selective serotonin reuptake inhibitors (SSRIs, such as Prozac and Zoloft) because they don't raise blood pressure.

克利夫兰诊所称赞抗抑郁药物(简称SSRIS，如百忧解和左洛复)之所以被称为选择性的再摄取血清素抑制剂是因为它们不会使血压提高。

5.Most antidepression pills prescribed today are selective serotonin reuptake inhibitors (SSRIs), a type of drug that boosts the amount of serotonin hanging around in the brain.

今天大多数的抗抑郁剂处方都是选择性复合胺再吸收抑制剂(SSRIs)，一种可以增加大脑周围血液中的复合胺含量的药品。

6.To study effect of aromatic hydrocarbon solvents on the reuptake of amino acid by primary cultured glia cells.

研究芳烃类有机溶剂对原代培养大鼠神经胶质细胞的谷氨酸重摄取的影响。

7.Standard, first-line OCD treatment typically includes selective serotonin-reuptake inhibitors (SSRIs) and tricyclic antidepressants such as clomipramine, along with behavioral therapies.

标准治疗就是使用一线OCD治疗药物包括选择性5-羟色胺再吸收抑制剂和三环抗抑郁药如氯丙咪嗪再加上行为治疗。

8.The problems relate to a class of drug known as SSRIs (selective serotonin reuptake inhibitors), which includes Prozac and, in particular, the British-made Seroxat.

上述问题涉及到一种被称为选择性血清素再吸收抑制剂(SSRIs)的药物，其中含有百忧解，尤其是英国生产的帕罗西汀。

9.The newest and most popular types of antidepressant medications are called selective serotonin reuptake inhibitors (SSRIs).

最新的也是最流行的抗抑郁药物类型，我们称为选择性血清素再吸收抑制剂(SSRIs)。

10.The process of neurotransmitter reuptake is crucial for regulating mood.

神经递质的再摄取过程对调节情绪至关重要。

11.Selective serotonin reuptake inhibitors are often prescribed for depression.

选择性血清素再摄取抑制剂通常用于治疗抑郁症。

12.Understanding reuptake mechanisms can help in developing new medications.

理解再摄取机制可以帮助开发新药物。

13.Caffeine can influence the reuptake of certain neurotransmitters.

咖啡因可以影响某些神经递质的再摄取。

14.Inhibiting the reuptake of dopamine can lead to increased feelings of pleasure.

抑制多巴胺的再摄取会导致愉悦感增强。

作文

In the realm of neuroscience, the term reuptake refers to the process by which neurotransmitters are reabsorbed by the presynaptic neuron after they have transmitted signals across a synapse. This mechanism is crucial for maintaining the balance of neurotransmitters in the brain and ensuring proper communication between neurons. When a neuron fires, it releases neurotransmitters into the synaptic cleft, where they bind to receptors on the postsynaptic neuron, leading to the propagation of a neural signal. However, once their job is done, these neurotransmitters need to be cleared from the synapse to prevent continuous stimulation of the postsynaptic neuron. This is where reuptake comes into play. The reuptake process involves specialized proteins known as transporters that are embedded in the presynaptic neuron's membrane. These transporters recognize and bind to the neurotransmitters in the synaptic cleft and facilitate their return to the presynaptic neuron. For example, serotonin, a neurotransmitter associated with mood regulation, undergoes reuptake through the serotonin transporter (SERT). Once reabsorbed, serotonin can be repackaged into vesicles for future use or broken down by enzymes. The significance of reuptake extends beyond mere neurotransmitter recycling; it plays a pivotal role in pharmacology and the treatment of various mental health disorders. Many antidepressant medications, such as selective serotonin reuptake inhibitors (SSRIs), work by blocking the reuptake of serotonin. By inhibiting this process, SSRIs increase the availability of serotonin in the synaptic cleft, enhancing its effects and helping to alleviate symptoms of depression. This therapeutic strategy highlights the importance of understanding reuptake in developing effective treatments for mental health conditions. Moreover, dysregulation of reuptake mechanisms can contribute to various neurological disorders. For instance, in conditions like anxiety and depression, there may be an imbalance in neurotransmitter levels due to altered reuptake processes. Understanding these mechanisms allows researchers to explore novel therapeutic targets and develop interventions that can restore normal neurotransmitter function. In conclusion, reuptake is a fundamental process in the field of neuroscience that ensures the efficient recycling of neurotransmitters, thereby facilitating effective communication between neurons. Its implications extend to the development of psychiatric medications and our understanding of various mental health disorders. As research continues to evolve, further insights into the intricacies of reuptake may lead to innovative treatments and improved outcomes for individuals struggling with neurological and psychological challenges.

在神经科学领域，术语再摄取指的是神经递质在通过突触传递信号后被突触前神经元重新吸收的过程。这个机制对维持大脑中神经递质的平衡以及确保神经元之间的正常通信至关重要。当一个神经元发射时，它会将神经递质释放到突触间隙中，在那里它们与突触后神经元上的受体结合，导致神经信号的传播。然而，一旦它们的工作完成，这些神经递质需要从突触中清除，以防止对突触后神经元的持续刺激。这就是再摄取发挥作用的地方。 再摄取过程涉及嵌入在突触前神经元膜中的特殊蛋白质，称为转运体。这些转运体识别并结合突触间隙中的神经递质，并促进其返回突触前神经元。例如，与情绪调节相关的神经递质血清素，通过血清素转运体（SERT）进行再摄取。一旦被重新吸收，血清素可以被重新包装到囊泡中以备将来使用，或被酶分解。 再摄取的重要性不仅仅局限于神经递质的回收；它在药理学和各种心理健康障碍的治疗中扮演着关键角色。许多抗抑郁药物，如选择性血清素再摄取抑制剂（SSRIs），通过阻断血清素的再摄取来发挥作用。通过抑制这一过程，SSRIs增加了突触间隙中血清素的可用性，从而增强其效果，帮助缓解抑郁症状。这种治疗策略突显了理解再摄取在开发有效心理健康治疗中的重要性。 此外，再摄取机制的失调可能导致各种神经系统疾病。例如，在焦虑和抑郁等病症中，由于再摄取过程的改变，神经递质水平可能失衡。理解这些机制使研究人员能够探索新的治疗靶点，并开发能够恢复正常神经递质功能的干预措施。 总之，再摄取是神经科学领域的一个基本过程，它确保了神经递质的有效回收，从而促进神经元之间的有效通信。其影响扩展到精神药物的发展以及我们对各种心理健康障碍的理解。随着研究的不断发展，对再摄取复杂性的进一步深入了解可能会导致创新治疗方法的出现，并改善面临神经和心理挑战的个体的结果。