rifampin

简明释义

英[raɪˈfæmpɪn]美[rɪˈfæmpɪn]

n. （美）利福平（抗生素类药，等于 rifampicin）

英英释义

单词用法

同义词

反义词

例句

1.For thosewith negative smears, dapsone and rifampin for one year is the standard of carein the United States.

如果是阴性，服用氨苯砜与利福平1年是标准疗法。

2.ObjectiveEstablishement one kind of accurate method which determines the rifampin content in eye drops.

目的建立一种准确的检测滴眼用利福平含量的方法。

3.Rifampin was the least costly treatment regimen for any child arriving from an area with an isoniazid-resistance rate exceeding 11%.

利福平对于来自异烟肼耐药率超过11%地区的儿童是成本最低的治疗。

4.Drug susceptibility test showed that 7 of them were drug-sensitive and the remaining 1 was resistant to rifampin and isoniazid.

药敏试验结果1例对异烟肼、利福平耐药，其余7例为敏感菌株。

5.Conclusion DNA chip technology has high sensitivity and specificity in detection of rifampin-resistant M. tuberculosis and may be applied in clinical diagnosis.

结论用DNA芯片检测结核菌对利福平的耐药性具有较高的特异性和敏感性，可用于临床结核菌耐药性检测。

6.Objective To probe the molecular mechanisms of rifampin resistance of the cell wall deficient Mycobacterium tuberculosis.

目的探讨细胞壁缺陷结核分枝杆菌形成利福平耐药性的分子机制。

7.Because the probe of 517 rifampin-resistant did not be dotted on the gene chip, only sites of 518 and 526 mutations were detected, which were consistent with the results of DNA sequencing.

另有两株为517和518、526和517位双位点突变，因为芯片上未点517位突变的探针，所以只检测到518和526位的突变，该突变与测序结果完全一致。

8.The doctor prescribed rifampin for the treatment of tuberculosis.

医生开了利福平来治疗结核病。

9.Patients taking rifampin should be monitored for liver function.

服用利福平的患者应监测肝功能。

10.It is important to complete the full course of rifampin to prevent drug resistance.

完成整个利福平疗程以防止药物耐药性是很重要的。

11.Some medications may interact with rifampin, so consult your doctor.

某些药物可能与利福平相互作用，因此请咨询医生。

12.Side effects of rifampin can include nausea and fatigue.

服用利福平的副作用可能包括恶心和疲劳。

作文

Rifampin is an essential antibiotic that plays a critical role in the treatment of various bacterial infections, particularly tuberculosis. This medication is part of the rifamycin group and is known for its ability to inhibit bacterial RNA synthesis. The mechanism of action of rifampin (利福平) involves binding to the beta-subunit of bacterial RNA polymerase, which prevents the transcription of DNA into RNA. This effectively halts the growth of bacteria, making rifampin (利福平) a powerful tool in combating infections. One of the most significant uses of rifampin (利福平) is in the treatment of tuberculosis (TB), a disease caused by the bacterium Mycobacterium tuberculosis. TB remains a global health challenge, and the emergence of drug-resistant strains has made effective treatment options even more crucial. Rifampin (利福平) is often used in combination with other antibiotics to ensure a comprehensive approach to treatment. This combination therapy helps to prevent the development of resistance and increases the likelihood of successful outcomes. In addition to tuberculosis, rifampin (利福平) is also effective against other infections such as leprosy and certain types of staphylococcal infections. Its broad-spectrum activity makes it a versatile antibiotic, although it is primarily associated with TB treatment. Patients prescribed rifampin (利福平) must be monitored closely due to potential side effects, which can include liver toxicity, gastrointestinal disturbances, and changes in urine color. Moreover, rifampin (利福平) is known to interact with various medications, which can affect their efficacy. For example, it can reduce the effectiveness of oral contraceptives, leading to unintended pregnancies. Therefore, healthcare providers must educate patients about these interactions and consider alternative contraceptive methods during treatment. The development of rifampin (利福平) marked a significant advancement in the fight against infectious diseases. Before its introduction, tuberculosis was often a death sentence, and the options for treatment were limited. With the availability of rifampin (利福平), healthcare professionals gained a potent weapon against this devastating disease. However, the rise of multidrug-resistant tuberculosis has highlighted the need for continued research and development of new antibiotics. In conclusion, rifampin (利福平) is a vital antibiotic that has transformed the landscape of infectious disease treatment, particularly in the context of tuberculosis. Its ability to inhibit bacterial growth through RNA synthesis interference has saved countless lives. Nevertheless, the careful management of its use is essential to mitigate side effects and prevent resistance. As we move forward, ongoing research into rifampin (利福平) and similar antibiotics will be crucial in ensuring effective treatment options remain available for future generations.

利福平是一种重要的抗生素，在治疗各种细菌感染，特别是结核病方面发挥着关键作用。这种药物属于利福霉素类，以其抑制细菌RNA合成的能力而闻名。rifampin（利福平）的作用机制涉及与细菌RNA聚合酶的β亚基结合，从而阻止DNA转录为RNA。这有效地停止了细菌的生长，使得rifampin（利福平）成为对抗感染的强大工具。 rifampin（利福平）最重要的用途之一是在治疗由结核分枝杆菌引起的结核病（TB）中。结核病仍然是全球健康挑战，而耐药菌株的出现使得有效的治疗选择变得更加重要。rifampin（利福平）通常与其他抗生素联合使用，以确保全面的治疗方法。这种联合疗法有助于防止耐药性的产生，并增加成功结果的可能性。 除了结核病，rifampin（利福平）还对麻风和某些类型的金黄色葡萄球菌感染有效。其广谱活性使其成为一种多功能抗生素，尽管它主要与结核病治疗相关。被开处方使用rifampin（利福平）的患者必须密切监测，因为可能出现的副作用包括肝毒性、胃肠道不适和尿液颜色变化。 此外，rifampin（利福平）还与多种药物相互作用，这可能会影响它们的疗效。例如，它可以降低口服避孕药的效果，导致意外怀孕。因此，医疗提供者必须教育患者有关这些相互作用，并在治疗期间考虑替代避孕方法。 rifampin（利福平）的开发标志着对抗传染病的重要进展。在其引入之前，结核病往往是死刑，治疗选择有限。随着rifampin（利福平）的可用性，医疗专业人员获得了一种强大的武器来对抗这种毁灭性的疾病。然而，多药耐药性结核病的上升突显了继续研究和开发新抗生素的必要性。 总之，rifampin（利福平）是一种重要的抗生素，改变了传染病治疗的格局，特别是在结核病的背景下。它通过干扰RNA合成抑制细菌生长的能力挽救了无数生命。然而，仔细管理其使用对于减轻副作用和防止耐药性至关重要。随着我们向前发展，对rifampin（利福平）及类似抗生素的持续研究将对确保未来几代人仍能获得有效治疗选择至关重要。