scleroderma

简明释义

英[ˌsklɪərəˈdɜːmə]美[ˌskleərəˈdɜːrmər]

n. [内科] 硬皮病

英英释义

单词用法

同义词

反义词

例句

1.Autoimmune: such as lupus erythematosus, rheumatoid arthritis, scleroderma, and other.

自身免疫性：如红斑狼疮、类风湿关节炎、硬皮病等。

2.However, there is increasingly strong evidence of a genetic predisposition to scleroderma.

然而，存在硬皮病遗传因素的日益增长的证据。

3.It is feasible to utilize Beauveria bassiana carried by Scleroderma sichuanensis Xiao to infect Monochamus alternatus larva voluntarily.

利用川硬皮肿腿蜂携带球孢白僵菌主动感染松墨天牛幼虫的设想是可行的。

4.The goal is that better management of scleroderma as a multi-spectrum, chronic disease will be achieved.

我们的目标是更好地管理作为一个多光谱，硬皮病，慢性疾病将得以实现。

5.Objective To study the effect of VEGF on the hair growth in mice with scleroderma.

目的观察VEGF对硬皮病小鼠模型毛发生长的作用。

6.Scleroderma is a chronic disease that lasts many months to years.

硬皮病是一种可以持续数月至数年的疾病。

7.The case was diagnosed as lichen sclerosus et atrophicus with localized scleroderma .

患者诊断为硬化萎缩性苔藓合并局限性硬皮病。

8.The microvascular modification is pathologic base of most clinical manifestation and complication of scleroderma.

微血管病变是硬皮病大部分临床表现及并发症的病理基础。

9.These are often used to treat conditions such as scleroderma that can cause extensive scarring and hardening of the skin.

这些都是常用的治疗条件，如硬皮病可导致广泛的疤痕和硬化的皮肤。

10.The doctor diagnosed her with scleroderma, a condition that causes hardening of the skin.

医生诊断她患有硬皮病，这是一种导致皮肤硬化的疾病。

11.Patients with scleroderma often experience joint pain and stiffness.

患有硬皮病的患者常常会感到关节疼痛和僵硬。

12.Research is ongoing to find new treatments for scleroderma.

研究仍在进行中，以寻找新的硬皮病治疗方法。

13.She joined a support group for people living with scleroderma.

她加入了一个为生活在硬皮病中的人们提供支持的团体。

14.Symptoms of scleroderma can vary from person to person.

每个人的硬皮病症状可能有所不同。

作文

Scleroderma is a complex autoimmune disease that affects the skin and internal organs, leading to a hardening and tightening of the connective tissues. The term 'scleroderma' comes from the Greek words 'sclero,' meaning hard, and 'derma,' meaning skin. This condition can manifest in various forms, with symptoms ranging from mild to severe. In this essay, we will explore the nature of scleroderma (硬皮病), its symptoms, causes, diagnosis, and treatment options available for those affected by this challenging disease. The symptoms of scleroderma (硬皮病) can vary significantly from person to person. One of the most recognizable signs is the thickening and hardening of the skin, which often begins in the fingers and can spread to other parts of the body. This skin change can lead to discomfort, restricted movement, and cosmetic concerns. Additionally, individuals may experience Raynaud's phenomenon, where the fingers and toes turn white or blue in response to cold temperatures or stress. Other symptoms may include joint pain, fatigue, and difficulty swallowing due to esophageal involvement. There are two main types of scleroderma (硬皮病): localized and systemic. Localized scleroderma primarily affects the skin and is generally less severe. It may present as patches of thickened skin, often referred to as morphea, or as linear scleroderma, which appears as bands of hardened skin. On the other hand, systemic scleroderma can impact not only the skin but also internal organs such as the heart, lungs, kidneys, and digestive tract, making it a more serious condition that requires careful management. The exact cause of scleroderma (硬皮病) remains unclear, but it is believed to involve a combination of genetic predisposition and environmental factors. Some researchers suggest that certain infections or exposure to toxins may trigger the immune system to attack the body's own tissues, resulting in the excessive production of collagen, a protein that gives skin its structure. This overproduction leads to the characteristic hardening associated with the disease. Diagnosing scleroderma (硬皮病) can be challenging, as its symptoms can mimic those of other conditions. A thorough medical history, physical examination, and specific tests, such as blood tests for autoantibodies and imaging studies, are essential for an accurate diagnosis. Early detection is crucial, especially in the case of systemic scleroderma, as it allows for prompt intervention and better management of symptoms. Treatment for scleroderma (硬皮病) is tailored to the individual's symptoms and the severity of the disease. While there is currently no cure for scleroderma, various medications can help manage symptoms and slow the progression of the disease. For instance, immunosuppressants may be prescribed to reduce immune system activity, while medications for Raynaud's phenomenon can improve blood flow to the extremities. Physical therapy and occupational therapy can also play a vital role in maintaining mobility and enhancing the quality of life for those affected. In conclusion, scleroderma (硬皮病) is a multifaceted autoimmune disease that presents unique challenges for those diagnosed with it. Understanding its symptoms, causes, and treatment options is essential for patients and their families. Ongoing research is critical to uncovering the underlying mechanisms of this disease and developing more effective therapies. By raising awareness about scleroderma (硬皮病), we can foster a supportive community for those affected and promote better healthcare outcomes.

