selegiline

简明释义

英[ˌsɛlɪˈdʒiːlaɪn]美[ˌsɛlɪˈdʒilˌin]

丙炔苯丙胺

司来吉兰

司立吉林（食欲抑制药）

英英释义

单词用法

同义词

反义词

例句

1.From 1-phenyl-2-propylamine, selegiline hydrochloride, an anti-Parksins drug, was synthesized via N-methylation, enantiomer separation, N-alkylation and salt formation with an overall yield of 42.2%.

以1- 苯基- 2-丙胺为原料，经N- 甲基化、拆分、N-炔基化、成盐共4步反应合成盐酸司来吉兰，总收率为42。

2.From 1-phenyl-2-propylamine, selegiline hydrochloride, an anti-Parksins drug, was synthesized via N-methylation, enantiomer separation, N-alkylation and salt formation with an overall yield of 42.2%.

以1- 苯基- 2-丙胺为原料，经N- 甲基化、拆分、N-炔基化、成盐共4步反应合成盐酸司来吉兰，总收率为42。

3.Selegiline is a smelly yellow ointment made from cows' brains, used to treat conditions from Parkinson's disease to depression, and is said to sharpen up the mind.

司立吉林是一种用牛脑制成的味臭色黄的软膏，用于治疗帕金森症、抑郁症等疾病。据说，它有提神醒脑的功效。

4.The doctor prescribed selegiline for the treatment of early-stage Parkinson's disease.

医生开了西乐葆用于治疗早期帕金森病。

5.Patients taking selegiline should be monitored for potential side effects.

服用西乐葆的患者应该监测潜在的副作用。

6.Research shows that selegiline may help improve mood in patients with depression.

研究表明，西乐葆可能有助于改善抑郁症患者的情绪。

7.When combined with certain medications, selegiline can lead to dangerous interactions.

与某些药物结合时，西乐葆可能会导致危险的相互作用。

8.Long-term use of selegiline has been linked to a reduced risk of dementia.

长期使用西乐葆与降低痴呆风险有关。

作文

Selegiline, a selective monoamine oxidase inhibitor (MAOI), is primarily used in the treatment of Parkinson's disease and major depressive disorder. This medication works by increasing the levels of certain neurotransmitters in the brain, specifically dopamine, which is crucial for regulating mood and movement. The significance of selegiline (司来吉兰) in the field of neurology cannot be overstated, as it provides patients with an improved quality of life by alleviating symptoms associated with these conditions. Parkinson's disease is a progressive neurological disorder that affects movement. Patients often experience tremors, stiffness, and difficulty with balance and coordination. By inhibiting the enzyme monoamine oxidase, selegiline (司来吉兰) helps to preserve dopamine levels in the brain, thereby reducing these motor symptoms. Research has shown that early intervention with selegiline (司来吉兰) can slow the progression of the disease and improve overall patient outcomes. In addition to its use in Parkinson's disease, selegiline (司来吉兰) has also been studied for its effectiveness in treating depression. Some studies suggest that it may be particularly beneficial for patients who have not responded well to traditional antidepressants. This is likely due to its unique mechanism of action, which not only increases dopamine levels but also enhances the availability of other neurotransmitters such as norepinephrine and serotonin. The administration of selegiline (司来吉兰) can vary depending on the condition being treated. It is available in various forms, including oral tablets and transdermal patches. The latter allows for a steady release of the medication into the bloodstream, providing consistent therapeutic effects. However, it is important for patients to follow their healthcare provider's instructions carefully, as improper use can lead to adverse effects or interactions with other medications. Despite its benefits, selegiline (司来吉兰) is not without risks. Patients taking this medication must be aware of potential side effects, which can include dizziness, insomnia, and gastrointestinal issues. Furthermore, because selegiline (司来吉兰) is an MAOI, it can interact with certain foods and medications, leading to serious complications. For instance, consuming tyramine-rich foods, such as aged cheeses and cured meats, can cause hypertensive crises in individuals taking selegiline (司来吉兰). Therefore, dietary restrictions are often necessary to ensure safety while on this medication. In conclusion, selegiline (司来吉兰) plays a vital role in the management of Parkinson's disease and depression. Its ability to enhance neurotransmitter levels makes it a valuable option for patients who need additional support in managing their symptoms. As with any medication, it is essential for patients to work closely with their healthcare providers to monitor their progress and adjust their treatment plan as needed. With ongoing research and advancements in the understanding of this medication, there is hope for even greater efficacy and safety in the future, further solidifying the importance of selegiline (司来吉兰) in modern medicine.

司来吉兰（Selegiline）是一种选择性单胺氧化酶抑制剂（MAOI），主要用于治疗帕金森病和重度抑郁症。这种药物通过增加大脑中某些神经递质的水平，特别是多巴胺，从而发挥作用，多巴胺对于调节情绪和运动至关重要。司来吉兰（selegiline）在神经学领域的重要性不容小觑，因为它通过缓解与这些疾病相关的症状，为患者提供了改善生活质量的机会。 帕金森病是一种进行性的神经系统疾病，影响运动。患者通常会经历震颤、僵硬以及平衡和协调困难。通过抑制单胺氧化酶这种酶，司来吉兰（selegiline）有助于维持大脑中的多巴胺水平，从而减少这些运动症状。研究表明，早期干预使用司来吉兰（selegiline）可以减缓疾病进程并改善整体患者结果。 除了用于帕金森病之外，司来吉兰（selegiline）还被研究用于治疗抑郁症。一些研究表明，对于那些对传统抗抑郁药反应不佳的患者，它可能特别有效。这可能与其独特的作用机制有关，不仅增加多巴胺水平，还增强去甲肾上腺素和血清素等其他神经递质的可用性。 根据治疗的具体情况，司来吉兰（selegiline）的给药方式可能有所不同。它以多种形式提供，包括口服片剂和透皮贴片。后者允许药物在血液中持续释放，提供一致的治疗效果。然而，患者必须仔细遵循医疗提供者的指示，因为不当使用可能导致不良反应或与其他药物的相互作用。 尽管有其益处，司来吉兰（selegiline）也并非没有风险。服用这种药物的患者必须了解潜在的副作用，可能包括头晕、失眠和胃肠问题。此外，由于司来吉兰（selegiline）是一种MAOI，它可能与某些食物和药物相互作用，导致严重并发症。例如，摄入富含酪胺的食物，如陈年奶酪和腌制肉类，可能会导致服用司来吉兰（selegiline）的个体发生高血压危机。因此，在使用此药物时，通常需要饮食限制以确保安全。 总之，司来吉兰（selegiline）在帕金森病和抑郁症管理中发挥着至关重要的作用。它增强神经递质水平的能力使其成为需要额外支持以管理症状的患者的宝贵选择。与任何药物一样，患者与医疗提供者密切合作，监测其进展并根据需要调整治疗计划至关重要。随着对这种药物理解的不断深入和研究的推进，未来对其疗效和安全性的期望更高，进一步巩固了司来吉兰（selegiline）在现代医学中的重要性。