硬皮病是一种复杂的自身免疫性疾病，影响皮肤和内脏，导致结缔组织的硬化和紧缩。‘硬皮病’一词源自希腊语，‘sclero’意为硬，‘derma’意为皮肤。这种疾病可以以多种形式表现，症状从轻微到严重不等。在这篇文章中，我们将探讨scleroderma（硬皮病）的性质、症状、原因、诊断以及可供受影响者使用的治疗选择。 scleroderma（硬皮病）的症状因人而异。其中最明显的迹象之一是皮肤的增厚和硬化，这通常从手指开始，可能扩散到身体其他部位。这种皮肤变化会导致不适、运动受限和美容问题。此外，患者还可能经历雷诺现象，即在寒冷或压力下，手指和脚趾变白或变蓝。其他症状可能包括关节疼痛、疲劳和由于食道受累而导致的吞咽困难。 scleroderma（硬皮病）主要有两种类型：局部型和系统型。局部型硬皮病主要影响皮肤，通常较轻微。它可能表现为皮肤增厚的斑块，通常称为局限性硬皮病，或呈现为线性硬皮病，表现为硬化皮肤的带状。另一方面，系统型硬皮病不仅可以影响皮肤，还可以影响心脏、肺、肾脏和消化道等内脏器官，使其成为一种更严重的疾病，需要仔细管理。 scleroderma（硬皮病）的确切原因仍不清楚，但据信涉及遗传易感性和环境因素的结合。一些研究人员认为，某些感染或接触毒素可能触发免疫系统攻击自身组织，导致胶原蛋白的过度生成，胶原蛋白是一种赋予皮肤结构的蛋白质。这种过度生成导致了与该疾病相关的特征性硬化。 诊断scleroderma（硬皮病）可能具有挑战性，因为其症状可能与其他疾病相似。全面的病史、体检和特定测试（例如针对自身抗体的血液测试和影像学检查）对于准确诊断至关重要。早期发现至关重要，特别是在系统型硬皮病的情况下，因为这可以及时干预并更好地管理症状。 针对scleroderma（硬皮病）的治疗根据个体症状和疾病的严重程度量身定制。虽然目前没有治愈硬皮病的方法，但各种药物可以帮助管理症状并减缓疾病的进展。例如，可以开具免疫抑制剂以减少免疫系统的活性，而用于雷诺现象的药物可以改善四肢的血流。物理治疗和职业治疗也在维持活动能力和提高受影响者生活质量方面发挥着重要作用。 总之，scleroderma（硬皮病）是一种多面向的自身免疫性疾病，为被诊断者带来了独特的挑战。了解其症状、原因和治疗选择对患者及其家庭至关重要。持续的研究对于揭示该疾病的潜在机制和开发更有效的治疗方法至关重要。通过提高对scleroderma（硬皮病）的认识，我们可以为受影响者营造一个支持性的社区，并促进更好的医疗结果。